{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:02:25Z","timestamp":1787025745146,"version":"build-2736575974"},"reference-count":62,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2014,9]]},"abstract":"\n Object<\/jats:title>\n Sylvian arteriovenous malformations (sAVMs) are challenging lesions of the central nervous system. The natural history of these unique lesions as well as clinical outcomes following treatment of sAVMs has been limited to case series owing to the rarity of these lesions. The authors present their experience with sAVMs and review the literature.<\/jats:p>\n <\/jats:sec>\n \n Methods<\/jats:title>\n In accordance with the Henry Ford Institutional Review Board, medical records of patients with sAVMs treated from 2000 to 2012 were reviewed. Clinical data were retrospectively collected to calculate pre- and posttreatment modified Rankin Scale scores for all patients.<\/jats:p>\n <\/jats:sec>\n \n Results<\/jats:title>\n The authors identified 15 patients with sAVMs who received treatment. Of these, 12 were female and 3 were male, and the average age at presentation was 39.6 \u00b1 12.94 years (\u00b1 SD). Two patients (13.3%) had Spetzler-Martin Grade I lesions, 6 patients (40%) had Grade II lesions, 5 patients (33.3%) had Grade III lesions, and another 2 (13.3%) harbored Grade IV arteriovenous malformations (AVMs). According to the Sugita classification, 6 patients (40%) had medial lesions, 6 (40%) had lateral lesions, 2 (13.3%) had deep lesions, and 1 patient (6.67%) had a pure sAVM. Eight patients (53.3%) underwent stereotactic radiosurgery while 7 patients (46.7%) had microsurgical resection; 1 patient underwent surgical extirpation after incomplete response following radiosurgery. After treatment, 9 patients were unchanged from pretreatment (60%), 3 patients worsened, and 2 patients had improved functional outcome (20% and 13.3%, respectively). The authors\u2019 literature search yielded 348 patients with sAVMs, most of them harboring Spetzler-Martin Grade II and III lesions. Approximately 98% of the patients underwent resection with excellent outcomes.<\/jats:p>\n <\/jats:sec>\n \n Conclusions<\/jats:title>\n While the ideal choice of therapeutic modality for cerebral AVMs remains controversial in light of the recent publication of the ARUBA (A Randomized trial of Unruptured Brain AVMs) trial, a multidisciplinary treatment approach for the management of sAVMs can lead to acceptable neurological outcome.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2014.7.focus14246","type":"journal-article","created":{"date-parts":[[2014,9,1]],"date-time":"2014-09-01T03:40:04Z","timestamp":1409542804000},"page":"E13","source":"Crossref","is-referenced-by-count":6,"title":["Management of perisylvian arteriovenous malformations: a retrospective institutional case series and review of the literature"],"prefix":"10.3171","volume":"37","author":[{"given":"Aqueel H.","family":"Pabaney","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kevin A.","family":"Reinard","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lara W.","family":"Massie","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Padmaja K.","family":"Naidu","sequence":"additional","affiliation":[{"name":"Departments of Radiology, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Yedathore S.","family":"Mohan","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Horia","family":"Marin","sequence":"additional","affiliation":[{"name":"Departments of Radiology, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ghaus M.","family":"Malik","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery, Henry Ford Hospital, Detroit, Michigan"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-0370013","series-title":"Acta Neurochir (Wien)","first-page":"271","article-title":"The place for surgical treatment for AVM involving the temporal lobe","volume":"153","author":"Bostr\u00f6m","year":"2011"},{"key":"b2-0370013","series-title":"Neurosurgery","first-page":"804","article-title":"Functional magnetic resonance imaging and optical imaging for dominant-hemisphere perisylvian arteriovenous malformations","volume":"55","author":"Cannestra","year":"2004"},{"key":"b3-0370013","series-title":"J Neurosurg","first-page":"470","article-title":"Radiosurgery for ruptured intracranial arteriovenous malformations. Clinical article","volume":"121","author":"Ding","year":"2014"},{"key":"b4-0370013","series-title":"Neurosurgery","first-page":"645","article-title":"\u201cTangential\u201d resection of medial temporal lobe arteriovenous malformations with the orbitozygomatic approach","volume":"54","author":"Du","year":"2004"},{"issue":"3 Suppl Operative","key":"b5-0370013","series-title":"Neurosurgery","first-page":"ons237","article-title":"Microvascular anatomy of the medial