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The mass was resected in gross-total fashion, and pathological analysis revealed an SCC. Postoperatively, the patient regained full strength in his lower extremities. After the resection, he received radiotherapy administered at an isodose of 50 Gy. To the authors' knowledge, this is the first reported case of malignant transformation of an intramedullary spinal EC in the literature.<\/jats:p>","DOI":"10.3171\/2013.8.spine13150","type":"journal-article","created":{"date-parts":[[2013,9,20]],"date-time":"2013-09-20T13:59:57Z","timestamp":1379685597000},"page":"591-594","source":"Crossref","is-referenced-by-count":8,"title":["Malignant transformation of an intramedullary epidermoid cyst in the thoracic region of the spinal cord"],"prefix":"10.3171","volume":"19","author":[{"given":"Aravind","family":"Somasundaram","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Glenn J.","family":"Lesser","sequence":"additional","affiliation":[{"name":"Hematology and Oncology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Ryan T.","family":"Mott","sequence":"additional","affiliation":[{"name":"Pathology, Wake Forest Baptist Medical Center, Winston-Salem, North Carolina"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Wesley","family":"Hsu","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-spine13150","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"574","DOI":"10.1227\/00006123-198904000-00014","article-title":"Multiple complications from an intracranial epidermoid cyst: case report and literature review","volume":"24","author":"Abramson","year":"1989"},{"key":"b2-spine13150","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1054\/jocn.2000.0856","article-title":"Malignant transformation of cerebello-pontine angle epidermoid","volume":"8","author":"Asahi","year":"2001"},{"key":"b3-spine13150","series-title":"Clin Neurol Neurosurg","doi-asserted-by":"publisher","first-page":"841","DOI":"10.1016\/j.clineuro.2012.08.002","article-title":"Intramedullary thoracic spine epidermoid cyst with myelopathic presentations: a report of a rare case","volume":"115","author":"Fereydoonian","year":"2013"},{"key":"b4-spine13150","series-title":"Spinal Cord","doi-asserted-by":"publisher","first-page":"645","DOI":"10.1038\/sj.sc.3101482","article-title":"Intramedullary epidermoid cyst presenting with abnormal urological manifestations","volume":"41","author":"Ferrara","year":"2003"},{"key":"b5-spine13150","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"276","DOI":"10.1136\/jnnp.28.3.276","article-title":"Squamous cell carcinoma developing in an intracranial epidermoid cyst (cholesteatoma)","volume":"28","author":"Fox","year":"1965"},{"key":"b6-spine13150","series-title":"Neurol Med Chir (Tokyo)","doi-asserted-by":"publisher","first-page":"442","DOI":"10.2176\/nmc.49.442","article-title":"Recurrent epidermoid cyst with malignant transformation into squamous cell carcinoma","volume":"49","author":"Ge","year":"2009"},{"key":"b7-spine13150","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"618","DOI":"10.3171\/jns.1987.66.4.0618","article-title":"Squamous cell carcinoma as a late complication of intracerebroventricular epidermoid cyst. 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