{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,27]],"date-time":"2026-03-27T02:00:17Z","timestamp":1774576817892,"version":"3.50.1"},"reference-count":71,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec>\n<jats:title>OBJECT<\/jats:title>\n<jats:p>The cerebral isthmus is the white matter area located between the periinsular sulcus and the lateral ventricle. Studies demonstrating the fiber tract and topographic anatomy of this entity are lacking in current neurosurgical literature. Hence, the authors\u2019 primary aim was to describe the microsurgical white matter anatomy of the cerebral isthmus by using the fiber dissection technique, and they discuss its functional significance. In addition, they sought to investigate its possible surgical utility in approaching lesions located in or adjacent to the lateral ventricle.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>This study was divided into 2 parts and included 30 formalin-fixed cerebral hemispheres, 5 of which were injected with colored silicone. In the first part, 15 uncolored specimens underwent the Klinger\u2019s procedure and were dissected in a lateromedial direction at the level of the superior, inferior, and anterior isthmuses, and 10 were used for coronal and axial cuts. In the second part, the injected specimens were used to investigate the surgical significance of the superior isthmus in accessing the frontal horn of the lateral ventricle.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>The microsurgical anatomy of the anterior, superior, and inferior cerebral isthmuses was carefully studied and recorded both in terms of topographic and fiber tract anatomy. In addition, the potential role of the proximal part of the superior isthmus as an alternative safe surgical corridor to the anterior part of the lateral ventricle was investigated.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>Using the fiber dissection technique along with coronal and axial cuts in cadaveric brain specimens remains a cornerstone in the acquisition of thorough anatomical knowledge of narrow white matter areas such as the cerebral isthmus. The surgical significance of the superior isthmus in approaching the frontal horn of the lateral ventricle is stressed, but further studies must be carried out to elucidate its role in ventricular surgery.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2015.3.jns142680","type":"journal-article","created":{"date-parts":[[2015,9,11]],"date-time":"2015-09-11T14:07:34Z","timestamp":1441980454000},"page":"450-462","source":"Crossref","is-referenced-by-count":17,"title":["The cerebral isthmus: fiber tract anatomy, functional significance, and surgical considerations"],"prefix":"10.3171","volume":"124","author":[{"given":"Christos","family":"Koutsarnakis","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Athens, Evangelismos Hospital;"},{"name":"Microneurosurgery Laboratory, Evangelismos Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Faidon","family":"Liakos","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Athens, Evangelismos Hospital;"},{"name":"Microneurosurgery Laboratory, Evangelismos Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Evangelia","family":"Liouta","sequence":"additional","affiliation":[{"name":"Hellenic Center for Neurosurgical Research \u201cPetros Kokkalis;\u201d and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Konstantinos","family":"Themistoklis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Athens, Evangelismos Hospital;"},{"name":"Microneurosurgery Laboratory, Evangelismos Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Damianos","family":"Sakas","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Athens, Evangelismos Hospital;"},{"name":"Hellenic Center for Neurosurgical Research \u201cPetros Kokkalis;\u201d and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George","family":"Stranjalis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Athens, Evangelismos Hospital;"},{"name":"Hellenic Center for Neurosurgical Research \u201cPetros Kokkalis;\u201d and"},{"name":"Microneurosurgery Laboratory, Evangelismos Hospital, Athens, Greece"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-jns142680","series-title":"Neurosurg Rev","doi-asserted-by":"publisher","first-page":"192","DOI":"10.1007\/s10143-002-0239-4","article-title":"Transcortical or transcallosal approach to ventricle-associated lesions: a clinical study on the prognostic role of surgical