{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T00:59:21Z","timestamp":1791421161817,"version":"4.3.3"},"reference-count":46,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2013,9]]},"abstract":"<jats:p>The authors present the case of a 20-year-old man who, 3 months after his initial injury, underwent repair of a 1.7-cm defect of the ulnar nerve at the wrist; repair was performed with an acellular nerve allograft. Given the absence of clinical or electrophysiological recovery at 8 months postrepair, the patient underwent reexploration, excision of the \u201cregenerated cable,\u201d and rerepair of the ulnar nerve with sural nerve autografts. Histology of the cable demonstrated minimal axonal regeneration at the midpoint of the repair. At the 6- and 12-month follow-ups of the sural nerve graft repair, clinical and electrophysiological evidence of both sensory and motor reinnervation of the ulnar nerve and associated hand muscles was demonstrated. In this report, the authors describe a single case of failed acellular nerve allograft and correlate the results with basic science and human studies reporting length and diameter limitations in human nerve repair utilizing grafts or conduits devoid of viable Schwann cells.<\/jats:p>","DOI":"10.3171\/2013.4.jns121938","type":"journal-article","created":{"date-parts":[[2013,6,7]],"date-time":"2013-06-07T13:58:02Z","timestamp":1370613482000},"page":"733-738","source":"Crossref","is-referenced-by-count":34,"title":["Limitations of nerve repair of segmental defects using acellular conduits"],"prefix":"10.3171","volume":"119","author":[{"given":"Yerko A.","family":"Berrocal","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Vania W.","family":"Almeida","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Allan D.","family":"Levi","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns121938","series-title":"Indian J Neurotrauma","doi-asserted-by":"publisher","first-page":"15","DOI":"10.1016\/S0973-0508(08)80023-8","article-title":"Entubulation techniques in peripheral nerve repair","volume":"5","author":"Babu","year":"2008"},{"key":"b2-jns121938","series-title":"Microsurgery","doi-asserted-by":"publisher","first-page":"258","DOI":"10.1002\/micr.20127","article-title":"Nerve repair by means of tubulization: literature review and personal clinical experience comparing biological and synthetic conduits for sensory nerve repair","volume":"25","author":"Battiston","year":"2005"},{"key":"b3-jns121938","series-title":"Neurol Res","doi-asserted-by":"publisher","first-page":"151","DOI":"10.1179\/016164104225013798","article-title":"Peripheral nerve regeneration through guidance tubes","volume":"26","author":"Belkas","year":"2004"},{"key":"b4-jns121938","series-title":"J Neurosurg","article-title":"Transplantation of Schwann cells in a collagen tube for the repair of large, segmental peripheral nerve defects in rats. 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