temporal region: Part 1: its application to arteriovenous malformation surgery","volume":"67","author":"Fern\u00e1ndez-Miranda","year":"2010"},{"key":"b6-0370013","series-title":"J Neurosurg","first-page":"616","article-title":"Temporal lobe arteriovenous malformations: anatomical subtypes, surgical strategy, and outcomes. Clinical article","volume":"119","author":"Gabarr\u00f3s Canals","year":"2013"},{"key":"b7-0370013","series-title":"J Neurosurg","first-page":"331","article-title":"Bleeding from cerebral arteriovenous malformations as part of their natural history","volume":"58","author":"Graf","year":"1983"},{"key":"b8-0370013","series-title":"J Neurosurg","first-page":"437","article-title":"Natural history of cerebral arteriovenous malformations: a meta-analysis. Clinical article","volume":"118","author":"Gross","year":"2013"},{"key":"b9-0370013","series-title":"J Neurosurg","first-page":"44","article-title":"Arteriovenous malformations of the medial temporal lobe. Surgical approach and neuroradiological characterization","volume":"56","author":"Heros","year":"1982"},{"key":"b10-0370013","series-title":"Neurosurgery","first-page":"29","article-title":"Multimodality treatment of deep arteriovenous malformations: thalamus, basal ganglia, and brain stem","volume":"37","author":"Lawton","year":"1995"},{"key":"b11-0370013","series-title":"Neurosurgery","first-page":"29","article-title":"Sylvian fissure arteriovenous malformations: an application of the Sugita classification to 28 surgical patients","volume":"61","author":"Lawton","year":"2007"},{"key":"b12-0370013","series-title":"Neurosurgery","first-page":"740","article-title":"Spetzler-Martin Grade III arteriovenous malformations: surgical results and a modification of the grading scale","volume":"52","author":"Lawton","year":"2003"},{"key":"b13-0370013","series-title":"Neurosurg Rev","first-page":"541","article-title":"Sylvian fissure arteriovenous malformations: long-term prognosis and risk factors","volume":"36","author":"Liu","year":"2013"},{"key":"b14-0370013","series-title":"Neurosurgery","first-page":"854","article-title":"Temporal lobe arteriovenous malformations: surgical outcomes with a focus on visual field defects and epilepsy","volume":"73","author":"Lopez-Ojeda","year":"2013"},{"key":"b15-0370013","series-title":"Surg Neurol","first-page":"106","article-title":"Temporal lobe arteriovenous malformations: surgical management and outcome","volume":"46","author":"Malik","year":"1996"},{"key":"b16-0370013","series-title":"Lancet","first-page":"614","article-title":"Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial","volume":"383","author":"Mohr","year":"2014"},{"key":"b17-0370013","series-title":"J Neurointerv Surg","first-page":"150","article-title":"Transvenous embolization of a ruptured cerebral arteriovenous malformation with en-passage arterial supply: initial case report","volume":"2","author":"Nguyen","year":"2010"},{"key":"b18-0370013","series-title":"Neurol Med Chir (Tokyo)","first-page":"940","article-title":"Surgical approach to arteriovenous malformation of the medial temporal lobe\u2014report of three cases","volume":"30","author":"Oka","year":"1990"},{"key":"b19-0370013","series-title":"J Neurosurg","first-page":"467","article-title":"Report on the cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Section VI. Arteriovenous malformations. An analysis of 545 cases of cranio-cerebral arteriovenous malformations and fistulae reported to the cooperative study","volume":"25","author":"Perret","year":"1966"},{"key":"b20-0370013","series-title":"Neurosurgery","first-page":"824","article-title":"Transsylvian-transinsular approaches to the insula and basal ganglia: operative techniques and results with vascular lesions","volume":"70","author":"Potts","year":"2012"},{"key":"b21-0370013","series-title":"Neurosurgery","first-page":"417","article-title":"Deep arteriovenous malformations in the basal ganglia, thalamus, and insula: microsurgical management, techniques, and results","volume":"73","author":"Potts","year":"2013"},{"key":"b22-0370013","series-title":"J Neurosurg","first-page":"653","article-title":"Microsurgery for 67 intracranial arteriovenous malformations less than 3 cm in diameter","volume":"79","author":"Sisti","year":"1993"},{"key":"b23-0370013","series-title":"J Neurosurg","first-page":"476","article-title":"A proposed grading system for arteriovenous malformations","volume":"65","author":"Spetzler","year":"1986"},{"key":"b24-0370013","series-title":"J Neurosurg","first-page":"23","article-title":"Arteriovenous malformations of the medial cerebral hemisphere and the limbic system","volume":"60","author":"Stein","year":"1984"},{"key":"b25-0370013","series-title":"Neurosurgery","first-page":"7","article-title":"Sylvian fissure arteriovenous