{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,18]],"date-time":"2026-08-18T04:02:24Z","timestamp":1787025744367,"version":"build-2736575974"},"reference-count":25,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2014,11]]},"abstract":"<jats:p>Patients with Marfan syndrome used to succumb early in life from cardiovascular complications. With the current rapid advance in medical and surgical care, such patients may now have near-normal longevities. Consequently, rare late-life complications are emerging in these patients and represent challenges to clinicians for their diagnoses and treatments. The authors report a rare case of pelvic pain and genital prolapse from a giant presacral Tarlov cyst in a 67-year-old patient with Marfan syndrome.<\/jats:p>\n                  <jats:p>This 67-year-old Caucasian female presented with progressively severe pelvic pain, intermittent explosive diarrhea, and dysuria. Physical and bimanual examination demonstrated genital prolapse and a nontender, cyst-like mass fixed in the midline. She underwent ultrasound, CT, and eventually MRI evaluations that led to the diagnosis of a giant (6.7 \u00d7 6.4 \u00d7 6.6 cm) Tarlov cyst originating from the right S-2 nerve root sleeve\/sacral foramen with intrapelvic extension. She underwent S1\u2013S2 and S2\u2013S3 laminectomy with obliteration of the Tarlov cyst using aneurysm clips. Postoperatively, her pelvic pain and bowel symptoms resolved and the bladder symptoms improved. The 3-month follow-up CT of abdomen\/pelvis demonstrated resolution of the cyst.<\/jats:p>\n                  <jats:p>The present case illustrates that clinicians caring for elderly patients with Marfan syndrome need to increasingly recognize such unusual late-life complications. Also, these large Tarlov cysts can be simply and effectively obliterated with aneurysm clips.<\/jats:p>","DOI":"10.3171\/2014.8.spine148","type":"journal-article","created":{"date-parts":[[2014,11,1]],"date-time":"2014-11-01T04:25:08Z","timestamp":1414815908000},"page":"833-836","source":"Crossref","is-referenced-by-count":13,"title":["Pelvic pain from a giant presacral Tarlov cyst successfully obliterated using aneurysm clips in a patient with Marfan syndrome"],"prefix":"10.3171","volume":"21","author":[{"given":"Bonnie","family":"Wang","sequence":"first","affiliation":[{"name":"Departments of Internal Medicine and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seong-Jin","family":"Moon","sequence":"additional","affiliation":[{"name":"University of Illinois College of Medicine, Urbana, Illinois"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William C.","family":"Olivero","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Huan","family":"Wang","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-spine148","series-title":"J Spinal Cord Med","doi-asserted-by":"publisher","first-page":"499","DOI":"10.1179\/2045772312Y.0000000079","article-title":"Marfan syndrome and symptomatic sacral cyst: report of two cases","volume":"36","author":"Arnold","year":"2013"},{"key":"b2-spine148","series-title":"Nat Rev Cardiol","doi-asserted-by":"publisher","first-page":"256","DOI":"10.1038\/nrcardio.2010.30","article-title":"Marfan syndrome. 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