{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,8,23]],"date-time":"2026-08-23T16:47:13Z","timestamp":1787503633981,"version":"build-2736575974"},"reference-count":68,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2015,5]]},"abstract":"\n OBJECT<\/jats:title>\n The authors\u2019 aim was perform a systematic review on the incidence of intracranial hypertension (IH) after surgery for craniosynostosis.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n A systematic literature review was conducted using PubMed to assess the rate of postoperative IH in studies published between 1985 and 2014. Inclusion criteria were 1) English-language literature; 2) human subjects; 3) pediatric cases; and 4) postoperative IH confirmed with invasive intracranial pressure monitoring.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n Seven studies met inclusion criteria. IH was reported to be present in 5% of patients postoperatively with sagittal synostosis and 4% of patients with all forms of nonsyndromic craniosynostosis. Inadequate numbers were available to determine the incidence of postoperative IH for syndromic and individual nonsyndromic sutural synostosis based on the inclusion criteria. Surgical groups were subdivided into cranial remodeling procedures without orbital advancement and craniofacial procedures with orbital advancement. IH was reported to be present in 5% of patients with all forms of nonsyndromic sutural stenosis after cranial remodeling procedures and 1% after craniofacial advancement.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n Postoperative development of elevated intracranial pressure has been described by multiple institutions, but the variation in how IH is determined and the multiple surgical procedures to correct craniosynostosis has limited the number of studies subject to a meta-analysis. Nonetheless, this entity deserves special attention, and further studies are required to determine the true incidence of postoperative IH, including the role of various surgical procedures on its incidence. The long-term consequences of chronic IH in this group of patients also need to be evaluated.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2015.2.focus14853","type":"journal-article","created":{"date-parts":[[2015,5,1]],"date-time":"2015-05-01T03:36:59Z","timestamp":1430451419000},"page":"E6","source":"Crossref","is-referenced-by-count":30,"title":["Intracranial hypertension after surgical correction for craniosynostosis: a systematic review"],"prefix":"10.3171","volume":"38","author":[{"given":"Eisha A.","family":"Christian","sequence":"first","affiliation":[{"name":"Divisions of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas A.","family":"Imahiyerobo","sequence":"additional","affiliation":[{"name":"Plastic Surgery, Children\u2019s Hospital Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Swathi","family":"Nallapa","sequence":"additional","affiliation":[{"name":"Divisions of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark","family":"Urata","sequence":"additional","affiliation":[{"name":"Plastic Surgery, Children\u2019s Hospital Los Angeles, California"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"J. Gordon","family":"McComb","sequence":"additional","affiliation":[{"name":"Divisions of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark D.","family":"Krieger","sequence":"additional","affiliation":[{"name":"Divisions of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-focus14853","series-title":"J Neurosurg Pediatr","first-page":"131","article-title":"A single-center experience with symptomatic postoperative calvarial growth restriction after extended strip craniectomy for sagittal craniosynostosis","volume":"5","author":"Adamo","year":"2010"},{"issue":"Suppl 2","key":"b2-focus14853","series-title":"J Craniofac Surg","first-page":"1843","article-title":"Scaphocephaly part II: Secondary coronal synostosis after scaphocephalic surgical correction","volume":"20","author":"Arnaud","year":"2009"},{"key":"b3-focus14853","series-title":"J Neurosurg","first-page":"476","article-title":"Prognosis for mental function in scaphocephaly","volume":"83","author":"Arnaud","year":"1995"},{"key":"b4-focus14853","series-title":"J Craniofac Surg","first-page":"121","article-title":"Papilledema in patients with Apert, Crouzon, and Pfeiffer syndrome: prevalence, efficacy of treatment, and risk factors","volume":"19","author":"Bannink","year":"2008"},{"key":"b5-focus14853","series-title":"Biomed Res Int","first-page":"172646","article-title":"Role of 99mTc-ECD SPECT in the management of children with craniosynostosis","volume":"2014","author":"Barik","year":"2014"},{"key":"b6-focus14853","series-title":"Pediatr Neurosurg","first-page":"270","article-title":"Intracranial hypertension after cranial vault decompression for craniosynostosis","volume":"22","author":"Campbell","year":"1995"},{"key":"b7-focus14853","series-title":"J Neurosurg Pediatr","first-page":"661","article-title":"Delayed intracranial hypertension after cranial vault remodeling for nonsyndromic single-suture synostosis","volume":"11","author":"Cetas","year":"2013"},{"key":"b8-focus14853","series-title":"J Craniofac Surg","first-page":"167","article-title":"Surgical techniques of cranial vault expansion for increases in intracranial pressure in older children","volume":"4","author":"Cohen","year":"1993"},{"key":"b9-focus14853","series-title":"Cleft Palate Craniofac J","first-page":"194","article-title":"Intracranial