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This case is the first reported HH with pathological demonstration of corticotropin-releasing hormone immunostaining in the solid tumor and glial cells in the cyst wall of the lesion. The clinical and radiological characteristics of HHs are reviewed, along with the unique surgical strategies used to manage cystic lesions in the suprasellar region.<\/jats:p>","DOI":"10.3171\/2014.4.peds13371","type":"journal-article","created":{"date-parts":[[2014,5,16]],"date-time":"2014-05-16T14:02:44Z","timestamp":1400248964000},"page":"101-107","source":"Crossref","is-referenced-by-count":2,"title":["Hypothalamic hamartoma simulating a suprasellar arachnoid cyst: resolution of precocious puberty following microsurgical lesion resection"],"prefix":"10.3171","volume":"14","author":[{"given":"Sunil","family":"Manjila","sequence":"first","affiliation":[{"name":"Division of Pediatric Neurosurgery, Rainbow Babies and Children's Hospital, Department of Neurological Surgery, Neurological Institute;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Timothy W.","family":"Vogel","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Rainbow Babies and Children's Hospital, Department of Neurological Surgery, Neurological Institute;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yunwei","family":"Chen","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Rainbow Babies and Children's Hospital, Department of Neurological Surgery, Neurological Institute;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mark S.","family":"Rodgers","sequence":"additional","affiliation":[{"name":"Department of Pathology, University Hospitals Case Medical Center, Cleveland, Ohio; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alan R.","family":"Cohen","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Boston Children's Hospital, Harvard Medical School, Boston, Massachusetts"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"issue":"3","key":"b1-peds13371","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E8","DOI":"10.3171\/FOC\/2008\/25\/9\/E8","article-title":"Surgical management of hypothalamic hamartomas in patients with gelastic epilepsy","volume":"25","author":"Addas","year":"2008"},{"key":"b2-peds13371","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"77","DOI":"10.3171\/jns.1993.78.1.0077","article-title":"Neurosurgical treatment of hypothalamic hamartomas causing precocious puberty","volume":"78","author":"Albright","year":"1993"},{"key":"b3-peds13371","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"513","DOI":"10.1007\/s00381-013-2022-y","article-title":"Giant hypothalamic hamartoma: case report and literature review","volume":"29","author":"Alves","year":"2013"},{"key":"b4-peds13371","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"212","DOI":"10.3171\/jns.1999.91.2.0212","article-title":"The relationship between magnetic resonance imaging findings and clinical manifestations of hypothalamic hamartoma","volume":"91","author":"Arita","year":"1999"},{"issue":"Suppl","key":"b5-peds13371","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"53","DOI":"10.3171\/sup.2005.102.s_supplement.0053","article-title":"Gamma knife surgery for hypothalamic hamartomas accompanied by medically intractable epilepsy and precocious puberty: experience in Mexico","volume":"102","author":"Barajas","year":"2005"},{"key":"b6-peds13371","series-title":"Pediatr Radiol","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/BF00974075","article-title":"MRI of hypothalamic hamartomas in children","volume":"18","author":"Barral","year":"1988"},{"key":"b7-peds13371","series-title":"AJNR Am J Neuroradiol","first-page":"309","article-title":"Hamartomas of the tuber cinereum: CT, MR, and pathologic findings","volume":"12","author":"Boyko","year":"1991"},{"key":"b8-peds13371","series-title":"Arch Fr Pediatr","first-page":"489","article-title":"[Precocious puberty caused by a suprasellar arachnoid cyst. 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