approach","volume":"26","author":"Asgari","year":"2003"},{"key":"b2-jns142680","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"960","DOI":"10.1007\/s00381-006-0131-6","article-title":"Transsylvian functional hemispherectomy","volume":"22","author":"Binder","year":"2006"},{"key":"b3-jns142680","series-title":"Neuroimage","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1006\/nimg.2002.1136","article-title":"Virtual in vivo interactive dissection of white matter fasciculi in the human brain","volume":"17","author":"Catani","year":"2002"},{"key":"b4-jns142680","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"8","DOI":"10.1002\/ana.20319","article-title":"Perisylvian language networks of the human brain","volume":"57","author":"Catani","year":"2005"},{"key":"b5-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"463","DOI":"10.3171\/2010.9.JNS10530","article-title":"Central core of the cerebrum","volume":"114","author":"Choi","year":"2011"},{"key":"b6-jns142680","series-title":"Philos Trans R Soc Lond B Biol Sci","doi-asserted-by":"publisher","first-page":"1271","DOI":"10.1098\/rstb.2005.1661","article-title":"What is the function of the claustrum?","volume":"360","author":"Crick","year":"2005"},{"issue":"1 Suppl","key":"b7-jns142680","series-title":"Neurosurgery","first-page":"36","article-title":"Lateral ventricle tumors: surgical strategies according to tumor origin and development\u2014a series of 72 cases","volume":"56","author":"D\u2019Angelo","year":"2005"},{"key":"b8-jns142680","series-title":"Hum Brain Mapp","doi-asserted-by":"publisher","first-page":"1790","DOI":"10.1002\/hbm.22292","article-title":"Development of insula connectivity between ages 12 and 30 revealed by high angular resolution diffusion imaging","volume":"35","author":"Dennis","year":"2014"},{"key":"b9-jns142680","series-title":"J Neurooncol","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1007\/s11060-005-9109-6","article-title":"New concepts in surgery of WHO grade II gliomas: functional brain mapping, connectionism and plasticity\u2014a review","volume":"79","author":"Duffau","year":"2006"},{"key":"b10-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1097\/00006123-200010000-00001","article-title":"The insular lobe: physiopathological and surgical considerations","volume":"47","author":"Duffau","year":"2000"},{"key":"b11-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"461","DOI":"10.3171\/JNS\/2008\/109\/9\/0461","article-title":"Intraoperative subcortical stimulation mapping of language pathways in a consecutive series of 115 patients with Grade II glioma in the left dominant hemisphere","volume":"109","author":"Duffau","year":"2008"},{"key":"b12-jns142680","series-title":"Brain","doi-asserted-by":"publisher","first-page":"797","DOI":"10.1093\/brain\/awh423","article-title":"New insights into the anatomofunctional connectivity of the semantic system: a study using cortico-subcortical electrostimulations","volume":"128","author":"Duffau","year":"2005"},{"key":"b13-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"431","DOI":"10.3171\/jns.2004.100.3.0431","article-title":"Surgical removal of corpus callosum infiltrated by low-grade glioma: functional outcome and oncological considerations","volume":"100","author":"Duffau","year":"2004"},{"key":"b14-jns142680","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"29","DOI":"10.1007\/BF01401969","article-title":"Neurosurgical topography of the optic radiation in the temporal lobe","volume":"92","author":"Ebeling","year":"1988"},{"key":"b15-jns142680","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"143","DOI":"10.1007\/BF01406373","article-title":"Topography of the uncinate fascicle and adjacent temporal fiber tracts","volume":"115","author":"Ebeling","year":"1992"},{"issue":"6","key":"b16-jns142680","series-title":"Neurosurg Focus","first-page":"E2","article-title":"Transcortical surgery for lateral ventricular tumors","volume":"10","author":"Ellenbogen","year":"2001"},{"key":"b17-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"430","DOI":"10.1227\/NEU.0b013e3182592faa","article-title":"High-definition fiber tractography of the human brain: neuroanatomical validation and neurosurgical applications","volume":"71","author":"Fernandez-Miranda","year":"2012"},{"issue":"6 Suppl 3","key":"b18-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"989","DOI":"10.1227\/01.NEU.0000297076.98175.67","article-title":"Three-dimensional microsurgical and tractographic anatomy of the white matter of the human