{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,11]],"date-time":"2025-11-11T22:07:08Z","timestamp":1762898828357},"reference-count":11,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2012,8]]},"abstract":"<jats:p>The authors report on a case of histiocytic sarcoma (HS) in a pediatric patient presenting with a solitary tumor in the cerebellum, with the aim of providing insight into primary HS in the CNS, which is especially rare. A 17-month-old Japanese girl presented with a 2-week history of progressive gait disturbance. Brain MRI revealed a 4.7 \u00d7 4.3 \u00d7 4.3\u2013cm well-demarcated solitary mass in the right hemisphere of the cerebellum, initially suggestive of medulloblastoma, ependymoma, or anaplastic astrocytoma. On intraoperative inspection the cerebellar tumor showed intensive dural attachment and was subtotally removed. Histological and immunohistochemical findings were consistent with HS. The patient subsequently received chemotherapy, and her preoperative neurological symptoms improved. Primary HS in the CNS usually demonstrates an aggressive clinical course and is currently considered to have a poor prognosis. The possibility of this rare tumor should be included in the differential diagnosis of localized cerebellar tumors in the pediatric age group.<\/jats:p>","DOI":"10.3171\/2012.5.peds11270","type":"journal-article","created":{"date-parts":[[2012,6,29]],"date-time":"2012-06-29T14:05:48Z","timestamp":1340978748000},"page":"126-129","source":"Crossref","is-referenced-by-count":16,"title":["Primary cerebellar histiocytic sarcoma in a 17-month-old girl"],"prefix":"10.3171","volume":"10","author":[{"given":"Kiyoshi","family":"Gomi","sequence":"first","affiliation":[{"name":"Divisions of Pathology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mio","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Divisions of Pathology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Yoshida","sequence":"additional","affiliation":[{"name":"Divisions of Pathology,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Susumu","family":"Ito","sequence":"additional","affiliation":[{"name":"Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Masaki","family":"Sonoda","sequence":"additional","affiliation":[{"name":"Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Fuminori","family":"Iwasaki","sequence":"additional","affiliation":[{"name":"Oncology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tetsu","family":"Niwa","sequence":"additional","affiliation":[{"name":"Radiology, Kanagawa Children's Medical Center, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noriko","family":"Aida","sequence":"additional","affiliation":[{"name":"Radiology, Kanagawa Children's Medical Center, Yokohama, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hisato","family":"Kigasawa","sequence":"additional","affiliation":[{"name":"Oncology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yukichi","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Divisions of Pathology,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-peds11270","series-title":"Arch Pathol Lab Med","doi-asserted-by":"publisher","first-page":"301","DOI":"10.5858\/2007-131-301-PCNSHS","article-title":"Primary central nervous system histiocytic sarcoma with relapse to mediastinum: a case report and review of the literature","volume":"131","author":"Cao","year":"2007"},{"key":"b2-peds11270","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"1372","DOI":"10.1097\/00000478-200111000-00004","article-title":"Primary histiocytic lymphoma of the central nervous system: a neoplasm frequently overshadowed by a prominent inflammatory component","volume":"25","author":"Cheuk","year":"2001"},{"key":"b3-peds11270","series-title":"Eur J Cancer","doi-asserted-by":"publisher","first-page":"2939","DOI":"10.1016\/j.ejca.2006.06.021","article-title":"High-grade glioma in children under 5 years of age: a chemotherapy only approach with the BBSFOP protocol","volume":"42","author":"Dufour","year":"2006"},{"key":"b4-peds11270","series-title":"Am J Surg Pathol","doi-asserted-by":"publisher","first-page":"1133","DOI":"10.1097\/01.pas.0000131541.95394.23","article-title":"Extranodal histiocytic sarcoma: clinicopathologic analysis of 14 cases of a rare epithelioid malignancy","volume":"28","author":"Hornick","year":"2004"},{"key":"b5-peds11270","series-title":"Pediatr Blood Cancer","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1002\/pbc.21252","article-title":"Central nervous system juvenile xanthogranuloma with malignant transformation","volume":"50","author":"Orsey","year":"2008"},{"key":"b6-peds11270","series-title":"Brain Pathol","first-page":"386","article-title":"Meningeal tumors of childhood and infancy. 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