{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,21]],"date-time":"2026-08-21T12:05:41Z","timestamp":1787313941783,"version":"build-2736575974"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2015,6]]},"abstract":"\n OBJECT<\/jats:title>\n The goal of this study was to determine the value of the 3D sampling perfection with application-optimized contrasts using different flip-angle evolutions (3D-SPACE) technique in the evaluation of endoscopic third ventriculostomy (ETV) patency.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n Twenty-six patients with ETV were examined using 3-T MRI units. Sagittal-plane 3D-SPACE with variant flip-angle mode, 3D T1-weighted (T1W), and 3D heavily T2-weighted (T2W) images were obtained with isotropic voxel sizes. Also, sagittal-axial plane phase-contrast cine (PC)-MR images were obtained. The following findings were evaluated: diameters of stoma and third ventricle, flow-void sign on 3D-SPACE and PC-MR images, integrity of the third ventricle on heavily T2W images, and quantitative PC-MRI parameters of the stoma. Obtained sequences were evaluated singly, in combination with one another, and all together.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n The mean area, flow, and velocity values measured at the level of stoma in patients with patent stoma were significantly higher than those measured in patients with closed stoma (p < 0.05). There was significant correlation among PC-MRI, 3D-SPACE, and 3D heavily T2W techniques regarding assessment of ETV patency (p < 0.001). The 3D-SPACE technique provided the lowest rate of ambiguous results.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n The 3D-SPACE technique seems to be the most efficient one for determination of ETV patency. The authors suggest the use of 3D-SPACE as a stand-alone first-line sequence in addition to routine brain MRI protocols in assessing patients with ETV, thereby decreasing scan time and reserving the use of a combination of additional sequences such as PC-MRI and 3D heavily T2W images in suspicious or complex cases.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2014.10.jns14298","type":"journal-article","created":{"date-parts":[[2015,4,10]],"date-time":"2015-04-10T20:27:01Z","timestamp":1428697621000},"page":"1347-1355","source":"Crossref","is-referenced-by-count":27,"title":["Assessment of third ventriculostomy patency with the 3D-SPACE technique: a preliminary multicenter research study"],"prefix":"10.3171","volume":"122","author":[{"given":"Oktay","family":"Algin","sequence":"first","affiliation":[{"name":"Department of Radiology, Ataturk Training and Research Hospital;"},{"name":"Bilkent University, National MR Research Center (UMRAM), Bilkent, Ankara;\u00a0"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Murat","family":"Ucar","sequence":"additional","affiliation":[{"name":"Departments of Radiology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Evrim","family":"Ozmen","sequence":"additional","affiliation":[{"name":"Department of Radiology, Ataturk Training and Research Hospital;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alp Ozgun","family":"Borcek","sequence":"additional","affiliation":[{"name":"Neurosurgery, Gazi University Medical Faculty;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pinar","family":"Ozisik","sequence":"additional","affiliation":[{"name":"Neurosurgery Clinic, Koru Hospital, Ankara; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gokhan","family":"Ocakoglu","sequence":"additional","affiliation":[{"name":"Biostatistics, Uludag University, Gorukle, Bursa, Turkey"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"E. 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