malformations","volume":"21","author":"Sugita","year":"1987"},{"key":"b26-0370013","series-title":"Zhonghua Yi Xue Za Zhi","first-page":"1609","article-title":"[Microsurgical treatment for sylvian fissure arteriovenous malformations.]","volume":"91","author":"Wang","year":"2011"},{"key":"b27-0370013","series-title":"Acta Neurochir (Wien)","first-page":"1565","article-title":"Resection of lateral temporal lobe arteriovenous malformations","volume":"155","author":"Williamson","year":"2013"},{"issue":"Suppl","key":"b28-0370013","series-title":"Neurol Med Chir (Tokyo)","first-page":"222","article-title":"Surgical techniques for arteriovenous malformations in functional areas: focus on the superior temporal gyrus","volume":"38","author":"Yamada","year":"1998"},{"key":"b29-0370013","series-title":"Microneurosurgery: AVM of the Brain, Clinical Considerations, General and Special Operative Techniques, Surgical Results, Nonoperated Cases, Cavernous and Venous Angiomas, Neuroanesthesia","first-page":"137","volume":"IIIB","author":"Yasargil","year":"1988"},{"key":"b30-0370013","series-title":"Arch Neurol","first-page":"1122","article-title":"Secondary epileptogenesis in cerebral arteriovenous malformations","volume":"48","author":"Yeh","year":"1991"},{"key":"b31-0370013","series-title":"J Neurosurg","first-page":"39","article-title":"Pure sylvian fissure arteriovenous malformations","volume":"92","author":"Zimmerman","year":"2000"},{"key":"b1-0370013","series-title":"Acta Neurochir (Wien)","first-page":"271","article-title":"The place for surgical treatment for AVM involving the temporal lobe","volume":"153","author":"Bostr\u00f6m","year":"2011"},{"key":"b2-0370013","series-title":"Neurosurgery","first-page":"804","article-title":"Functional magnetic resonance imaging and optical imaging for dominant-hemisphere perisylvian arteriovenous malformations","volume":"55","author":"Cannestra","year":"2004"},{"key":"b3-0370013","series-title":"J Neurosurg","first-page":"470","article-title":"Radiosurgery for ruptured intracranial arteriovenous malformations. Clinical article","volume":"121","author":"Ding","year":"2014"},{"key":"b4-0370013","series-title":"Neurosurgery","first-page":"645","article-title":"\u201cTangential\u201d resection of medial temporal lobe arteriovenous malformations with the orbitozygomatic approach","volume":"54","author":"Du","year":"2004"},{"issue":"3 Suppl Operative","key":"b5-0370013","series-title":"Neurosurgery","first-page":"ons237","article-title":"Microvascular anatomy of the medial temporal region: Part 1: its application to arteriovenous malformation surgery","volume":"67","author":"Fern\u00e1ndez-Miranda","year":"2010"},{"key":"b6-0370013","series-title":"J Neurosurg","first-page":"616","article-title":"Temporal lobe arteriovenous malformations: anatomical subtypes, surgical strategy, and outcomes. Clinical article","volume":"119","author":"Gabarr\u00f3s Canals","year":"2013"},{"key":"b7-0370013","series-title":"J Neurosurg","first-page":"331","article-title":"Bleeding from cerebral arteriovenous malformations as part of their natural history","volume":"58","author":"Graf","year":"1983"},{"key":"b8-0370013","series-title":"J Neurosurg","first-page":"437","article-title":"Natural history of cerebral arteriovenous malformations: a meta-analysis. Clinical article","volume":"118","author":"Gross","year":"2013"},{"key":"b9-0370013","series-title":"J Neurosurg","first-page":"44","article-title":"Arteriovenous malformations of the medial temporal lobe. Surgical approach and neuroradiological characterization","volume":"56","author":"Heros","year":"1982"},{"key":"b10-0370013","series-title":"Neurosurgery","first-page":"29","article-title":"Multimodality treatment of deep arteriovenous malformations: thalamus, basal ganglia, and brain stem","volume":"37","author":"Lawton","year":"1995"},{"key":"b11-0370013","series-title":"Neurosurgery","first-page":"29","article-title":"Sylvian fissure arteriovenous malformations: an application of the Sugita classification to 28 surgical patients","volume":"61","author":"Lawton","year":"2007"},{"key":"b12-0370013","series-title":"Neurosurgery","first-page":"740","article-title":"Spetzler-Martin Grade III arteriovenous malformations: surgical results and a modification of the grading scale","volume":"52","author":"Lawton","year":"2003"},{"key":"b13-0370013","series-title":"Neurosurg Rev","first-page":"541","article-title":"Sylvian fissure arteriovenous malformations: long-term prognosis and risk factors","volume":"36","author":"Liu","year":"2013"},{"key":"b14-0370013","series-title":"Neurosurgery","first-page":"854","article-title":"Temporal lobe arteriovenous malformations: surgical outcomes with a focus on visual field defects and epilepsy","volume":"73","author":"Lopez-Ojeda","year":"2013"},{"key":"b15-0370013","series-title":"Surg