{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:33:43Z","timestamp":1783776823360,"version":"3.55.0"},"reference-count":25,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2012,9]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Rising numbers of MRI studies performed during evaluations for pediatric disorders have contributed to a significant increase in the number of incidentally found brain tumors. Currently, there is very little literature on the nature of and the preferred treatment for these incidental brain tumors. In this paper the authors review their experience diagnosing and treating these lesions in children as well as the current literature on this topic.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Records from 2 centers were reviewed for incidentally found brain tumors, treatment approaches, and outcomes for both surgical and nonsurgical cohorts.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Forty-seven children (30 males and 17 females) with a mean age of 8.6 years were found to have incidental brain lesions suspected to be neoplasms. Twenty-five underwent surgery and 22 were observed. Two children in the observation group required surgery at a later stage. Tumor pathology in 24 patients was benign. Only 3 patients had high-grade tumors. All nonsurgically treated lesions were presumed to be low-grade tumors and were followed up for 25 \u00b1 20 months.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The discovery of incidental brain tumors on MRI in children poses an increasing challenge. Additional studies are needed to determine the significance as well as the optimal management strategies in this situation.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2012.6.peds11451","type":"journal-article","created":{"date-parts":[[2012,7,21]],"date-time":"2012-07-21T00:19:34Z","timestamp":1342829974000},"page":"168-174","source":"Crossref","is-referenced-by-count":22,"title":["Pediatric incidental brain tumors: a growing treatment dilemma"],"prefix":"10.3171","volume":"10","author":[{"given":"Jonathan","family":"Roth","sequence":"first","affiliation":[{"name":"Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel-Aviv Medical Center, Tel-Aviv, Israel; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert F.","family":"Keating","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Pediatrics, Children's National Medical Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John S.","family":"Myseros","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Pediatrics, Children's National Medical Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Amanda L.","family":"Yaun","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Pediatrics, Children's National Medical Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Suresh N.","family":"Magge","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and Pediatrics, Children's National Medical Center, Washington, DC"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Shlomi","family":"Constantini","sequence":"additional","affiliation":[{"name":"Department of Pediatric Neurosurgery, Dana Children's Hospital, Tel-Aviv Medical Center, Tel-Aviv, Israel; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-peds11451","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"758","DOI":"10.1007\/s003810050467","article-title":"Epidemiologic impact of children with brain tumors","volume":"15","author":"Bleyer","year":"1999"},{"key":"b2-peds11451","series-title":"J Neurooncol","doi-asserted-by":"publisher","first-page":"589","DOI":"10.1007\/s11060-011-0695-1","article-title":"Incidental brain lesions in children: to treat or not to treat?","volume":"106","author":"Bredlau","year":"2012"},{"key":"b3-peds11451","series-title":"Primary Brain Tumors in the United States Statistical Report 2000\u20132004 (Years of Data Collected)","author":"Central Brain Tumor Registry of the United States","year":"2008"},{"key":"b4-peds11451","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"550","DOI":"10.1016\/j.surneu.2004.07.049","article-title":"Incidental findings in brain computed tomography scans of 3000 head trauma patients","volume":"63","author":"Eskandary","year":"2005"},{"key":"b5-peds11451","series-title":"Pediatr Radiol","doi-asserted-by":"publisher","first-page":"1086","DOI":"10.1007\/s00247-005-1546-z","article-title":"Spontaneous regression of residual low-grade cerebellar pilocytic astrocytomas in children","volume":"35","author":"Gunny","year":"2005"},{"key":"b6-peds11451","series-title":"J Child Neurol","doi-asserted-by":"publisher","first-page":"1511","DOI":"10.1177\/0883073810370622","article-title":"Are incidental findings on brain magnetic resonance images in children merely incidental?","volume":"25","author":"Gupta","year":"2010"},{"key":"b7-peds11451","series-title":"Nat Clin Pract Neurol","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1038\/ncpneuro0119","article-title":"\u2018Pandora's box\u2019 of incidental findings in brain imaging research","volume":"2","author":"Illes","year":"2006"},{"key":"b8-peds11451","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"384","DOI":"10.1212\/01.wnl.0000280469.17461.94","article-title":"Practical approaches to incidental findings in brain imaging research","volume":"70","author":"Illes","year":"2008"},{"key":"b9-peds11451","series-title":"Science","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1126\/science.1124665","article-title":"Ethics. 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