{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,6,6]],"date-time":"2026-06-06T09:01:29Z","timestamp":1780736489260,"version":"3.54.1"},"reference-count":44,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2013,3]]},"abstract":"\n Object<\/jats:title>\n Microvascular decompression (MVD) of the facial nerve is an effective treatment for patients with hemifacial spasm. Intraoperative monitoring of brainstem auditory evoked potentials (BAEPs) during MVD can reduce the incidence of hearing loss. In this study the authors' goal was to evaluate changes in interpeak latencies (IPLs) of Waves I\u2013V, Waves III\u2013V, and Waves I\u2013III of BAEP Waveforms I, III, and V during MVD and correlate them with postoperative hearing loss. To date, no such study has been performed. Hearing loss is defined as nonuseful hearing (Class C\/D), which is a pure tone average of more than 50 dB and\/or speech discrimination score of less than 50%.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n The authors performed a retrospective analysis of IPLs of BAEPs in 93 patients who underwent intraoperative BAEP monitoring during MVD. Patients who did not have hearing loss were in Class A\/B and those who had hearing loss were in Class C\/D.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n Binary logistic regression analysis of independent IPL variables was performed. A maximum change in IPLs of Waves I\u2013III and Waves I\u2013V and on-skin change in IPLs of Waves I\u2013V increases the odds of hearing loss. However, on adjusting the same variables for loss of response, change in IPLs did not increase the odds of hearing loss.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n Changes in IPL measurements did not increase the odds of postoperative hearing loss. This information might be helpful in evaluating the value of IPLs as alarm criteria during MVD to prevent hearing loss.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2012.12.focus12393","type":"journal-article","created":{"date-parts":[[2013,3,1]],"date-time":"2013-03-01T21:41:26Z","timestamp":1362174086000},"page":"E6","source":"Crossref","is-referenced-by-count":7,"title":["Analysis of interpeak latencies of brainstem auditory evoked potential waveforms during microvascular decompression of cranial nerve VII for hemifacial spasm"],"prefix":"10.3171","volume":"34","author":[{"given":"Parthasarathy D.","family":"Thirumala","sequence":"first","affiliation":[{"name":"Departments of Neurological Surgery,"},{"name":"Neurology, University of Pittsburgh Medical Center, Pittsburgh, Pennsylvania"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Preethi","family":"Ilangovan","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Miguel","family":"Habeych","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Donald J.","family":"Crammond","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey","family":"Balzer","sequence":"additional","affiliation":[{"name":"Departments of Neurological Surgery,"},{"name":"Neuroscience, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0340006","series-title":"J Neurosurg","first-page":"201","article-title":"Microvascular decompression for hemifacial spasm","volume":"82","author":"Barker","year":"1995"},{"key":"b2-0340006","series-title":"Evoked Potentials in Clinical Medicine","first-page":"199","article-title":"Brain stem auditory evoked potentials: interpretation","author":"Chiappa","year":"1997"},{"key":"b3-0340006","series-title":"Otolaryngol Head Neck Surg","first-page":"179","article-title":"Guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma)","volume":"113","author":"Committee on Hearing and Equilibrium","year":"1995"},{"key":"b4-0340006","series-title":"Acta Neurochir (Wien)","first-page":"681","article-title":"Correlation between latency and amplitude of peak V in the brainstem auditory evoked potentials: intraoperative recordings in microvascular decompression operations","volume":"140","author":"Hatayama","year":"1998"},{"key":"b5-0340006","series-title":"J Neurosurg","first-page":"321","article-title":"Etiology and definitive microsurgical treatment of hemifacial spasm. Operative techniques and results in 47 patients","volume":"47","author":"Jannetta","year":"1977"},{"key":"b6-0340006","series-title":"J Clin Neurosci","first-page":"1335","article-title":"Prognostic value of intra-operative lateral spread response monitoring during microvascular decompression in patients with hemifacial spasm","volume":"15","author":"Joo","year":"2008"},{"key":"b7-0340006","series-title":"J Clin Neurophysiol","first-page":"396","article-title":"Mechanisms of intraoperative brainstem auditory evoked potential changes","volume":"19","author":"Legatt","year":"2002"},{"key":"b8-0340006","series-title":"Neurol Clin","first-page":"681","article-title":"The anatomic and physiologic bases of brain stem auditory evoked potentials","volume":"6","author":"Legatt","year":"1988"},{"key":"b9-0340006","series-title":"Neurosurgery","first-page":"496","article-title":"Brain stem auditory evoked potentials in posterior circulation surgery","volume":"12","author":"Little","year":"1983"},{"key":"b10-0340006","series-title":"J Clin Neurophysiol","first-page":"319","article-title":"Brainstem auditory evoked potentials","volume":"11","author":"Markand","year":"1994"},{"key":"b11-0340006","series-title":"Neurochirurgie","first-page":"527","article-title":"[Microsurgical vascular decompression for hemifacial spasm. Follow-up over one year, clinical results and prognostic factors. Study of a series of 100 cases.]","volume":"49","author":"Marneffe","year":"2003"},{"key":"b12-0340006","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1375","article-title":"A reappraisal of the value of lateral spread response monitoring in the treatment of hemifacial spasm by microvascular decompression","volume":"80","author":"Neves","year":"2009"},{"key":"b13-0340006","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1165","article-title":"Patterns