{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T16:40:28Z","timestamp":1681576828978},"reference-count":15,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2014,11]]},"abstract":"\nObject<\/jats:title>\nPolyethylene glycol (PEG) sealant in conjunction with standard closure techniques is effective in preventing CSF leaks after cranial procedures in adult patients, but the safety of PEG sealant in the pediatric population has not been shown.<\/jats:p><\/jats:sec>\n\nMethods<\/jats:title>\nThe authors performed a retrospective analysis of pediatric neurosurgery patients (0\u201318 years of age) treated from 2005 to 2010 at The Johns Hopkins Hospital. There were 163 patients who underwent cranial surgery with the use of PEG sealant as an adjunct to standard closure techniques. There were 92 males and 71 females with an average age of 10.2 years. The incidences of revision surgery, CSF leak, meningitis, and neurological deficit were recorded.<\/jats:p><\/jats:sec>\n\nResults<\/jats:title>\nIn the cohort's 90-day postoperative clinical course, the authors found that 4 patients (2.5%) required revision surgery, 2 patients (1.2%) developed a CSF leak, 4 patients (2.5%) developed a superficial skin infection, and 1 patient developed meningitis (0.6%) with no deaths or neurological deficits observed.<\/jats:p><\/jats:sec>\n\nConclusions<\/jats:title>\nPEG sealant appears to be a safe adjunct to standard dural closure in pediatric cranial surgery patients to augment dural closure.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2014.7.peds1437","type":"journal-article","created":{"date-parts":[[2014,9,5]],"date-time":"2014-09-05T14:12:06Z","timestamp":1409926326000},"page":"514-517","source":"Crossref","is-referenced-by-count":1,"title":["Evaluation of complication rates of pediatric cranial procedures in which a polyethylene glycol sealant was used"],"prefix":"10.3171","volume":"14","author":[{"given":"Xin","family":"Zhou","sequence":"first","affiliation":[{"name":"Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"C. Rory","family":"Goodwin","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Pablo F.","family":"Recinos","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"},{"name":"Department of Neurosurgery, Cleveland Clinic Foundation, Cleveland, Ohio"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jesse X.","family":"Yang","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George I.","family":"Jallo","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Johns Hopkins University School of Medicine, Baltimore, Maryland; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-peds1437","series-title":"National Neurosurgical Procedural Statistics, 2006 Survey","author":"American Association of Neurological Surgeons","year":"2008"},{"issue":"1 Suppl","key":"b2-peds1437","series-title":"Neurosurgery","first-page":"146","article-title":"Use of a novel absorbable hydrogel for augmentation of dural repair: results of a preliminary clinical study","volume":"57","author":"Boogaarts","year":"2005"},{"issue":"389","key":"b3-peds1437","series-title":"Clin Orthop Relat Res","first-page":"238","article-title":"Evaluation and treatment of dural tears in lumbar spine surgery: a review","author":"Bosacco","year":"2001"},{"key":"b4-peds1437","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"227","DOI":"10.3171\/2012.10.PEDS12160","article-title":"Endoscopic endonasal skull base surgery in the pediatric population. 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Clinical article","volume":"13","author":"Goodwin","year":"2014"},{"key":"b8-peds1437","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"490","DOI":"10.1016\/j.surneu.2005.03.041","article-title":"Costs of postoperative cerebrospinal fluid leakage: 1-year, retrospective analysis of 412 consecutive nontrauma cases","volume":"64","author":"Grotenhuis","year":"2005"},{"key":"b9-peds1437","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"498","DOI":"10.1016\/j.wneu.2011.12.011","article-title":"A multicenter, single-blind, prospective randomized trial to evaluate the safety of a polyethylene glycol hydrogel (Duraseal Dural Sealant System) as a dural sealant in cranial surgery","volume":"78","author":"Osbun","year":"2012"},{"key":"b10-peds1437","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"177","DOI":"10.3171\/2011.5.PEDS10362","article-title":"Complications following decompression of Chiari malformation Type I in children: dural graft or sealant? Clinical article","volume":"8","author":"Parker","year":"2011"},{"issue":"3 Suppl","key":"b11-peds1437","series-title":"J Neurosurg","first-page":"187","article-title":"Complications and pitfalls of neuroendoscopic surgery in children","volume":"105","author":"Peretta","year":"2006"},{"key":"b12-peds1437","series-title":"Neurochirurgia (Stuttg)","first-page":"166","article-title":"The use of fibrin sealant in cerebrospinal fluid leakage","volume":"34","author":"Pomeranz","year":"1991"},{"issue":"1 Suppl","key":"b13-peds1437","series-title":"Neurosurgery","first-page":"ONS182","article-title":"Polyethylene glycol hydrogel dural sealant may reduce incisional cerebrospinal fluid leak after posterior fossa surgery","volume":"63","author":"Than","year":"2008"},{"key":"b14-peds1437","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"107","DOI":"10.3171\/2013.9.PEDS13222","article-title":"Prospective review of a single center's general pediatric neurosurgical intraoperative and postoperative complication rates. Clinical article","volume":"13","author":"van Lindert","year":"2014"},{"key":"b15-peds1437","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"428","DOI":"10.3171\/2009.6.JNS081540","article-title":"The safety and effectiveness of a dural sealant system for use with nonautologous duraplasty materials. 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