{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,22]],"date-time":"2026-07-22T21:26:39Z","timestamp":1784755599151,"version":"3.55.0"},"reference-count":15,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2014,2]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The sella turcica usually appears partially empty in MR images obtained from patients with chronic elevation of intracranial pressure. The authors measured the size of the sella turcica to determine if enlargement of the pituitary fossa explains the partially empty sella associated with pseudotumor cerebri.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The medical records from 2005 to 2011 of a single neuro-ophthalmologist were searched to identify consecutive patients with pseudotumor cerebri. Age-matched control patients were selected from the same practice. The sella turcica and pituitary gland were measured on sagittal T1-weighted MR images.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Measurements were obtained for 48 patients with pseudotumor cerebri and 48 controls. The cross-sectional area of the sella was 38% greater in the patients with pseudotumor cerebri, with only a slight reduction in mean pituitary gland size.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Chronic elevation of intracranial pressure is associated with bony enlargement of the sella turcica. Enlargement of the sella turcica contributes to its partially empty appearance.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2013.10.jns131265","type":"journal-article","created":{"date-parts":[[2013,12,6]],"date-time":"2013-12-06T15:16:13Z","timestamp":1386342973000},"page":"538-542","source":"Crossref","is-referenced-by-count":35,"title":["Enlargement of the sella turcica in pseudotumor cerebri"],"prefix":"10.3171","volume":"120","author":[{"given":"Sung-eun E.","family":"Kyung","sequence":"first","affiliation":[{"name":"Department of Ophthalmology, School of Medicine, University of Dankook at Cheonan, South Korea; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"James V.","family":"Botelho","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology, Neurology, and Physiology, University of California, San Francisco, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jonathan C.","family":"Horton","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology, Neurology, and Physiology, University of California, San Francisco, California"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns131265","series-title":"Ophthalmology","doi-asserted-by":"publisher","first-page":"1686","DOI":"10.1016\/S0161-6420(98)99039-X","article-title":"Magnetic resonance imaging in pseudotumor cerebri","volume":"105","author":"Brodsky","year":"1998"},{"key":"b2-jns131265","series-title":"AJR Am J Roentgenol","doi-asserted-by":"publisher","first-page":"797","DOI":"10.2214\/ajr.148.4.797","article-title":"MR imaging of pituitary adenoma: CT, clinical, and surgical correlation","volume":"148","author":"Davis","year":"1987"},{"key":"b3-jns131265","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"1492","DOI":"10.1212\/01.WNL.0000029570.69134.1B","article-title":"Diagnostic criteria for idiopathic intracranial hypertension","volume":"59","author":"Friedman","year":"2002"},{"key":"b4-jns131265","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"931","DOI":"10.1148\/90.5.931","article-title":"The \u201cempty\u201d sella turcica\u2014a manifestation of the intrasellar subarachnoid space","volume":"90","author":"Kaufman","year":"1968"},{"key":"b5-jns131265","series-title":"Clin Anat","doi-asserted-by":"publisher","first-page":"629","DOI":"10.1002\/ca.20984","article-title":"Nasal, sellar, and sphenoid sinus measurements in relation to pituitary surgery","volume":"23","author":"Lazaridis","year":"2010"},{"key":"b6-jns131265","series-title":"Clin Radiol","doi-asserted-by":"publisher","first-page":"656","DOI":"10.1016\/j.crad.2011.12.002","article-title":"Accuracy of brain imaging in the diagnosis of idiopathic intracranial hypertension","volume":"67","author":"Maralani","year":"2012"},{"key":"b7-jns131265","series-title":"Hum Brain Mapp","first-page":"1751","article-title":"Scan-rescan reliability of subcortical brain volumes derived from automated segmentation","volume":"31","author":"Morey","year":"2010"},{"key":"b8-jns131265","series-title":"J Neuroimaging","doi-asserted-by":"publisher","first-page":"74","DOI":"10.1111\/j.1552-6569.2006.00069.x","article-title":"Validation of intracranial area as a surrogate measure of intracranial volume when using clinical MRI","volume":"17","author":"Nandigam","year":"2007"},{"key":"b9-jns131265","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"207","DOI":"10.1148\/radiology.170.1.2909098","article-title":"Idiopathic intracranial hypertension (pseudotumor cerebri): MR imaging","volume":"170","author":"Silbergleit","year":"1989"},{"key":"b10-jns131265","series-title":"Rev Neurol Dis","first-page":"e56","article-title":"An update on idiopathic intracranial hypertension","volume":"7","author":"Thurtell","year":"2010"},{"key":"b11-jns131265","series-title":"Neurol Clin","doi-asserted-by":"publisher","first-page":"783","DOI":"10.1016\/S0733-8619(18)30948-4","article-title":"Neuroimaging in neuroendocrine diseases","volume":"4","author":"Weisberg","year":"1986"},{"key":"b12-jns131265","series-title":"Eur Arch Psychiatry Neurol Sci","doi-asserted-by":"publisher","first-page":"54","DOI":"10.1007\/BF00385667","article-title":"Pseudotumor cerebri: clinical and neuroradiological findings","volume":"237","author":"Wessel","year":"1987"},{"key":"b13-jns131265","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"1690","DOI":"10.1212\/01.wnl.0000242704.60275.e9","article-title":"CSF opening pressure: reference interval and the effect of body mass index","volume":"67","author":"Whiteley","year":"2006"},{"key":"b14-jns131265","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"667","DOI":"10.3171\/2013.2.PEDS12560","article-title":"Skull thickening, paranasal sinus expansion, and sella turcica shrinkage from chronic intracranial hypotension. 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