{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,14]],"date-time":"2026-02-14T11:34:31Z","timestamp":1771068871891,"version":"3.50.1"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2014,7]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>The benefits of treating intracranial aneurysms in the region of the anterior visual pathways are well understood. However, the adverse effects of endovascular stenting across the ophthalmic artery have received little attention. The authors reviewed their experience with patients who had stents deployed across the ophthalmic artery origin.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>Patients' medical charts and imaging studies were reviewed to identify all patients with a non\u2013flow diverting stent deployed over the ophthalmic artery origin for the treatment of intracranial aneurysms. All patients with neuro-ophthalmic complaints were referred for formal ophthalmological evaluation.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>A total of 104 consecutive patients with 106 aneurysms were identified to meet criteria for inclusion in the study cohort. Preoperatively, 30 patients (29%) described headache symptoms and 32 patients (31%) reported visual complaints. Of the patients with preoperative headaches, 15 (54%) of 28 patients for whom follow-up was available experienced improvement in their symptoms. Of the patients with preoperative visual complaints, improvement was noted in 11 (41%) of the 27 patients for whom follow-up was available, 9 (33%) of 27 patients reported no change in visual symptoms, and 7 (26%) of 27 patients reported progression of symptoms. Visual field defects developing posttreatment were noted to occur in 8 (7.7%) of 104 patients: 3 with immediate postoperative retinal infarcts, 1 with perioperative hemianopia that resolved by the time of discharge, 1 with a subjective visual field defect, 1 with subjective migratory visual field defects, and 2 with nonspecific visual symptoms. Compressive symptoms from aneurysm mass effect were noted in 6 patients preoperatively, with 4 of those patients experiencing persistent worsening, resolution in 1 case, and no change in 1 case. One patient developed a novel cranial nerve palsy from mass effect in the immediate postoperative period.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Deployment of stents across the ophthalmic artery origin for the treatment of intracranial aneurysms appears to be relatively safe with regard to visual outcomes. Neuro-ophthalmic complaint resolution rates were comparable to endovascular procedures that do not employ stents, with headache resolution rates comparable to coil-only aneurysm obliteration and low rates of retinal ischemic events. For patients presenting with mass effect, stent-assisted coiling appears to be less effective than microsurgery with decompression for relief of compressive symptoms.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2014.3.jns131493","type":"journal-article","created":{"date-parts":[[2014,4,11]],"date-time":"2014-04-11T14:00:41Z","timestamp":1397224841000},"page":"18-23","source":"Crossref","is-referenced-by-count":13,"title":["Neuro-ophthalmic effects of stenting across the ophthalmic artery origin in the treatment of intracranial aneurysms"],"prefix":"10.3171","volume":"121","author":[{"given":"Robert S.","family":"Heller","sequence":"first","affiliation":[{"name":"Cerebrovascular and Endovascular Division, Department of Neurosurgery; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Claire M.","family":"Lawlor","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology and Neurology, New England Eye Center, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Thomas R.","family":"Hedges","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology and Neurology, New England Eye Center, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yanik J.","family":"Bababekov","sequence":"additional","affiliation":[{"name":"Departments of Ophthalmology and Neurology, New England Eye Center, Tufts Medical Center and Tufts University School of Medicine, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mina G.","family":"Safain","sequence":"additional","affiliation":[{"name":"Cerebrovascular and Endovascular Division, Department of Neurosurgery; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Adel M.","family":"Malek","sequence":"additional","affiliation":[{"name":"Cerebrovascular and Endovascular Division, Department of Neurosurgery; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-jns131493","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"128","DOI":"10.1227\/NEU.0b013e318213437d","article-title":"Both surgical clipping and endovascular embolization of unruptured intracranial aneurysms are associated with long-term improvement in self-reported quantitative headache scores","volume":"69","author":"Choxi","year":"2011"},{"key":"b2-jns131493","series-title":"Clin Neurol Neurosurg","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1016\/S0303-8467(98)00047-X","article-title":"Cerebral aneurysms causing visual symptoms: their features and surgical outcome","volume":"100","author":"Date","year":"1998"},{"issue":"5","key":"b3-jns131493","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E3","DOI":"10.3171\/2009.3.FOCUS0924","article-title":"Intracranial aneurysms presenting with mass effect over the anterior optic pathways: neurosurgical management and outcomes","volume":"26","author":"de Oliveira","year":"2009"},{"key":"b4-jns131493","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/S0090-3019(81)80049-3","article-title":"Carotid-ophthalmic aneurysms: visual abnormalities in 32 patients and the results of