{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,4]],"date-time":"2026-11-04T22:17:47Z","timestamp":1793830667903,"version":"4.6.1"},"reference-count":8,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2012,7]]},"abstract":"<jats:p>The authors report the case of a 55-year-old man who presented with acute motor-sensory axonal neuropathy (AMSAN), a variant of Guillain-Barr\u00e9 syndrome with a poor prognosis, immediately after surgery for resection of a cervical chondroma. A misdiagnosis of spinal cord shock due to an acute surgical or vascular postoperative complication was initially made in this patient. Nevertheless, there was continuous transient improvement that was followed by progressive worsening, and further investigation was necessary. The diagnosis of AMSAN, associated with acute colitis caused by <jats:italic>Helicobacter pylori<\/jats:italic>, was made based on neurophysiological examinations and colonoscopy. Interestingly, the patient also developed nephrotic syndrome, which was thought to be a further complication of the autoimmune reaction. Delayed administration of immunoglobulins (400 mg\/kg\/day), mesalazine (800 mg 3\u00d7\/day), and meropenem (3 g\/day) was used to treat the <jats:italic>Helicobacter<\/jats:italic> infection and the autoimmune reaction, leading to restoration of renal function and slight neurological improvement. The patient's general condition and neurological status improved slightly, but he remained seriously disabled (Frankel Grade C). This case demonstrates that a new onset of neurological symptoms in the early postoperative period after spine surgery could be related to causes other than iatrogenic myelopathy, and that an early diagnosis can reduce neurological sequelae, leading to a better outcome.<\/jats:p>","DOI":"10.3171\/2012.4.spine11932","type":"journal-article","created":{"date-parts":[[2012,5,4]],"date-time":"2012-05-04T15:29:46Z","timestamp":1336145386000},"page":"82-85","source":"Crossref","is-referenced-by-count":13,"title":["Acute motor-sensory axonal neuropathy after cervical spine surgery"],"prefix":"10.3171","volume":"17","author":[{"given":"Massimo","family":"Miscusi","sequence":"first","affiliation":[{"name":"Departments of Medico-Surgical Sciences and Biotechnologies, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"Curr\u00e0","sequence":"additional","affiliation":[{"name":"Departments of Medico-Surgical Sciences and Biotechnologies, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Carlo Della","family":"Rocca","sequence":"additional","affiliation":[{"name":"Departments of Medico-Surgical Sciences and Biotechnologies, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Paolo","family":"Missori","sequence":"additional","affiliation":[{"name":"Neurology and Psychiatry, Sapienza University of Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vincenzo","family":"Petrozza","sequence":"additional","affiliation":[{"name":"Departments of Medico-Surgical Sciences and Biotechnologies, and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-spine11932","series-title":"Ann Indian Acad Neurol","doi-asserted-by":"publisher","first-page":"98","DOI":"10.4103\/0972-2327.82793","article-title":"Clinical features and prognosis with Guillain-Barr\u00e9 syndrome","volume":"14","author":"Akbayram","year":"2011"},{"key":"b2-spine11932","series-title":"Eur J Neurol","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1111\/j.1468-1331.2010.03095.x","article-title":"Neurologic disorders associated with inflammatory bowel disease","volume":"18","author":"Benavente","year":"2011"},{"key":"b3-spine11932","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"605","DOI":"10.3171\/2011.8.SPINE1159","article-title":"The acute motor-sensory axonal neuropathy variant of Guillain-Barr\u00e9 syndrome after thoracic spine surgery. 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