{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,30]],"date-time":"2026-09-30T00:31:22Z","timestamp":1790728282120,"version":"4.1.0"},"reference-count":11,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2014,9]]},"abstract":"<jats:sec>\n<jats:title>Object<\/jats:title>\n<jats:p>Endoscopic choroid plexus coagulation (CPC) with or without endoscopic third ventriculostomy (ETV) has been shown to be effective for selected patients with hydrocephalus. However, whether the effect of the coagulation is temporary and the choroid plexus regenerates or can be obliterated has remained largely unknown. The authors evaluate the effectiveness of CPC and report 3 cases of obliteration demonstrated by direct endoscopic observation.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Methods<\/jats:title>\n<jats:p>The authors retrospectively analyzed the surgical results of patients with hydrocephalus primarily treated by CPC with or without ETV. Charts were reviewed for demographic data, clinical presentations, surgical therapies, and clinical outcomes.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Results<\/jats:title>\n<jats:p>Eighteen patients with hydrocephalus were surgically treated using endoscopic CPC between July 2002 and July 2012. In 12 patients, ETV was concurrently performed. The etiology of hydrocephalus was posthemorrhagic in 5 patients, myelomeningocele in 3, postmeningitis in 2, congenital aqueductal stenosis in 1, hydranencephaly in 1, porencephaly in 1, and idiopathic in 5.<\/jats:p>\n<jats:p>The mean age at surgery was 8 months (range 0.3\u201324 months). The mean follow-up was 64 months. In 9 cases (50%), control of hydrocephalus was successful and the patients did not require further surgeries. In 9 patients (50%), treatment failed. Of these, 3 patients underwent repeat ETV 2, 3, and 38 months after the initial surgery. Endoscopic observation of the previous coagulation site revealed no regeneration of the choroid plexus in 2 patients, who underwent repeat ETV 2 and 3 months after CPC. In 1 patient who underwent repeat ETV 38 months after CPC, no regeneration of the choroid plexus, except for that in the proximity of the foramen of Monro, was observed.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>Conclusions<\/jats:title>\n<jats:p>Endoscopic CPC with or without ETV can be a safe and effective treatment alternative to shunt placement in infantile hydrocephalus. Obliteration of the choroid plexus can persist in the relatively long term following CPC, which may contribute to the long-term control of hydrocephalus in successful cases.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2014.6.peds1438","type":"journal-article","created":{"date-parts":[[2014,7,4]],"date-time":"2014-07-04T13:59:32Z","timestamp":1404482372000},"page":"230-233","source":"Crossref","is-referenced-by-count":19,"title":["Obliteration of the choroid plexus after endoscopic coagulation"],"prefix":"10.3171","volume":"14","author":[{"given":"Hideki","family":"Ogiwara","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kodai","family":"Uematsu","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nobuhito","family":"Morota","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-peds1438","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1227\/00006123-199103000-00014","article-title":"Endoscopic coagulation of the choroid plexus using the Nd:YAG laser: initial experience and proposal for management","volume":"28","author":"Bucholz","year":"1991"},{"key":"b2-peds1438","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1227\/01.NEU.0000126938.12817.DC","article-title":"Endoscopic third ventriculostomy in idiopathic normal pressure hydrocephalus","volume":"55","author":"Gangemi","year":"2004"},{"key":"b3-peds1438","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"487","DOI":"10.1007\/s00381-007-0303-z","article-title":"Paradigm shift in hydrocephalus research in legacy of Dandy's pioneering work: rationale for third ventriculostomy in communicating hydrocephalus","volume":"23","author":"Greitz","year":"2007"},{"key":"b4-peds1438","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"169","DOI":"10.3171\/2011.11.PEDS11154","article-title":"Endoscopic coagulation of choroid plexus hyperplasia. 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