{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,21]],"date-time":"2026-09-21T16:28:33Z","timestamp":1790008113532,"version":"4.0.1"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2013,2]]},"abstract":"\n Object<\/jats:title>\n The aim of this study was to explore the feasibility of intraoperative visuospatial mapping with the same criteria currently used to define essential language areas.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The authors compared surgical procedures in 2 patients with similar tumors (Grade II oligodendroglioma in the right parietal lobe) undergoing awake, image-assisted surgery for lesion removal with intraoperative neurophysiological monitoring. The line bisection task was used in both patients but with different criteria.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n In the first case, the authors respected any area, even within the tumor, where significant interference was found (a stimulation-induced error in 2 of 3 applications defined an essential area). In the second case, they removed 1 essential area located in the tumor and recorded an uneventful clinical response soon thereafter. They continued to monitor the patient without stimulation and stopped the resection when the patient was close to the criteria valid for defining spatial neglect. The signs of spatial neglect were present for 3 days postoperatively and then cleared spontaneously. Subtotal tumor removal was achieved in both cases.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Evidence in the present study reveals that areas for visuospatial functions cannot be assessed with the same criteria used for language functions, since essential areas located in the tumor can be safely removed.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2012.12.focus12358","type":"journal-article","created":{"date-parts":[[2013,2,1]],"date-time":"2013-02-01T13:36:20Z","timestamp":1359725780000},"page":"E4","source":"Crossref","is-referenced-by-count":18,"title":["Intraoperative cortical mapping of visuospatial functions in parietal low-grade tumors: changing perspectives of neurophysiological mapping"],"prefix":"10.3171","volume":"34","author":[{"given":"Andrea","family":"Talacchi","sequence":"first","affiliation":[{"name":"Sections of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Giovanna Maddalena","family":"Squintani","sequence":"additional","affiliation":[{"name":"Unit of Neurology, Department of Neurosciences, University Hospital, Verona, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Emanuele","sequence":"additional","affiliation":[{"name":"Physiology and Psychology, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Tramontano","sequence":"additional","affiliation":[{"name":"Sections of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Barbara","family":"Santini","sequence":"additional","affiliation":[{"name":"Sections of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Silvia","family":"Savazzi","sequence":"additional","affiliation":[{"name":"Physiology and Psychology, Department of Neurological, Neuropsychological, Morphological and Movement Sciences, University of Verona; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0340004","series-title":"Cortex","first-page":"121","article-title":"Differences in matching persistence behavior during block design performance between older normal and brain-damaged persons: a process analysis","volume":"10","author":"Ben-Yishay","year":"1974"},{"key":"b2-0340004","series-title":"Exp Brain Res","first-page":"153","article-title":"New approaches to the study of human brain networks underlying spatial attention and related processes","volume":"206","author":"Driver","year":"2010"},{"key":"b3-0340004","series-title":"Acta Neurochir (Wien)","first-page":"1157","article-title":"Intra-operative direct electrical stimulations of the central nervous system: the Salp\u00eatri\u00e8re experience with 60 patients","volume":"141","author":"Duffau","year":"1999"},{"key":"b4-0340004","series-title":"J Neurooncol","first-page":"261","article-title":"Preand post-operative assessment of visuo-spatial functions in right hemisphere tumour patients: a pilot study","volume":"108","author":"Emanuele","year":"2012"},{"key":"b5-0340004","series-title":"Neurosurgery","first-page":"567","article-title":"Cortical localization of temporal lobe language sites in patients with gliomas","volume":"34","author":"Haglund","year":"1994"},{"key":"b6-0340004","series-title":"J Neurosurg","first-page":"369","article-title":"Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients","volume":"100","author":"Keles","year":"2004"},{"key":"b7-0340004","series-title":"Philos Trans R Soc Lond B Biol Sci","first-page":"1325","article-title":"Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events","volume":"354","author":"Mesulam","year":"1999"},{"key":"b8-0340004","series-title":"J Neurosurg","first-page":"316","article-title":"Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients","volume":"71","author":"Ojemann","year":"1989"},{"key":"b9-0340004","series-title":"J Neurosurg","first-page":"1010","article-title":"Resection of parietal lobe gliomas: incidence and evolution of neurological deficits in 28 consecutive patients correlated to the location and morphological characteristics of the tumor","volume":"103","author":"Russell","year":"2005"},{"key":"b10-0340004","series-title":"Behav Brain Res","first-page":"153","article-title":"Parietal cortex and spatial cognition","volume":"202","author":"Sack","year":"2009"},{"key":"b11-0340004","series-title":"N Engl J Med","first-page":"18","article-title":"Functional outcome after language mapping for glioma resection","volume":"358","author":"Sanai","year":"2008"},{"key":"b12-0340004","series-title":"J Neurosurg Anesthesiol","first-page":"209","article-title":"Eligibility criteria and psychological profiles in patient candidates for awake craniotomy: a pilot study","volume":"24","author":"Santini","year":"2012"},{"key":"b13-0340004","series-title":"Neurology","first-page":"509","article-title":"Line