{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,28]],"date-time":"2026-03-28T02:39:14Z","timestamp":1774665554521,"version":"3.50.1"},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2014,6]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Traumatic aneurysms occur in 10% of extracranial blunt traumatic cerebrovascular injuries (TCVI). The clinical consequences and optimal management of traumatic aneurysms are poorly understood.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>A prospective study of TCVI at a Level I trauma center identified 7 patients with 19 extracranial traumatic carotid artery or vertebral artery aneurysms. An additional 6 patients with 7 traumatic aneurysms were followed outside of the prospective study, giving a total of 13 patients with 26 traumatic aneurysms. All patients were treated with 325 mg aspirin daily and underwent clinical and imaging follow-up beyond the initial hospitalization. Endovascular treatment was reserved for aneurysms demonstrating significant enlargement on follow-up imaging. Clinical and radiographic features were assessed.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The 7 patients with traumatic aneurysms identified in the prospective cohort comprised 10.3% of all patients with TCVI. Two (15.4%) of the 13 total patients suffered an ischemic stroke in the setting of TCVI with traumatic aneurysm formation. No patient experienced an ischemic stroke or new symptoms after the initiation of antiplatelet therapy. Clinical and radiographic follow-up averaged 15.8 months (range 0.4\u201341.7 months) and 22.0 months (range 6.6\u201355.7 months), respectively. Ten (38.5%) of 26 aneurysms were not visualized on last follow-up, 10 (38.5%) were smaller, 1 (3.8%) was unchanged, and 5 (19.2%) were larger. Saccular aneurysms were more likely to enlarge than fusiform aneurysms (33.3% vs 11.8%). Results of a Fisher exact test tend to support the assertion that the 2 different aneurysm morphologies behave differently (p = 0.07). Two saccular aneurysms were treated with stenting.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>The majority of traumatic aneurysms can be managed with an antiplatelet regimen of 325 mg aspirin daily and serial imaging. Saccular aneurysms have a greater tendency to enlarge when compared with fusiform aneurysms.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2014.3.jns131959","type":"journal-article","created":{"date-parts":[[2014,4,4]],"date-time":"2014-04-04T14:04:08Z","timestamp":1396620248000},"page":"1437-1445","source":"Crossref","is-referenced-by-count":29,"title":["Extracranial traumatic aneurysms due to blunt cerebrovascular injury"],"prefix":"10.3171","volume":"120","author":[{"given":"Paul M.","family":"Foreman","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christoph J.","family":"Griessenauer","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Falola","sequence":"additional","affiliation":[{"name":"Department of Biostatistics, University of Alabama, Birmingham, Alabama"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark R.","family":"Harrigan","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-jns131959","series-title":"J Trauma","doi-asserted-by":"publisher","first-page":"624","DOI":"10.1097\/01.TA.0000096662.79685.EA","article-title":"Urgent endovascular stent-graft placement for a ruptured traumatic pseudoaneurysm of the extracranial carotid artery","volume":"58","author":"Akiyama","year":"2005"},{"key":"b2-jns131959","series-title":"J Trauma","doi-asserted-by":"publisher","first-page":"845","DOI":"10.1097\/00005373-199911000-00004","article-title":"Blunt carotid arterial injuries: implications of a new grading scale","volume":"47","author":"Biffl","year":"1999"},{"key":"b3-jns131959","series-title":"Ann Surg","doi-asserted-by":"publisher","first-page":"699","DOI":"10.1097\/00000658-200205000-00012","article-title":"Treatment-related outcomes from blunt cerebrovascular injuries: importance of routine follow-up arteriography","volume":"235","author":"Biffl","year":"2002"},{"key":"b4-jns131959","series-title":"J Trauma","doi-asserted-by":"publisher","first-page":"850","DOI":"10.1097\/00005373-200211000-00008","article-title":"Noninvasive diagnosis of blunt cerebrovascular injuries: a preliminary report","volume":"53","author":"Biffl","year":"2002"},{"key":"b5-jns131959","series-title":"J Trauma Acute Care Surg","doi-asserted-by":"publisher","first-page":"330","DOI":"10.1097\/TA.0b013e31823de8a0","article-title":"Blunt cerebrovascular injuries: redefining screening criteria in the era of noninvasive diagnosis","volume":"72","author":"Burlew","year":"2012"},{"key":"b6-jns131959","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"993","DOI":"10.1056\/NEJMoa1105335","article-title":"Stenting versus aggressive medical therapy for intracranial arterial stenosis","volume":"365","author":"Chimowitz","year":"2011"},{"key":"b7-jns131959","series-title":"J Trauma","first-page":"1561","article-title":"Endovascular stenting for the treatment of traumatic internal carotid injuries: expanding experience","volume":"65","author":"DuBose","year":"2008"},{"key":"b8-jns131959","series-title":"J