{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T14:27:59Z","timestamp":1787063279168,"version":"build-2736575974"},"reference-count":28,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2013,3]]},"abstract":"<jats:sec>\n                    <jats:title>Object<\/jats:title>\n                    <jats:p>In this paper the authors describe a modified far-lateral transcondylar approach to remove hypoglossal neurilemmomas (HGNs).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Methods<\/jats:title>\n                    <jats:p>Between September 2008 and June 2011, 11 consecutive patients with HGNs underwent tumor removal via a modified far-lateral transcondylar approach. The average age at presentation, tumor characteristics, cranial nerve (CN) deficits, and outcomes were assessed. The modified far-lateral transcondylar approach comprises several important steps. The first step is to remove the limited posterior aspect of the condylar facet to open the hypoglossal canal. The second step is to expose the posterior arch and the transverse process of C-1. A fat layer covers the venous plexus of the vertebral artery, and careful dissection along this surface of the fat layer is important to protect the vertebral artery from damage. The neck muscles are dissected caudally to expose the extracranial component of the tumor, which is located in front of the transverse process of C-1.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Results<\/jats:title>\n                    <jats:p>Eleven cases of HGNs were treated during the study period. The mean patient age was 47.4 \u00b1 8.9 years (range 31\u201359 years); there were 3 men and 8 women. The mean follow-up period was 14.1 \u00b1 9 months. All patients presented with hypoglossal nerve deficits; other commonly observed deficits included glossopharyngeal and vestibular\/cochlear nerve deficits. Gross-total resection of the tumor was achieved in 10 patients. A subtotal resection of the tumor was achieved in the remaining patient. Two patients had transient postoperative facial nerve palsies, 1 patient developed a new CN XI palsy postoperatively, and 5 patients experienced transient hoarseness and difficulty swallowing. Two patients required a tracheotomy because they demonstrated dysfunction of the caudal CNs and subsequently developed postoperative pneumonia. Postoperatively, 5 patients required the temporary placement of a nasogastric feeding tube. There were no surgery-related deaths in this series.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>Conclusions<\/jats:title>\n                    <jats:p>The modified far-lateral transcondylar approach is an effective treatment for HGNs, yielding a high total tumor removal rate with an acceptable rate of morbidity.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2012.9.jns12176","type":"journal-article","created":{"date-parts":[[2012,10,19]],"date-time":"2012-10-19T10:14:57Z","timestamp":1350641697000},"page":"657-668","source":"Crossref","is-referenced-by-count":9,"title":["Using a modified far-lateral approach to remove hypoglossal neurilemmomas: notes on technique"],"prefix":"10.3171","volume":"118","author":[{"given":"Xinru","family":"Xiao","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zhen","family":"Wu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Liwei","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guijun","family":"Jia","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jie","family":"Tang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guolu","family":"Meng","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Junting","family":"Zhang","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns12176","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"526","DOI":"10.1016\/j.surneu.2004.07.045","article-title":"Dumbbell-shaped hypoglossal schwannoma in an elderly woman: a clinical dilemma","volume":"63","author":"Aihara","year":"2005"},{"key":"b2-jns12176","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"920","DOI":"10.3171\/jns.2005.103.5.0920","article-title":"Endoscope-assisted microsurgical resection of an intraneural ganglion cyst of the hypoglossal nerve","volume":"103","author":"Baldauf","year":"2005"},{"key":"b3-jns12176","series-title":"Acta Otolaryngol","doi-asserted-by":"publisher","first-page":"1005","DOI":"10.1080\/00016480601110261","article-title":"Base of tongue neurilemmoma: excision by transoral laser microsurgery","volume":"127","author":"Ballesteros","year":"2007"},{"key":"b4-jns12176","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"592","DOI":"10.1136\/jnnp.36.4.592","article-title":"Dumbbell neurinoma of the hypoglossal nerve","volume":"36","author":"Bartal","year":"1973"},{"key":"b5-jns12176","series-title":"Neurosurg Rev","doi-asserted-by":"publisher","first-page":"299","DOI":"10.1007\/s10143-008-0143-7","article-title":"Morphometric three-dimensional computed tomography anatomy of the hypoglossal canal","volume":"31","author":"Bulsara","year":"2008"},{"key":"b6-jns12176","series-title":"J Craniofac Surg","doi-asserted-by":"publisher","first-page":"261","DOI":"10.1097\/SCS.0b013e3181c5a37c","article-title":"Hypoglossal schwannoma presenting only with headache","volume":"21","author":"Edizer","year":"2010"},{"key":"b7-jns12176","series-title":"Rev Laryngol Otol Rhinol (Bord)","first-page":"189","article-title":"A schwannoma of the hypoglossal nerve presenting as a malignant tumour of the oral floor","volume":"130","author":"Fakhry","year":"2009"},{"key":"b8-jns12176","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"605","DOI":"10.1007\/s00701-008-1498-1","article-title":"Fatal delayed post-operative cerebral venous thrombosis after excision of hypoglossal nerve schwannoma","volume":"150","author":"Garg","year":"2008"},{"key":"b9-jns12176","series-title":"Int J Oral Maxillofac Surg","doi-asserted-by":"publisher","first-page":"759","DOI":"10.1016\/j.ijom.2007.02.009","article-title":"Isolated hypoglossal nerve palsy due to a vascular