bisection and unilateral visual neglect in patients with neurologic impairment","volume":"30","author":"Schenkenberg","year":"1980"},{"key":"b14-0340004","series-title":"J Neurooncol","first-page":"541","article-title":"Cognitive effects of tumour and surgical treatment in glioma patients","volume":"103","author":"Talacchi","year":"2011"},{"key":"b15-0340004","series-title":"J Neurooncol","first-page":"417","article-title":"Surgical treatment of high-grade gliomas in motor areas. The impact of different supportive technologies: a 171-patient series","volume":"100","author":"Talacchi","year":"2010"},{"key":"b16-0340004","series-title":"Cereb Cortex","first-page":"2003","article-title":"Association between functional connectivity hubs and brain networks","volume":"21","author":"Tomasi","year":"2011"},{"key":"b17-0340004","series-title":"Ann N Y Acad Sci","first-page":"126","article-title":"Concepts and principles in the analysis of brain networks","volume":"1224","author":"Wig","year":"2011"},{"key":"b1-0340004","series-title":"Cortex","first-page":"121","article-title":"Differences in matching persistence behavior during block design performance between older normal and brain-damaged persons: a process analysis","volume":"10","author":"Ben-Yishay","year":"1974"},{"key":"b2-0340004","series-title":"Exp Brain Res","first-page":"153","article-title":"New approaches to the study of human brain networks underlying spatial attention and related processes","volume":"206","author":"Driver","year":"2010"},{"key":"b3-0340004","series-title":"Acta Neurochir (Wien)","first-page":"1157","article-title":"Intra-operative direct electrical stimulations of the central nervous system: the Salp\u00eatri\u00e8re experience with 60 patients","volume":"141","author":"Duffau","year":"1999"},{"key":"b4-0340004","series-title":"J Neurooncol","first-page":"261","article-title":"Preand post-operative assessment of visuo-spatial functions in right hemisphere tumour patients: a pilot study","volume":"108","author":"Emanuele","year":"2012"},{"key":"b5-0340004","series-title":"Neurosurgery","first-page":"567","article-title":"Cortical localization of temporal lobe language sites in patients with gliomas","volume":"34","author":"Haglund","year":"1994"},{"key":"b6-0340004","series-title":"J Neurosurg","first-page":"369","article-title":"Intraoperative subcortical stimulation mapping for hemispherical perirolandic gliomas located within or adjacent to the descending motor pathways: evaluation of morbidity and assessment of functional outcome in 294 patients","volume":"100","author":"Keles","year":"2004"},{"key":"b7-0340004","series-title":"Philos Trans R Soc Lond B Biol Sci","first-page":"1325","article-title":"Spatial attention and neglect: parietal, frontal and cingulate contributions to the mental representation and attentional targeting of salient extrapersonal events","volume":"354","author":"Mesulam","year":"1999"},{"key":"b8-0340004","series-title":"J Neurosurg","first-page":"316","article-title":"Cortical language localization in left, dominant hemisphere. An electrical stimulation mapping investigation in 117 patients","volume":"71","author":"Ojemann","year":"1989"},{"key":"b9-0340004","series-title":"J Neurosurg","first-page":"1010","article-title":"Resection of parietal lobe gliomas: incidence and evolution of neurological deficits in 28 consecutive patients correlated to the location and morphological characteristics of the tumor","volume":"103","author":"Russell","year":"2005"},{"key":"b10-0340004","series-title":"Behav Brain Res","first-page":"153","article-title":"Parietal cortex and spatial cognition","volume":"202","author":"Sack","year":"2009"},{"key":"b11-0340004","series-title":"N Engl J Med","first-page":"18","article-title":"Functional outcome after language mapping for glioma resection","volume":"358","author":"Sanai","year":"2008"},{"key":"b12-0340004","series-title":"J Neurosurg Anesthesiol","first-page":"209","article-title":"Eligibility criteria and psychological profiles in patient candidates for awake craniotomy: a pilot study","volume":"24","author":"Santini","year":"2012"},{"key":"b13-0340004","series-title":"Neurology","first-page":"509","article-title":"Line bisection and unilateral visual neglect in patients with neurologic impairment","volume":"30","author":"Schenkenberg","year":"1980"},{"key":"b14-0340004","series-title":"J Neurooncol","first-page":"541","article-title":"Cognitive effects of tumour and surgical treatment in glioma patients","volume":"103","author":"Talacchi","year":"2011"},{"key":"b15-0340004","series-title":"J Neurooncol","first-page":"417","article-title":"Surgical treatment of high-grade gliomas in motor areas. The impact of different supportive technologies: a 171-patient series","volume":"100","author":"Talacchi","year":"2010"},{"key":"b16-0340004","series-title":"Cereb Cortex","first-page":"2003","article-title":"Association between functional connectivity hubs and brain networks","volume":"21","author":"Tomasi","year":"2011"},{"key":"b17-0340004","series-title":"Ann N Y Acad Sci","first-page":"126","article-title":"Concepts and principles in the analysis of brain networks","volume":"1224","author":"Wig","year":"2011"}],"container-title":["Neurosurgical Focus"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus\/34\/2\/article-pE4.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus\/34\/2\/article-pE4.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus\/34\/2\/article-pE4.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T08:22:19Z","timestamp":1780734139000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus\/34\/2\/article-pE4.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2013,2]]},"references-count":34,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/2012.12.focus12358","relation":{},"ISSN":["1092-0684"],"issn-type":[{"value":"1092-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,2]]}}}