{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,4,23]],"date-time":"2026-04-23T06:45:44Z","timestamp":1776926744249,"version":"3.51.2"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2013,6]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Intrasacral meningoceles are rare cystic lesions that can cause focal compression within the bony sacral canal. Their mechanisms are poorly understood, but most intrasacral meningoceles appear to be intrasacral extradural cysts caused by arachnoid herniating through a small dural defect in the caudal end of the thecal sac. As opposed to perineural cysts, they are not associated with an exiting nerve root. When symptomatic, they can cause sacral pain or sacral nerve root dysfunction due to local compression.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>This is a retrospective series from Boston Children's Hospital. All patients in whom symptomatic intrasacral meningocele that required surgical treatment was diagnosed between May 1994 and March 2011 were included in the study. Spine MRI was the diagnostic modality of choice. All patients underwent sacral exploration, with ligation and obliteration of the cyst. Resected cyst wall was subjected to pathological examination.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>There were 13 patients (11 boys and 2 girls) who underwent operation for intrasacral meningocele. The median age was 8 years (range 5 months\u201316 years). The most common presenting symptom was back pain (in 5) often described as deep tail bone pain, followed by urinary incontinence (3) and constipation (2). Three patients had evidence of associated tethered cord on MRI studies. Four patients were asymptomatic and their diagnosis was made following imaging for other reasons; they were surgically treated because of the increasing size of the lesion or association with other congenital lesions. Most patients had symptomatic improvement after surgery.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Intrasacral meningoceles are rare lesions that may result from a congenital dural weakness and a resultant arachnoid diverticulum. They present in childhood either incidentally or with symptoms secondary to nerve root compression. Identification of the point of herniation through the dura mater and ligation of the lesion provides cyst cure and resolution of symptoms in most patients.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2013.3.peds12519","type":"journal-article","created":{"date-parts":[[2013,4,19]],"date-time":"2013-04-19T14:00:01Z","timestamp":1366380001000},"page":"615-622","source":"Crossref","is-referenced-by-count":18,"title":["Intrasacral meningocele in the pediatric population"],"prefix":"10.3171","volume":"11","author":[{"given":"Subash","family":"Lohani","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Diana P.","family":"Rodriguez","sequence":"additional","affiliation":[{"name":"Neuroradiology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hart G. W.","family":"Lidov","sequence":"additional","affiliation":[{"name":"Neuropathology, Boston Children's Hospital, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"R. Michael","family":"Scott","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark R.","family":"Proctor","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-peds12519","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"67","DOI":"10.1007\/BF01407669","article-title":"Management problems in cases with a combination of asymptomatic occult intrasacral meningocele and disc prolapse","volume":"108","author":"Bayar","year":"1991"},{"key":"b2-peds12519","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"432","DOI":"10.3171\/2012.1.PEDS11391","article-title":"Spinal arachnoid cysts in the pediatric population: report of 31 cases and a review of the literature. 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A case report","volume":"62","author":"Fardon","year":"1980"},{"key":"b6-peds12519","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"281","DOI":"10.3171\/SPI\/2008\/9\/9\/281","article-title":"Giant sacral meningeal diverticulum containing a thickened filum with lipoma in an adult with spinal cord tethering. Case report and review of the literature","volume":"9","author":"Feigenbaum","year":"2008"},{"key":"b7-peds12519","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"658","DOI":"10.1136\/jnnp.2003.021709","article-title":"Intracranial hypotension caused by traumatic intrasacral meningocele","volume":"75","author":"Kihara","year":"2004"},{"issue":"1 Suppl","key":"b8-peds12519","series-title":"J Neurosurg","first-page":"108","article-title":"Expanding occult intrasacral meningocele associated with diastematomyelia and multiple vertebral anomalies. Case report","volume":"101","author":"Kili\u00e7kesmez","year":"2004"},{"key":"b9-peds12519","series-title":"Neurol India","first-page":"279","article-title":"Gluteal neuralgia\u2014unusual presentation in an adult with intrasacral meningocele: a case report and review of literature","volume":"48","author":"Mishra","year":"2000"},{"key":"b10-peds12519","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"366","DOI":"10.3171\/jns.1988.68.3.0366","article-title":"Updated assessment and current classification of spinal meningeal cysts","volume":"68","author":"Nabors","year":"1988"},{"key":"b11-peds12519","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"65","DOI":"10.1007\/s00381-003-0828-8","article-title":"A case of occult intrasacral meningocele presented with atypical bowel symptoms","volume":"20","author":"Nishio","year":"2004"},{"key":"b12-peds12519","series-title":"J Assoc Physicians India","first-page":"746","article-title":"Intrasacral meningocele with tethered cord syndrome","volume":"49","author":"Parmar","year":"2001"},{"key":"b13-peds12519","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1227\/00006123-198102000-00017","article-title":"Intrasacral extradural communicating arachnoid cyst: cases report","volume":"8","author":"Rengachary","year":"1981"},{"key":"b14-peds12519","series-title":"Am J Pathol","first-page":"53","article-title":"The origin of subdural neomembranes. I. Fine structure of the dura-arachnoid interface in man","volume":"92","author":"Schachenmayr","year":"1978"},{"key":"b15-peds12519","series-title":"Arch Neurol Psychiatry","doi-asserted-by":"publisher","first-page":"1067","DOI":"10.1001\/archneurpsyc.1938.02270120017001","article-title":"Perineural cysts of the spinal nerve roots","volume":"40","author":"Tarlov","year":"1938"},{"key":"b16-peds12519","series-title":"Neurosurg Rev","doi-asserted-by":"publisher","first-page":"313","DOI":"10.1007\/BF00306825","article-title":"Management of occult intrasacral meningocele associated with lumbar disc prolapse","volume":"17","author":"Tatagiba","year":"1994"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/11\/6\/article-p615.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/11\/6\/article-p615.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/11\/6\/article-p615.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T14:27:37Z","timestamp":1681568857000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/11\/6\/article-p615.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2013,6]]},"references-count":16,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/2013.3.peds12519","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2013,6]]}}}