pressure in single-suture craniosynostosis","volume":"35","author":"Cohen","year":"1998"},{"key":"b10-focus14853","series-title":"J Craniofac Surg","first-page":"177","article-title":"Cerebral perfusion defects secondary to simple craniosynostosis","volume":"7","author":"David","year":"1996"},{"key":"b11-focus14853","series-title":"Childs Nerv Syst","first-page":"1327","article-title":"Scaphocephaly correction with retrocoronal and prelambdoid craniotomies (Renier\u2019s \u201cH\u201d technique)","volume":"28","author":"Di Rocco","year":"2012"},{"key":"b12-focus14853","series-title":"Pediatr Neurosurg","first-page":"472","article-title":"Is intracranial pressure waveform analysis useful in the management of pediatric neurosurgical patients?","volume":"43","author":"Eide","year":"2007"},{"key":"b13-focus14853","series-title":"Pediatr Neurosurg","first-page":"310","article-title":"Assessment of continuous intracranial pressure recordings in childhood craniosynostosis","volume":"37","author":"Eide","year":"2002"},{"key":"b14-focus14853","series-title":"Plast Reconstr Surg","first-page":"70e","article-title":"Recurrence of synostosis following surgical repair of craniosynostosis","volume":"121","author":"Foster","year":"2008"},{"key":"b15-focus14853","series-title":"Plast Reconstr Surg","first-page":"491","article-title":"The effects of whole-vault cranioplasty versus strip craniectomy on long-term neuropsychological outcomes in sagittal craniosynostosis","volume":"134","author":"Hashim","year":"2014"},{"key":"b16-focus14853","series-title":"Cleft Palate Craniofac J","first-page":"167","article-title":"Multiple suture synostosis and increased intracranial pressure following repair of single suture, nonsyndromal craniosynostosis","volume":"35","author":"Hudgins","year":"1998"},{"key":"b17-focus14853","series-title":"Acta Psychiatr Neurol Scand Suppl","first-page":"1","article-title":"Continuous recording and control of ventricular fluid pressure in neurosurgical practice","volume":"36","author":"Lundberg","year":"1960"},{"key":"b18-focus14853","series-title":"Br J Plast Surg","first-page":"1","article-title":"Experience with the \u201cfloating forehead.\u201d","volume":"41","author":"Marchac","year":"1988"},{"key":"b19-focus14853","series-title":"Plast Reconstr Surg","first-page":"217","article-title":"Implications of a vertex bulge following modified strip craniectomy for sagittal 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correlation between intracranial pressure, cranial radiographs, and computed tomographic scans in children with craniosynostosis","volume":"39","author":"Tuite","year":"1996"},{"key":"b33-focus14853","series-title":"Childs Nerv Syst","first-page":"997","article-title":"Results of early surgery for sagittal suture synostosis: long-term follow-up and the occurrence of raised intracranial pressure","volume":"29","author":"van Veelen","year":"2013"},{"key":"b34-focus14853","series-title":"Br J Plast Surg","first-page":"180","article-title":"Fronto-orbital re-operation in craniosynostosis","volume":"47","author":"Wall","year":"1994"},{"key":"b1-focus14853","series-title":"J Neurosurg Pediatr","first-page":"131","article-title":"A single-center experience with symptomatic postoperative calvarial growth restriction after extended strip craniectomy for sagittal craniosynostosis","volume":"5","author":"Adamo","year":"2010"},{"issue":"Suppl 2","key":"b2-focus14853","series-title":"J Craniofac 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Neurosurg","first-page":"202","article-title":"Incidence of increased intracranial pressure after early surgical treatment of syndromic craniosynostosis","volume":"24","author":"Pollack","year":"1996"},{"key":"b24-focus14853","series-title":"Invest Ophthalmol Vis Sci","first-page":"5197","article-title":"Follow-up of mild papilledema in idiopathic intracranial hypertension with optical coherence tomography","volume":"50","author":"Rebolleda","year":"2009"},{"key":"b25-focus14853","series-title":"Neurosurgery","first-page":"442","article-title":"Delayed and progressive multiple suture craniosynostosis","volume":"26","author":"Reddy","year":"1990"},{"key":"b26-focus14853","series-title":"Childs Nerv Syst","first-page":"645","article-title":"Management of craniosynostoses","volume":"16","author":"Renier","year":"2000"},{"key":"b27-focus14853","series-title":"J Neurosurg","first-page":"370","article-title":"Intracranial pressure in craniostenosis","volume":"57","author":"Renier","year":"1982"},{"key":"b28-focus14853","series-title":"Neurosurgery","first-page":"703","article-title":"The detection and management of intracranial hypertension after initial suture release and decompression for craniofacial dysostosis syndromes","volume":"36","author":"Siddiqi","year":"1995"},{"key":"b29-focus14853","series-title":"J Pediatr Psychol","first-page":"651","article-title":"Single-suture craniosynostosis: a review of neurobehavioral research and theory","volume":"29","author":"Speltz","year":"2004"},{"key":"b30-focus14853","series-title":"Childs Nerv Syst","first-page":"269","article-title":"Subdural intracranial pressure monitoring in craniosynostosis: its role in surgical management","volume":"11","author":"Thompson","year":"1995"},{"key":"b31-focus14853","series-title":"Neurosurgery","first-page":"272","article-title":"The effectiveness of papilledema as an indicator of raised intracranial pressure in children with 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