anomaly","volume":"36","author":"Graham","year":"2007"},{"key":"b10-jns12176","series-title":"Laryngoscope","doi-asserted-by":"publisher","first-page":"1648","DOI":"10.1097\/00005537-200409000-00027","article-title":"Infratemporal fossa approach to the hypoglossal canal: practical landmarks for elusive anatomy","volume":"114","author":"Hadley","year":"2004"},{"key":"b11-jns12176","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"E212","DOI":"10.1227\/01.NEU.0000347006.02222.CB","article-title":"A cylindrical extracranial cranial base neurilemmoma of the hypoglossal nerve: a rare tumor with a rare localization: case report","volume":"65","author":"Heiroth","year":"2009"},{"key":"b12-jns12176","series-title":"Neurol Med Chir (Tokyo)","doi-asserted-by":"publisher","first-page":"489","DOI":"10.2176\/nmc.40.489","article-title":"Hypoglossal neurinoma\u2014two case reports","volume":"40","author":"Hoshi","year":"2000"},{"key":"b13-jns12176","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"575","DOI":"10.1007\/s00701-009-0284-7","article-title":"Surgical approach for hypoglossal schwannomas to prevent deformity of the atlantooccipital joint","volume":"151","author":"Ichimura","year":"2009"},{"key":"b14-jns12176","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"1053","DOI":"10.1016\/j.jocn.2009.09.040","article-title":"Intraoperative monitoring during surgery for hypoglossal schwannoma","volume":"17","author":"Ishikawa","year":"2010"},{"key":"b15-jns12176","series-title":"Surg Radiol Anat","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1007\/s00276-008-0455-x","article-title":"The microsurgical anatomy of the hypoglossal canal","volume":"31","author":"Karasu","year":"2009"},{"key":"b16-jns12176","series-title":"J Laryngol Otol","doi-asserted-by":"publisher","first-page":"803","DOI":"10.1017\/S0022215107006275","article-title":"Isolated hypoglossal nerve palsy: a harbinger of malignancy","volume":"121","author":"Khoo","year":"2007"},{"key":"b17-jns12176","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"296","DOI":"10.1055\/s-2007-984385","article-title":"A case of intracranial hypoglossal schwannoma without hypoglossal nerve palsy: operative view of the preserved rostral trunk","volume":"50","author":"Kikkawa","year":"2007"},{"key":"b18-jns12176","series-title":"Neurol Med Chir (Tokyo)","doi-asserted-by":"publisher","first-page":"384","DOI":"10.2176\/nmc.36.384","article-title":"Intracranial hypoglossal neurinoma without preoperative hypoglossal nerve paresis\u2014case report","volume":"36","author":"Kobayashi","year":"1996"},{"issue":"Suppl 1","key":"b19-jns12176","series-title":"Surg Neurol","first-page":"S1:34","article-title":"Extradural dumbbell neurilemmoma of the hypoglossal nerve: a case report with review of the literature","volume":"70","author":"Kuo","year":"2008"},{"key":"b20-jns12176","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"837","DOI":"10.1007\/s00701-009-0226-4","article-title":"Hypoglossal schwannoma-successful reinnervation and functional recovery of the tongue following tumour removal and nerve grafting","volume":"151","author":"Mathiesen","year":"2009"},{"key":"b21-jns12176","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"583","DOI":"10.1227\/00006123-198904000-00016","article-title":"Intracranial hypoglossal neurinoma with extracranial extension: review and case report","volume":"24","author":"Odake","year":"1989"},{"issue":"Suppl 1","key":"b22-jns12176","series-title":"Stereotact Funct Neurosurg","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1159\/000099775","article-title":"Acoustic neurilemmomas with macrocysts treated with gamma knife radiosurgery","volume":"66","author":"Pendl","year":"1996"},{"key":"b23-jns12176","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"949","DOI":"10.1007\/s00701-007-1154-9","article-title":"Neurinoma of the hypoglossal nerve in the submandibular space: case report and review of the literature","volume":"149","author":"Piccirilli","year":"2007"},{"key":"b24-jns12176","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"522","DOI":"10.1212\/01.wnl.0000197790.30329.96","article-title":"Hypoglossal nerve paralysis caused by high cervical epidural abscess","volume":"66","author":"Srivastava","year":"2006"},{"key":"b25-jns12176","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"374","DOI":"10.1055\/s-2007-993206","article-title":"Intradural microsurgery and extradural gamma knife surgery for hypoglossal schwannoma: case report and review of the literature","volume":"50","author":"Tucker","year":"2007"},{"key":"b26-jns12176","series-title":"J Laryngol Otol","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1258\/002221504772784649","article-title":"Extracranial internal carotid artery aneurysm presenting as symptomatic hypoglossal and glossopharyngeal nerve paralysis","volume":"118","author":"Wilding","year":"2004"},{"key":"b27-jns12176","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1113","DOI":"10.3171\/jns.2002.96.6.1113","article-title":"Detailed anatomy of the intracranial segment of the hypoglossal nerve: neurovascular relationships and landmarks on magnetic resonance imaging sequences","volume":"96","author":"Yousry","year":"2002"},{"issue":"5 Suppl","key":"b28-jns12176","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"456","DOI":"10.3171\/jns.2002.97.supplement_5.0456","article-title":"Gamma knife radiosurgery for jugular foramen schwannomas","volume":"97","author":"Zhang","year":"2002"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/118\/3\/article-p657.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/118\/3\/article-p657.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/118\/3\/article-p657.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,8,14]],"date-time":"2022-08-14T13:54:58Z","timestamp":1660485298000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/118\/3\/article-p657.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2013,3]]},"references-count":28,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2012.9.jns12176","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,3]]}}}