{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,21]],"date-time":"2026-02-21T21:02:04Z","timestamp":1771707724116,"version":"3.50.1"},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2014,3]]},"abstract":"<jats:p>Surgical options for pediatric patients with marked dysfunction of a single epileptogenic hemisphere have evolved over time. Complications resulting from highly resective operations such as anatomical hemispherectomy, including superficial siderosis and secondary hydrocephalus, have led to the development of less resective and more disconnective functional hemispherectomy. Functional hemispherectomy has recently given rise to hemispherotomy, the least resective operation primarily aimed at disconnecting the abnormal hemisphere. Hemispherotomy is effective in decreasing seizure frequency and most likely decreases the risk of postoperative complications when compared with its predecessors. Hemispherotomy is a technically challenging operation that requires a thorough understanding of 3D cerebral anatomy to ensure adequate hemispheric disconnection without placing important structures at risk. The details of germane operative anatomy are not currently available because of the difficulty in exposing this operative anatomy adequately in cadavers to prepare detailed instructive illustrations. Using 3D graphic models, the authors have prepared 2D overlay illustrations to discuss the relevant operative nuances for a modified form of this procedure. Through hemispherotomy, experienced surgeons can effectively treat patients with unilateral epileptogenic hemisphere dysfunction while limiting potential complications.<\/jats:p>","DOI":"10.3171\/2013.12.peds13277","type":"journal-article","created":{"date-parts":[[2014,1,10]],"date-time":"2014-01-10T17:06:59Z","timestamp":1389373619000},"page":"332-338","source":"Crossref","is-referenced-by-count":8,"title":["Modified periinsular hemispherotomy: operative anatomy and technical nuances"],"prefix":"10.3171","volume":"13","author":[{"given":"Timothy J.","family":"Kovanda","sequence":"first","affiliation":[{"name":"Goodman Campbell Brain and Spine, Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Roberto","family":"Rey-Dios","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jared","family":"Travnicek","sequence":"additional","affiliation":[{"name":"Goodman Campbell Brain and Spine, Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aaron A.","family":"Cohen-Gadol","sequence":"additional","affiliation":[{"name":"Goodman Campbell Brain and Spine, Department of Neurological Surgery, Indiana University School of Medicine, Indianapolis, Indiana; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-peds13277","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"945","DOI":"10.1007\/s00381-006-0145-0","article-title":"Pre-surgical evaluation and surgical treatment in children with extratemporal epilepsy","volume":"22","author":"Centeno","year":"2006"},{"issue":"2 Suppl Pediatrics","key":"b2-peds13277","series-title":"J Neurosurg","first-page":"125","article-title":"Cerebral hemispherectomy in pediatric patients with epilepsy: comparison of three techniques by pathological substrate in 115 patients","volume":"100","author":"Cook","year":"2004"},{"key":"b3-peds13277","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"952","DOI":"10.1111\/j.1528-1167.2006.00569.x","article-title":"Proposed criteria for referral and evaluation of children for epilepsy surgery: recommendations of the Subcommission for Pediatric Epilepsy Surgery","volume":"47","author":"Cross","year":"2006"},{"key":"b4-peds13277","series-title":"JAMA","doi-asserted-by":"publisher","first-page":"823","DOI":"10.1001\/jama.1928.02690380007003","article-title":"Removal of right cerebral hemisphere for certain tumors with hemiplegia","volume":"90","author":"Dandy","year":"1928"},{"issue":"3","key":"b5-peds13277","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E14","DOI":"10.3171\/FOC\/2008\/25\/9\/E14","article-title":"Hemispherotomy and other disconnective techniques","volume":"25","author":"De Ribaupierre","year":"2008"},{"issue":"2 Suppl 1","key":"b6-peds13277","series-title":"Neurosurgery","first-page":"ONS19","article-title":"Vertical parasagittal hemispherotomy: surgical procedures and clinical long-term outcomes in a population of 83 children","volume":"60","author":"Delalande","year":"2007"},{"key":"b7-peds13277","series-title":"AJR Am J Roentgenol","doi-asserted-by":"publisher","first-page":"347","DOI":"10.2214\/ajr.152.2.347","article-title":"Efficacy of MR vs CT in epilepsy","volume":"152","author":"Heinz","year":"1989"},{"key":"b8-peds13277","series-title":"Pediatr Neurosurg","doi-asserted-by":"publisher","first-page":"71","DOI":"10.1159\/000315321","article-title":"A novel method for confirmation of hemispheric disconnection during hemispherotomy surgery","volume":"46","author":"Kim","year":"2010"},{"key":"b9-peds13277","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1136\/jnnp.13.4.243","article-title":"Infantile hemiplegia treated by removing one cerebral hemisphere","volume":"13","author":"Krynauw","year":"1950"},{"key":"b10-peds13277","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"323","DOI":"10.3171\/2009.5.PEDS0942","article-title":"Hemispherotomy: efficacy and analysis of seizure recurrence. 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