Neurol","first-page":"106","article-title":"Temporal lobe arteriovenous malformations: surgical management and outcome","volume":"46","author":"Malik","year":"1996"},{"key":"b16-0370013","series-title":"Lancet","first-page":"614","article-title":"Medical management with or without interventional therapy for unruptured brain arteriovenous malformations (ARUBA): a multicentre, non-blinded, randomised trial","volume":"383","author":"Mohr","year":"2014"},{"key":"b17-0370013","series-title":"J Neurointerv Surg","first-page":"150","article-title":"Transvenous embolization of a ruptured cerebral arteriovenous malformation with en-passage arterial supply: initial case report","volume":"2","author":"Nguyen","year":"2010"},{"key":"b18-0370013","series-title":"Neurol Med Chir (Tokyo)","first-page":"940","article-title":"Surgical approach to arteriovenous malformation of the medial temporal lobe\u2014report of three cases","volume":"30","author":"Oka","year":"1990"},{"key":"b19-0370013","series-title":"J Neurosurg","first-page":"467","article-title":"Report on the cooperative study of intracranial aneurysms and subarachnoid hemorrhage. Section VI. Arteriovenous malformations. An analysis of 545 cases of cranio-cerebral arteriovenous malformations and fistulae reported to the cooperative study","volume":"25","author":"Perret","year":"1966"},{"key":"b20-0370013","series-title":"Neurosurgery","first-page":"824","article-title":"Transsylvian-transinsular approaches to the insula and basal ganglia: operative techniques and results with vascular lesions","volume":"70","author":"Potts","year":"2012"},{"key":"b21-0370013","series-title":"Neurosurgery","first-page":"417","article-title":"Deep arteriovenous malformations in the basal ganglia, thalamus, and insula: microsurgical management, techniques, and results","volume":"73","author":"Potts","year":"2013"},{"key":"b22-0370013","series-title":"J Neurosurg","first-page":"653","article-title":"Microsurgery for 67 intracranial arteriovenous malformations less than 3 cm in diameter","volume":"79","author":"Sisti","year":"1993"},{"key":"b23-0370013","series-title":"J Neurosurg","first-page":"476","article-title":"A proposed grading system for arteriovenous malformations","volume":"65","author":"Spetzler","year":"1986"},{"key":"b24-0370013","series-title":"J Neurosurg","first-page":"23","article-title":"Arteriovenous malformations of the medial cerebral hemisphere and the limbic system","volume":"60","author":"Stein","year":"1984"},{"key":"b25-0370013","series-title":"Neurosurgery","first-page":"7","article-title":"Sylvian fissure arteriovenous malformations","volume":"21","author":"Sugita","year":"1987"},{"key":"b26-0370013","series-title":"Zhonghua Yi Xue Za Zhi","first-page":"1609","article-title":"[Microsurgical treatment for sylvian fissure arteriovenous malformations.]","volume":"91","author":"Wang","year":"2011"},{"key":"b27-0370013","series-title":"Acta Neurochir (Wien)","first-page":"1565","article-title":"Resection of lateral temporal lobe arteriovenous malformations","volume":"155","author":"Williamson","year":"2013"},{"issue":"Suppl","key":"b28-0370013","series-title":"Neurol Med Chir (Tokyo)","first-page":"222","article-title":"Surgical techniques for arteriovenous malformations in functional areas: focus on the superior temporal gyrus","volume":"38","author":"Yamada","year":"1998"},{"key":"b29-0370013","series-title":"Microneurosurgery: AVM of the Brain, Clinical Considerations, General and Special Operative Techniques, Surgical Results, Nonoperated Cases, Cavernous and Venous Angiomas, Neuroanesthesia","first-page":"137","volume":"IIIB","author":"Yasargil","year":"1988"},{"key":"b30-0370013","series-title":"Arch Neurol","first-page":"1122","article-title":"Secondary epileptogenesis in cerebral arteriovenous malformations","volume":"48","author":"Yeh","year":"1991"},{"key":"b31-0370013","series-title":"J Neurosurg","first-page":"39","article-title":"Pure sylvian fissure arteriovenous malformations","volume":"92","author":"Zimmerman","year":"2000"}],"container-title":["Neurosurgical Focus"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus\/37\/3\/article-pE13.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus\/37\/3\/article-pE13.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/neurosurg-focus\/37\/3\/article-pE13.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T08:42:30Z","timestamp":1780130550000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/neurosurg-focus\/37\/3\/article-pE13.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2014,9]]},"references-count":62,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2014.7.focus14246","relation":{},"ISSN":["1092-0684"],"issn-type":[{"value":"1092-0684","type":"electronic"}],"subject":[],"published":{"date-parts":[[2014,9]]}}}