{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,14]],"date-time":"2025-11-14T07:30:26Z","timestamp":1763105426587},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2015,8]]},"abstract":"<jats:p>A 13-year-old boy presented with fever and neck pain and stiffness, which was initially misdiagnosed as culture-negative meningitis. Magnetic resonance images of the brain and cervical spine demonstrated what appeared to be an intradural extramedullary mass at the C1\u20133 level, resulting in moderate cord compression, and a Chiari Type I malformation. The patient underwent a suboccipital craniectomy and a C1\u20133 laminectomy with intradural exploration for excisional biopsy and resection. The lesion containing the parasite was extradural, extending laterally through the C2\u20133 foramina. Inflammatory tissue secondary to <jats:italic>Onchocerca lupi<\/jats:italic> infection was identified, and treatment with steroids and doxycycline was initiated. At the 6-month follow-up, the patient remained asymptomatic, with MR images demonstrating a significant reduction in lesional size. However, 10 weeks postoperatively, the infection recurred, necessitating a second operation. The patient was treated with an additional course of doxycycline and is currently maintained on ivermectin therapy. This is the second reported case of cervical <jats:italic>O. lupi<\/jats:italic> infection in a human. In the authors' experience, oral doxycycline alone was insufficient in controlling the disease, and the addition of ivermectin therapy was necessary.<\/jats:p>","DOI":"10.3171\/2014.12.peds14462","type":"journal-article","created":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T13:59:08Z","timestamp":1430488748000},"page":"217-221","source":"Crossref","is-referenced-by-count":22,"title":["Case report of an epidural cervical Onchocerca lupi infection in a 13-year-old boy"],"prefix":"10.3171","volume":"16","author":[{"given":"Tsinsue","family":"Chen","sequence":"first","affiliation":[{"name":"Department of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Karam","family":"Moon","sequence":"additional","affiliation":[{"name":"Department of Neurological Surgery, Barrow Neurological Institute, St. Joseph's Hospital and Medical Center;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daphne E.","family":"deMello","sequence":"additional","affiliation":[{"name":"Department of Pathology and Laboratory Medicine, Phoenix Children's Hospital;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Iman","family":"Feiz-Erfan","sequence":"additional","affiliation":[{"name":"The University of Arizona, College of Medicine\u2013Phoenix; 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