of hearing loss after microvascular decompression for hemifacial spasm","volume":"80","author":"Park","year":"2009"},{"key":"b14-0340006","series-title":"Neurosurgery","first-page":"97","article-title":"Brainstem auditory evoked potential monitoring during microvascular decompression for hemifacial spasm: intraoperative brainstem auditory evoked potential changes and warning values to prevent hearing loss\u2014prospective study in a consecutive series of 84 patients","volume":"54","author":"Polo","year":"2004"},{"key":"b15-0340006","series-title":"Neurology","first-page":"187","article-title":"Intraoperative brainstem auditory evoked potentials: significant decrease in postoperative morbidity","volume":"39","author":"Radtke","year":"1989"},{"key":"b16-0340006","series-title":"Laryngoscope","first-page":"591","article-title":"Hearing preservation in microvascular decompression for trigeminal neuralgia","volume":"109","author":"Rizvi","year":"1999"},{"key":"b17-0340006","series-title":"Neurosurgery","first-page":"712","article-title":"Microvascular decompression to treat hemifacial spasm: long-term results for a consecutive series of 143 patients","volume":"50","author":"Samii","year":"2002"},{"key":"b18-0340006","series-title":"Neurosurgery","first-page":"694","article-title":"Detailed analysis of intraoperative changes monitoring brain stem acoustic evoked potentials","volume":"22","author":"Schramm","year":"1988"},{"key":"b19-0340006","series-title":"Acta Neurochir (Wien)","first-page":"1019","article-title":"Microvascular decompression for primary hemifacial spasm. Importance of intraoperative neurophysiological monitoring","volume":"147","author":"Sindou","year":"2005"},{"issue":"1 Suppl Operative","key":"b20-0340006","series-title":"Neurosurgery","first-page":"ons64","article-title":"Somatosensory evoked potential monitoring during endoscopic endonasal approach to skull base surgery: analysis of observed changes","volume":"69","author":"Thirumala","year":"2011"},{"key":"b21-0340006","series-title":"J Clin Neurophysiol","first-page":"56","article-title":"Microvascular decompression for hemifacial spasm: evaluating outcome prognosticators including the value of intraoperative lateral spread response monitoring and clinical characteristics in 293 patients","volume":"28","author":"Thirumala","year":"2011"},{"key":"b22-0340006","series-title":"J Bone Joint Surg Br","first-page":"126","article-title":"Experimental stretch neuropathy. Changes in nerve conduction under tension","volume":"74","author":"Wall","year":"1992"},{"key":"b1-0340006","series-title":"J Neurosurg","first-page":"201","article-title":"Microvascular decompression for hemifacial spasm","volume":"82","author":"Barker","year":"1995"},{"key":"b2-0340006","series-title":"Evoked Potentials in Clinical Medicine","first-page":"199","article-title":"Brain stem auditory evoked potentials: interpretation","author":"Chiappa","year":"1997"},{"key":"b3-0340006","series-title":"Otolaryngol Head Neck Surg","first-page":"179","article-title":"Guidelines for the evaluation of hearing preservation in acoustic neuroma (vestibular schwannoma)","volume":"113","author":"Committee on Hearing and Equilibrium","year":"1995"},{"key":"b4-0340006","series-title":"Acta Neurochir (Wien)","first-page":"681","article-title":"Correlation between latency and amplitude of peak V in the brainstem auditory evoked potentials: intraoperative recordings in microvascular decompression operations","volume":"140","author":"Hatayama","year":"1998"},{"key":"b5-0340006","series-title":"J Neurosurg","first-page":"321","article-title":"Etiology and definitive microsurgical treatment of hemifacial spasm. 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Follow-up over one year, clinical results and prognostic factors. Study of a series of 100 cases.]","volume":"49","author":"Marneffe","year":"2003"},{"key":"b12-0340006","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1375","article-title":"A reappraisal of the value of lateral spread response monitoring in the treatment of hemifacial spasm by microvascular decompression","volume":"80","author":"Neves","year":"2009"},{"key":"b13-0340006","series-title":"J Neurol Neurosurg Psychiatry","first-page":"1165","article-title":"Patterns of hearing loss after microvascular decompression for hemifacial spasm","volume":"80","author":"Park","year":"2009"},{"key":"b14-0340006","series-title":"Neurosurgery","first-page":"97","article-title":"Brainstem auditory evoked potential monitoring during microvascular decompression for hemifacial spasm: intraoperative brainstem auditory evoked potential changes and warning values to prevent hearing loss\u2014prospective study in a consecutive series of 84 patients","volume":"54","author":"Polo","year":"2004"},{"key":"b15-0340006","series-title":"Neurology","first-page":"187","article-title":"Intraoperative brainstem auditory evoked potentials: significant decrease in postoperative morbidity","volume":"39","author":"Radtke","year":"1989"},{"key":"b16-0340006","series-title":"Laryngoscope","first-page":"591","article-title":"Hearing preservation in microvascular decompression for trigeminal neuralgia","volume":"109","author":"Rizvi","year":"1999"},{"key":"b17-0340006","series-title":"Neurosurgery","first-page":"712","article-title":"Microvascular decompression to treat hemifacial spasm: long-term results for a consecutive series of 143 patients","volume":"50","author":"Samii","year":"2002"},{"key":"b18-0340006","series-title":"Neurosurgery","first-page":"694","article-title":"Detailed analysis of intraoperative changes monitoring brain stem acoustic evoked potentials","volume":"22","author":"Schramm","year":"1988"},{"key":"b19-0340006","series-title":"Acta Neurochir (Wien)","first-page":"1019","article-title":"Microvascular decompression for primary hemifacial spasm. 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