{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,2,12]],"date-time":"2026-02-12T08:53:18Z","timestamp":1770886398429,"version":"3.50.1"},"reference-count":13,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2014,12]]},"abstract":"<jats:p>Vertebral cystic lesions may be observed in pseudarthroses after lumbar fusion surgery. The authors report a rare case of pseudarthrosis after spinal fusion, accompanied by an expanding vertebral osteolytic defect induced by cellulose particles. A male patient originally presented at the age of 69 years with leg and low-back pain caused by a lumbar isthmic spondylolisthesis. He underwent a posterior lumbar interbody fusion, and his neurological symptoms and pain resolved within a year but recurred 14 months after surgery. Radiological imaging demonstrated a cystic lesion on the inferior endplate of L-5 and the superior endplate of S-1, which rapidly enlarged into a vertebral osteolytic defect. The patient underwent revision surgery, and his low-back pain resolved. A histopathological examination demonstrated foreign body\u2013type multinucleated giant cells, containing 10-\u03bcm particles, in the sample collected just below the defect. Micro\u2013Fourier transform infrared spectroscopy revealed that the foreign particles were cellulosic, presumably originating from cotton gauze fibers that had contaminated the interbody cages used during the initial surgery. Vertebral osteolytic defects that occur after interbody fusion are generally presumed to be the result of infection. This case suggests that some instances of vertebral osteolytic defects may be aseptically induced by foreign particles. Hence, this possibility should be carefully considered in such cases, to help prevent contamination of the morselized bone used for autologous grafts by foreign materials, such as gauze fibers.<\/jats:p>","DOI":"10.3171\/2014.8.spine14196","type":"journal-article","created":{"date-parts":[[2014,9,26]],"date-time":"2014-09-26T15:21:00Z","timestamp":1411744860000},"page":"877-881","source":"Crossref","is-referenced-by-count":3,"title":["Vertebral osteolytic defect due to cellulose particles derived from gauze fibers after posterior lumbar interbody fusion"],"prefix":"10.3171","volume":"21","author":[{"given":"Shota","family":"Takenaka","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshihiro","family":"Mukai","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Noboru","family":"Hosono","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kosuke","family":"Tateishi","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Takeshi","family":"Fuji","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-spine14196","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1437","DOI":"10.1097\/00007632-200006010-00017","article-title":"Lumbar interbody fusion using the Brantigan I\/F cage for posterior lumbar interbody fusion and the variable pedicle screw placement system: two-year results from a Food and Drug Administration investigational device exemption clinical trial","volume":"25","author":"Brantigan","year":"2000"},{"key":"b2-spine14196","series-title":"Acta Orthop Scand","doi-asserted-by":"publisher","first-page":"554","DOI":"10.1080\/00016470410001411","article-title":"The cause of subchondral bone cysts in osteoarthrosis: a finite element analysis","volume":"75","author":"D\u00fcrr","year":"2004"},{"key":"b3-spine14196","series-title":"Orthop Clin North Am","doi-asserted-by":"publisher","first-page":"381","DOI":"10.1016\/S0030-5898(02)00005-6","article-title":"Revision strategies for lumbar pseudarthrosis","volume":"33","author":"Etminan","year":"2002"},{"key":"b4-spine14196","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s00586-011-2002-4","article-title":"Osteolysis following resorbable poly-L-lactide-co-D, L-lactide PLIF cage use: a review of cases","volume":"21","author":"Frost","year":"2012"},{"key":"b5-spine14196","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"E1197","DOI":"10.1097\/BRS.0b013e31825d26d7","article-title":"Does the formation of vertebral endplate cysts predict nonunion after lumbar interbody fusion?","volume":"37","author":"Fujibayashi","year":"2012"},{"key":"b6-spine14196","series-title":"Instr Course Lect","first-page":"201","article-title":"The basic science of periprosthetic osteolysis","volume":"62","author":"Goodman","year":"2013"},{"key":"b7-spine14196","series-title":"Fourier Transform Infrared Spectrometry","first-page":"1","article-title":"Introduction to vibrational spectroscopy","author":"Griffiths","year":"2007"},{"key":"b8-spine14196","series-title":"J Jpn Orthop Assoc","first-page":"391","article-title":"[Assessment of treatment for low back pain]","volume":"60","author":"Izumida","year":"1986"},{"key":"b9-spine14196","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"233","DOI":"10.1097\/BRS.0b013e318194ed00","article-title":"Posterior lumbar interbody fusion using nonresorbable poly-ether-ether-ketone versus resorbable poly-L-lactide-co-D,L-lactide fusion devices: a prospective, randomized study to assess fusion and clinical outcome","volume":"34","author":"Jiya","year":"2009"},{"key":"b10-spine14196","series-title":"J Biomed Mater Res","doi-asserted-by":"publisher","first-page":"363","DOI":"10.1002\/(SICI)1097-4636(19990615)45:4<363::AID-JBM11>3.0.CO;2-3","article-title":"Histiocyte reaction in rabbit femurs to UHMWPE, metal, and ceramic particles in different sizes","volume":"45","author":"Kubo","year":"1999"},{"key":"b11-spine14196","series-title":"J Bone Joint Surg Br","first-page":"10","article-title":"Current concepts in osteolysis","volume":"94","author":"Ollivere","year":"2012"},{"key":"b12-spine14196","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"150","DOI":"10.1097\/BRS.0b013e3182154c22","article-title":"Are periprosthetic tissue reactions observed after revision of total disc replacement comparable to the reactions observed after total hip or knee revision surgery?","volume":"37","author":"Punt","year":"2012"},{"key":"b13-spine14196","series-title":"J Biomed Mater Res","doi-asserted-by":"publisher","first-page":"81","DOI":"10.1002\/jbm.820280111","article-title":"Macrophage\/particle interactions: effect of size, composition and surface area","volume":"28","author":"Shanbhag","year":"1994"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/21\/6\/article-p877.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/21\/6\/article-p877.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/21\/6\/article-p877.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T23:05:41Z","timestamp":1681599941000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/21\/6\/article-p877.xml"}},"subtitle":["Case report"],"short-title":[],"issued":{"date-parts":[[2014,12]]},"references-count":13,"journal-issue":{"issue":"6"},"URL":"https:\/\/doi.org\/10.3171\/2014.8.spine14196","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2014,12]]}}}