Trauma","doi-asserted-by":"publisher","first-page":"925","DOI":"10.1097\/01.ta.0000197479.28714.62","article-title":"Computed tomographic angiography for the diagnosis of blunt cervical vascular injury: is it ready for primetime?","volume":"60","author":"Eastman","year":"2006"},{"key":"b9-jns131959","series-title":"J Am Coll Surg","doi-asserted-by":"publisher","first-page":"1007","DOI":"10.1016\/j.jamcollsurg.2006.12.041","article-title":"Antithrombotic therapy and endovascular stents are effective treatment for blunt carotid injuries: results from longterm followup","volume":"204","author":"Edwards","year":"2007"},{"key":"b10-jns131959","series-title":"J Vasc Surg","doi-asserted-by":"publisher","first-page":"702","DOI":"10.1067\/mva.2000.104101","article-title":"Extracranial carotid artery aneurysms: Texas Heart Institute experience","volume":"31","author":"El-Sabrout","year":"2000"},{"key":"b11-jns131959","series-title":"J Trauma","first-page":"1058","article-title":"Improving the screening criteria for blunt cerebrovascular injury: the appropriate role for computed tomography angiography","volume":"70","author":"Emmett","year":"2011"},{"key":"b12-jns131959","series-title":"Ann Surg","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1097\/00000658-199605000-00007","article-title":"Blunt carotid injury. Importance of early diagnosis and anticoagulant therapy","volume":"223","author":"Fabian","year":"1996"},{"key":"b13-jns131959","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1227\/NEU.0b013e3181fe2fda","article-title":"Cerebrovascular dissections: a review. Part II: blunt cerebrovascular injury","volume":"68","author":"Fusco","year":"2011"},{"key":"b14-jns131959","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"397","DOI":"10.3171\/2012.11.JNS121038","article-title":"Timing and mechanism of ischemic stroke due to extracranial blunt traumatic cerebrovascular injury. Clinical article","volume":"118","author":"Griessenauer","year":"2013"},{"issue":"Suppl 2","key":"b15-jns131959","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"234","DOI":"10.1227\/NEU.0b013e31827765f5","article-title":"Management of vertebral artery injuries following non-penetrating cervical trauma","volume":"72","author":"Harrigan","year":"2013"},{"key":"b16-jns131959","series-title":"AJNR Am J Neuroradiol","doi-asserted-by":"publisher","first-page":"91","DOI":"10.3174\/ajnr.A1768","article-title":"Sixty-four-section multidetector CT angiography of carotid arteries: a systematic analysis of image quality and artifacts","volume":"31","author":"Kim","year":"2010"},{"key":"b17-jns131959","series-title":"Ann Surg","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1097\/SLA.0b013e3181568cab","article-title":"Computed tomographic angiography for the diagnosis of blunt carotid\/vertebral artery injury: a note of caution","volume":"246","author":"Malhotra","year":"2007"},{"key":"b18-jns131959","series-title":"J Trauma","doi-asserted-by":"publisher","first-page":"279","DOI":"10.1097\/00005373-200108000-00009","article-title":"Blunt cerebrovascular injuries: diagnosis and treatment","volume":"51","author":"Miller","year":"2001"},{"key":"b19-jns131959","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"856","DOI":"10.1227\/NEU.0b013e318209ce03","article-title":"Endovascular stenting of extracranial carotid and vertebral artery dissections: a systematic review of the literature","volume":"68","author":"Pham","year":"2011"},{"key":"b20-jns131959","series-title":"J Trauma","doi-asserted-by":"publisher","first-page":"1012","DOI":"10.1097\/00005373-199511000-00036","article-title":"Blunt carotid artery injury: devastating consequences of undetected pseudoaneurysm","volume":"39","author":"Pr\u00eatre","year":"1995"},{"key":"b21-jns131959","series-title":"Arch Ophthalmol","doi-asserted-by":"publisher","first-page":"327","DOI":"10.1001\/archopht.1990.01070050025010","article-title":"Cervical spine dislocation presenting as an isolated Horner's syndrome","volume":"108","author":"Safran","year":"1990"},{"key":"b22-jns131959","series-title":"J Trauma","first-page":"132","article-title":"Blunt cerebrovascular injuries: does treatment always matter?","volume":"66","author":"Stein","year":"2009"},{"key":"b23-jns131959","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"418","DOI":"10.1161\/01.STR.32.2.418","article-title":"Aneurysmal forms of cervical artery dissection: associated factors and outcome","volume":"32","author":"Touz\u00e9","year":"2001"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/120\/6\/article-p1437.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/120\/6\/article-p1437.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/120\/6\/article-p1437.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2022,7,24]],"date-time":"2022-07-24T14:29:52Z","timestamp":1658672992000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/120\/6\/article-p1437.xml"}},"subtitle":["Clinical article"],"short-title":[],"issued":{"date-parts":[[2014,6]]},"references-count":23,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/2014.3.jns131959","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,6]]}}}