treatment","volume":"16","author":"Ferguson","year":"1981"},{"key":"b5-jns131493","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"218","DOI":"10.1227\/01.NEU.0000337127.73667.80","article-title":"Results, outcomes, and follow-up of remnants in the treatment of ophthalmic aneurysms: a 16-year experience of a combined neurosurgical and endovascular team","volume":"64","author":"Fulkerson","year":"2009"},{"key":"b6-jns131493","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"968","DOI":"10.3171\/jns.2007.106.6.968","article-title":"Large ophthalmic segment aneurysms with anterior optic pathway compression: assessment of anatomical and visual outcomes after endosaccular coil therapy","volume":"106","author":"Heran","year":"2007"},{"key":"b7-jns131493","series-title":"Neurosurgery","first-page":"78","article-title":"Results after surgical and endovascular treatment of paraclinoid aneurysms by a combined neurovascular team","volume":"48","author":"Hoh","year":"2001"},{"key":"b8-jns131493","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"13","DOI":"10.1016\/j.jocn.2010.06.020","article-title":"Paraclinoid carotid aneurysms","volume":"18","author":"Javalkar","year":"2011"},{"key":"b9-jns131493","series-title":"J Neuroophthalmol","doi-asserted-by":"publisher","first-page":"27","DOI":"10.1097\/WNO.0b013e31823b6c60","article-title":"Visual sequelae after consensus-based treatment of ophthalmic artery segment aneurysms: the Johns Hopkins experience","volume":"32","author":"Kanagalingam","year":"2012"},{"key":"b10-jns131493","series-title":"Headache","doi-asserted-by":"publisher","first-page":"693","DOI":"10.1111\/j.1526-4610.2006.00630.x","article-title":"Improvement of chronic headache after treatment of unruptured intracranial aneurysms","volume":"47","author":"Kong","year":"2007"},{"key":"b11-jns131493","series-title":"Optometry","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1016\/j.optm.2008.05.009","article-title":"Enlargement of internal carotid artery aneurysm presenting with severe visual sequela: a case report and anatomy review","volume":"80","author":"Mendez Roberts","year":"2009"},{"key":"b12-jns131493","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"355","DOI":"10.1227\/NEU.0b013e3182039819","article-title":"Microneurosurgical management of ophthalmic segment of the internal carotid artery aneurysms: single-surgeon operative experience from Louisiana State University, Shreveport","volume":"68","author":"Nanda","year":"2011"},{"key":"b13-jns131493","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"14","DOI":"10.1227\/01.NEU.0000068789.08955.1C","article-title":"Endovascular treatment of paraclinoid aneurysms: experience with 73 patients","volume":"53","author":"Park","year":"2003"},{"key":"b14-jns131493","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"892","DOI":"10.3171\/2011.11.JNS111612","article-title":"Patency of the ophthalmic artery after flow diversion treatment of paraclinoid aneurysms. Clinical article","volume":"116","author":"Puffer","year":"2012"},{"key":"b15-jns131493","series-title":"Headache","doi-asserted-by":"publisher","first-page":"1090","DOI":"10.1046\/j.1526-4610.2003.03211.x","article-title":"Effect of endovascular treatment on headaches in patients with unruptured intracranial aneurysms","volume":"43","author":"Qureshi","year":"2003"},{"key":"b16-jns131493","series-title":"AJNR Am J Neuroradiol","first-page":"1207","article-title":"Endovascular treatment of ophthalmic segment aneurysms with Guglielmi detachable coils","volume":"18","author":"Roy","year":"1997"},{"key":"b17-jns131493","series-title":"AJNR Am J Neuroradiol","doi-asserted-by":"publisher","first-page":"1882","DOI":"10.3174\/ajnr.A0690","article-title":"Isolated progressive visual loss after coiling of paraclinoid aneurysms","volume":"28","author":"Schmidt","year":"2007"},{"key":"b18-jns131493","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"694","DOI":"10.3171\/2011.5.JNS101983","article-title":"Influence of surgical or endovascular treatment on visual symptoms caused by intracranial aneurysms: single-center series and systematic review. Clinical article","volume":"115","author":"Schuss","year":"2011"},{"key":"b19-jns131493","series-title":"Cephalalgia","doi-asserted-by":"publisher","first-page":"1082","DOI":"10.1177\/0333102411398155","article-title":"Headache outcomes following treatment of unruptured intracranial aneurysms: a prospective analysis","volume":"31","author":"Schwedt","year":"2011"},{"key":"b20-jns131493","series-title":"Neurol Med Chir (Tokyo)","doi-asserted-by":"publisher","first-page":"416","DOI":"10.2176\/nmc.44.416","article-title":"Cortical blindness during coil embolization of an unruptured intracranial aneurysm\u2014case report","volume":"44","author":"Shinoda","year":"2004"},{"key":"b21-jns131493","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"E1217","DOI":"10.1227\/01.NEU.0000215995.09860.0A","article-title":"Surgical decompression and coil removal for the recovery of vision after coiling and proximal occlusion of a clinoidal segment aneurysm: technical case report","volume":"58","author":"Tawk","year":"2006"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/121\/1\/article-p18.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/121\/1\/article-p18.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/121\/1\/article-p18.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,25]],"date-time":"2022-07-25T01:01:37Z","timestamp":1658710897000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/121\/1\/article-p18.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2014,7]]},"references-count":21,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/2014.3.jns131493","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,7]]}}}