{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,15]],"date-time":"2026-09-15T02:51:16Z","timestamp":1789440676885,"version":"build-2803163510"},"reference-count":57,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2011,12]]},"abstract":"\n Object<\/jats:title>\n Chiropractic manipulation of the cervical spine is a known cause of craniocervical arterial dissections. In this paper, the authors describe the patterns of arterial injury after chiropractic manipulation and their management in the modern endovascular era.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n A prospectively maintained endovascular database was reviewed to identify patients presenting with craniocervical arterial dissections after chiropractic manipulation. Factors assessed included time to symptomatic presentation, location of the injured arterial segment, neurological symptoms, endovascular treatment, surgical treatment, clinical outcome, and radiographic follow-up.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n \n Thirteen patients (8 women and 5 men, mean age 44 years, range 30\u201373 years) presented with neurological deficits, head and neck pain, or both, typically within hours or days of chiropractic manipulation. Arterial dissections were identified along the entire course of the vertebral artery, including the origin through the V\n 4<\/jats:sub>\n segment. Three patients had vertebral artery dissections that continued rostrally to involve the basilar artery. Two patients had dissections of the internal carotid artery (ICA): 1 involved the cervical ICA and 1 involved the petrocavernous ICA. Stenting was performed in 5 cases, and thrombolysis of the basilar artery was performed in 1 case. Three patients underwent emergency cerebellar decompression because of impending herniation. Six patients were treated with medication alone, including either anticoagulation or antiplatelet therapy. Clinical follow-up was obtained in all patients (mean 19 months). Three patients had permanent neurological deficits, and 1 died of a massive cerebellar stroke. The remaining 9 patients recovered completely. Of the 12 patients who survived, radiographic follow-up was obtained in all but 1 of the most recently treated patients (mean 12 months). All stents were widely patent at follow-up.\n <\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Chiropractic manipulation of the cervical spine can produce dissections involving the cervical and cranial segments of the vertebral and carotid arteries. These injuries can be severe, requiring endovascular stenting and cranial surgery. In this patient series, a significant percentage (31%, 4\/13) of patients were left permanently disabled or died as a result of their arterial injuries.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2011.8.jns111212","type":"journal-article","created":{"date-parts":[[2011,9,16]],"date-time":"2011-09-16T10:41:58Z","timestamp":1316169718000},"page":"1197-1205","source":"Crossref","is-referenced-by-count":68,"title":["Craniocervical arterial dissections as sequelae of chiropractic manipulation: patterns of injury and management"],"prefix":"10.3171","volume":"115","author":[{"given":"Felipe C.","family":"Albuquerque","sequence":"first","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yin C.","family":"Hu","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shervin R.","family":"Dashti","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Adib A.","family":"Abla","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Justin C.","family":"Clark","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Brian","family":"Alkire","sequence":"additional","affiliation":[{"name":"Department of Electroneurodiagnostics, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center, Phoenix, Arizona"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Theodore","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Cameron G.","family":"McDougall","sequence":"additional","affiliation":[{"name":"Division of Neurological Surgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns111212","series-title":"J Fam Pract","first-page":"475","article-title":"Complications of spinal manipulation: a comprehensive review of the literature","volume":"42","author":"Assendelft","year":"1996"},{"key":"b2-jns111212","series-title":"Informed Consent Guidelines","author":"Association of Chiropractic Colleges"},{"key":"b3-jns111212","series-title":"South Med J","first-page":"1507","article-title":"Brain stem infarction due to chiropractic manipulation of the cervical spine","volume":"76","author":"Braun","year":"1983"},{"key":"b4-jns111212","series-title":"Radiology","first-page":"80","article-title":"Tatlow WF: Radiographic studies of the vertebral arteries in cadavers. 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