{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2025,11,5]],"date-time":"2025-11-05T14:19:11Z","timestamp":1762352351110},"reference-count":20,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2014,11]]},"abstract":"\nObject<\/jats:title>\nDespite its potential clinical impact, information regarding progression of thoracic ossification of the posterior longitudinal ligament (OPLL) is scarce. Posterior decompression with stabilization is currently the primary surgical treatment for symptomatic thoracic OPLL; however, it remains unclear whether thoracic OPLL increases in size following spinal stabilization. It is also unknown whether patients' clinical symptoms worsen as OPLL size increases. In this retrospective case series study, the authors examined the postoperative progression of thoracic OPLL.<\/jats:p><\/jats:sec>\n\nMethods<\/jats:title>\nNine consecutive patients with thoracic OPLL who underwent posterior decompression and fixation with a minimum follow-up of 3 years were included in this study. Thin-slice CT scans of the thoracic spine obtained at the time of surgery and the most recent follow-up were analyzed. The level of the most obvious protrusion of ossification was determined using the sagittal reconstructions, and the ossified area was measured on the axial reconstructed scan at the level of the most obvious protrusion of ossification using the DICOM (digital imaging and communications in medicine) software program. Myelopathy severity was assessed according to the Japanese Orthopaedic Association (JOA) scale score for lower-limb motor function on admission, at postoperative discharge, and at the last follow-up visit.<\/jats:p><\/jats:sec>\n\nResults<\/jats:title>\nThe OPLL area was increased in all patients. The mean area of ossification increased from 83.6 \u00b1 25.3 mm2<\/jats:sup> at the time of surgery to 114.8 \u00b1 32.4 mm2<\/jats:sup> at the last follow-up visit. No patients exhibited any neurological deterioration due to OPLL progression.<\/jats:p><\/jats:sec>\n\nConclusions<\/jats:title>\nThe present study demonstrated that the size of the thoracic OPLL increased after spinal stabilization. Despite diminished local spinal motion, OPLL progression did not decrease or stop. Physicians should pay attention to ossification progression in patients with thoracic OPLL.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2014.7.spine131191","type":"journal-article","created":{"date-parts":[[2014,8,15]],"date-time":"2014-08-15T16:42:52Z","timestamp":1408120972000},"page":"773-777","source":"Crossref","is-referenced-by-count":10,"title":["Progression of ossification of the posterior longitudinal ligament of the thoracic spine following posterior decompression and stabilization"],"prefix":"10.3171","volume":"21","author":[{"given":"Shurei","family":"Sugita","sequence":"first","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo ; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hirotaka","family":"Chikuda","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo ; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Katsushi","family":"Takeshita","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo ; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Atsushi","family":"Seichi","sequence":"additional","affiliation":[{"name":"Department of Orthopedics, Jichi Medical University, Tochigi, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Sakae","family":"Tanaka","sequence":"additional","affiliation":[{"name":"Department of Orthopaedic Surgery, Faculty of Medicine, University of Tokyo, Tokyo ; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-spine131191","series-title":"J Neurosurg Spine","doi-asserted-by":"publisher","first-page":"512","DOI":"10.3171\/2012.9.SPINE12548","article-title":"Does ossification of the posterior longitudinal ligament progress after laminoplasty? 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