{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,24]],"date-time":"2026-08-24T22:30:19Z","timestamp":1787610619980,"version":"build-2736575974"},"reference-count":25,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>This study aimed to investigate morphological predictors of intraprocedural rupture (IPR) during coil embolization of ruptured cerebral aneurysms.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>A retrospective analysis was conducted in 322 consecutive patients with ruptured cerebral aneurysms who were treated with coil embolization over an 8-year period from January 2005 to December 2012. The authors analyzed all available data with emphasis on morphological characteristics of the aneurysm as shown on baseline angiography in relation to IPR. Regarding aneurysm morphology, the authors classified patients according to multilobulation, presence of a daughter sac, and presence of a small basal outpouching (SBO).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>The incidence of IPR was 4.8% (16 of 332). In terms of aneurysm configuration, the presence of multilobulation (100.0% [16 of 16] in the IPR group vs 89.2% [282 of 316] in the non-IPR group, p = 0.388) and daughter sac (75.0% [12 of 16] in the IPR group vs 59.2% [187 of 316] in the non-IPR group, p = 0.208) were not significantly associated with IPR. However, SBO, found in 9% (30 of 332) of the study population, was significantly associated with IPR (56.3% [9 of 16] in the IPR group vs 6.7% [21 of 316] in the non-IPR group, OR 18.06, p &lt; 0.0001).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Based on the authors' data, the more general groups of multilobulation and daughter sac were not significantly associated with IPR, although the more specific subgroup with an SBO was. More confirmation studies on these results are required, but they point to the possibility that SBO (with its possible connection to basal rupture) is an important morphological risk factor for IPR during coiling. In addition, future comparison of coiling and clipping treatment for ruptured aneurysms associated with an SBO seems necessary.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2014.5.jns132107","type":"journal-article","created":{"date-parts":[[2014,6,27]],"date-time":"2014-06-27T13:57:49Z","timestamp":1403877469000},"page":"605-612","source":"Crossref","is-referenced-by-count":24,"title":["Morphological predictors of intraprocedural rupture during coil embolization of ruptured cerebral aneurysms: do small basal outpouchings carry higher risk?"],"prefix":"10.3171","volume":"121","author":[{"given":"Dong-Hun","family":"Kang","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Radiology, Kyungpook National University Hospital, Daeg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Duck-Ho","family":"Goh","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Kug","family":"Baik","sequence":"additional","affiliation":[{"name":"Department of Radiology, Pusan National University Yangsan Hospital, Yangsan, Republic of Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jaechan","family":"Park","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yong-Sun","family":"Kim","sequence":"additional","affiliation":[{"name":"Radiology, Kyungpook National University Hospital, Daeg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns132107","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1103","DOI":"10.1227\/01.NEU.0000185631.20246.1A","article-title":"Aneurysmal rupture during coiling: low incidence and good outcomes at a single large volume center","volume":"57","author":"Brisman","year":"2005"},{"key":"b2-jns132107","series-title":"AJNR Am J Neuroradiol","first-page":"1706","article-title":"Cerebral aneurysm perforations complicating therapy with Guglielmi detachable coils: a metaanalysis","volume":"23","author":"Cloft","year":"2002"},{"key":"b3-jns132107","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1148\/radiology.206.2.9457205","article-title":"Intracranial berry aneurysms: angiographic and clinical results after endovascular treatment","volume":"206","author":"Cognard","year":"1998"},{"key":"b4-jns132107","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"259","DOI":"10.1136\/jnnp.22.4.259","article-title":"Some observations on the pathogenesis and natural history of intracranial aneurysms","volume":"22","author":"Crawford","year":"1959"},{"key":"b5-jns132107","series-title":"Br Med J","doi-asserted-by":"publisher","first-page":"1138","DOI":"10.1136\/bmj.1.5496.1138","article-title":"Mechanism of growth and rupture in cerebral berry aneurysms","volume":"1","author":"Crompton","year":"1966"},{"key":"b6-jns132107","series-title":"AJNR Am J Neuroradiol","first-page":"1825","article-title":"Aneurysmal rupture during embolization with Guglielmi detachable coils: causes, management, and outcome","volume":"22","author":"Doerfler","year":"2001"},{"key":"b7-jns132107","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"1501","DOI":"10.1161\/STROKEAHA.107.504670","article-title":"Predictors and outcomes of intraprocedural rupture in patients treated for ruptured intracranial aneurysms: the CARAT study","volume":"39","author":"Elijovich","year":"2008"},{"key":"b8-jns132107","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"517","DOI":"10.3171\/jns.2000.93.3.0517","article-title":"Prediction of aneurysm rupture site by an angiographically identified bleb at the aneurysm neck. 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