{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,8]],"date-time":"2026-10-08T19:55:09Z","timestamp":1791489309728,"version":"4.3.4"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2017,1]]},"abstract":"\nOBJECTIVE<\/jats:title>\nThere are no guidelines for the management of postoperative lateral sinus thrombosis following posterior fossa surgery. Introducing treatment-dose anticoagulant therapy during the immediate postoperative period increases the risk of intracranial bleeding. This study assessed the incidence of and risk factors associated with postoperative lateral sinus thrombosis and the complications related to thrombosis and\/or anticoagulation.<\/jats:p><\/jats:sec>\n\nMETHODS<\/jats:title>\nThis study was a retrospective monocentric analysis of adult patients who underwent surgical removal of a posterior fossa space-occupying lesion with available postoperative imaging. Postoperative lateral sinus thrombosis was defined as a T2*<\/jats:sup> hypointensity within the venous sinus and\/or a filling defect on postcontrast MRI or CT scan.<\/jats:p><\/jats:sec>\n\nRESULTS<\/jats:title>\nAmong 180 patients, 12 (6.7%; 95% CI 3.0\u201310.4) were found to have lateral sinus thrombosis on postoperative imaging, none of whom were symptomatic. Unadjusted risk factors for postoperative lateral sinus thrombosis were a history of deep venous thrombosis (p = 0.016), oral contraceptive pill (p = 0.004), midline surgical approach (p = 0.035), and surgical exposure of the sinus (p < 0.001). Seven of the patients (58.3%) with a postoperative lateral sinus thrombosis received immediate treatment-dose anticoagulant therapy. Lateral sinus recanalization occurred radiologically at a mean time of 272 \u00b1 23 days in 85.7% of patients (6 of 7) undergoing treatment-dose anticoagulant therapy and in 20% of patients (1 of 5) not receiving treatment-dose anticoagulant therapy. Postoperative complications occurred in 56.2% of patients (9 of 16) who received treatment-dose curative anticoagulant therapy and in 27% of patients (45 of 164) who did not.<\/jats:p><\/jats:sec>\n\nCONCLUSIONS<\/jats:title>\nIncidental radiological lateral sinus thrombosis following posterior fossa surgery has an incidence of 6.7%. To further define the benefit-to-risk ratio of a treatment-dose anticoagulant therapy, a prospective trial should be considered.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2015.11.jns151881","type":"journal-article","created":{"date-parts":[[2016,2,26]],"date-time":"2016-02-26T15:05:01Z","timestamp":1456499101000},"page":"8-16","source":"Crossref","is-referenced-by-count":28,"title":["Presentation and management of lateral sinus thrombosis following posterior fossa surgery"],"prefix":"10.3171","volume":"126","author":[{"given":"Caroline","family":"Apra","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Owais","family":"Kotbi","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neuroradiology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guillaume","family":"Turc","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neurology,"},{"name":"INSERM U894, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert","family":"Corns","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Leeds General Infirmary, Leeds, United Kingdom"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"M\u00e9lanie","family":"Pag\u00e8s","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neuropathology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Rapha\u00eblle","family":"Souillard-Sc\u00e9mama","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neuroradiology,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edouard","family":"Dezamis","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Eduardo","family":"Parraga","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean-Fran\u00e7ois","family":"Meder","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neuroradiology,"},{"name":"INSERM U894, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Xavier","family":"Sauvageon","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neuro-Anaesthesia and Neuro-Intensive Care, Sainte-Anne Hospital;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Bertrand","family":"Devaux","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Oppenheim","sequence":"additional","affiliation":[{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"},{"name":"Neuroradiology,"},{"name":"INSERM U894, Paris, France; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Johan","family":"Pallud","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery,"},{"name":"Paris Descartes University, Sorbonne Paris Cit\u00e9;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"4","key":"b1-jns151881","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E1","DOI":"10.3171\/foc.2004.17.4.1","article-title":"Prophylaxis for deep venous thrombosis in neurosurgery: a review of the literature","volume":"17","author":"Browd SR,","year":"2004","unstructured":"Browd SR, Ragel BT, Davis GE, Scott AM, Skalabrin EJ, Couldwell WT: Prophylaxis for deep venous thrombosis in neurosurgery: a review of the literature. 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