brain","volume":"62","author":"Fern\u00e1ndez-Miranda","year":"2008"},{"key":"b19-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"764","DOI":"10.3171\/JNS\/2008\/108\/4\/0764","article-title":"The claustrum and its projection system in the human brain: a microsurgical and tractographic anatomical study","volume":"108","author":"Fern\u00e1ndez-Miranda","year":"2008"},{"key":"b20-jns142680","series-title":"Neuropsychopharmacology","doi-asserted-by":"publisher","first-page":"2384","DOI":"10.1038\/sj.npp.1301165","article-title":"Three-year outcomes in deep brain stimulation for highly resistant obsessive-compulsive disorder","volume":"31","author":"Greenberg","year":"2006"},{"key":"b21-jns142680","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1136\/jnnp.42.2.134","article-title":"Functional consequences of the transcallosal removal of intraventricular tumours","volume":"42","author":"Jeeves","year":"1979"},{"key":"b22-jns142680","series-title":"Annu Rev Neurosci","doi-asserted-by":"publisher","first-page":"75","DOI":"10.1146\/annurev.neuro.051508.135735","article-title":"Using diffusion imaging to study human connectional anatomy","volume":"32","author":"Johansen-Berg","year":"2009"},{"issue":"2","key":"b23-jns142680","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E2","DOI":"10.3171\/2009.5.FOCUS0997","article-title":"Embryological development of the human insula and its implications for the spread and resection of insular gliomas","volume":"27","author":"Kalani","year":"2009"},{"issue":"2 Suppl Operative","key":"b24-jns142680","series-title":"Neurosurgery","first-page":"290","article-title":"Delineation of the safe zone in surgery of sylvian insular triangle: morphometric analysis and magnetic resonance imaging study","volume":"70","author":"Kaneko","year":"2012"},{"key":"b25-jns142680","series-title":"AJNR Am J Neuroradiol","first-page":"677","article-title":"MR imaging of the temporal stem: anatomic dissection tractography of the uncinate fasciculus, inferior occipitofrontal fasciculus, and Meyer\u2019s loop of the optic radiation","volume":"25","author":"Kier","year":"2004"},{"key":"b26-jns142680","series-title":"Schweiz Arch Neurol Psychiatr","first-page":"247","article-title":"Erleichterung der makroskopischen Pr\u00e4paration des Gehirns durch den Gefrierproze\u00df","volume":"36","author":"Klingler","year":"1935"},{"key":"b27-jns142680","series-title":"J Psychiatr Res","doi-asserted-by":"publisher","first-page":"26","DOI":"10.1016\/j.jpsychires.2014.03.006","article-title":"Diffusion tensor imaging (DTI) studies in patients with obsessive-compulsive disorder (OCD): a review","volume":"54","author":"Koch","year":"2014"},{"issue":"Suppl 2","key":"b28-jns142680","series-title":"Neurosurgery","first-page":"305","article-title":"Microsurgical anatomy of the white matter tracts in hemispherotomy","volume":"10","author":"Kucukyuruk","year":"2014"},{"key":"b29-jns142680","series-title":"J Magn Reson Imaging","doi-asserted-by":"publisher","first-page":"478","DOI":"10.1002\/jmri.20683","article-title":"Artifacts and pitfalls in diffusion MRI","volume":"24","author":"Le Bihan","year":"2006"},{"key":"b30-jns142680","series-title":"Biol Psychiatry","doi-asserted-by":"publisher","first-page":"908","DOI":"10.1016\/j.biopsych.2013.04.010","article-title":"Impaired anatomical connectivity and related executive functions: differentiating vulnerability and disease marker in bipolar disorder","volume":"74","author":"Linke","year":"2013"},{"key":"b31-jns142680","series-title":"Atlas Cerebri Humani","author":"Ludwig","year":"1956"},{"key":"b32-jns142680","series-title":"Clin Neurophysiol","doi-asserted-by":"publisher","first-page":"1941","DOI":"10.1016\/j.clinph.2009.05.030","article-title":"Functional topography of the ventral striatum and anterior limb of the internal capsule determined by electrical stimulation of awake patients","volume":"120","author":"Machado","year":"2009"},{"key":"b33-jns142680","series-title":"Brain Struct Funct","doi-asserted-by":"publisher","first-page":"343","DOI":"10.1007\/s00429-008-0199-8","article-title":"The extreme capsule in humans and rethinking of the language circuitry","volume":"213","author":"Makris","year":"2009"},{"key":"b34-jns142680","series-title":"J Neurooncol","doi-asserted-by":"publisher","first-page":"179","DOI":"10.1007\/s11060-005-9084-y","article-title":"Extension of paralimbic low grade gliomas: toward an anatomical classification based on white matter invasion patterns","volume":"78","author":"Mandonnet","year":"2006"},{"issue":"3 Suppl Operative","key":"b35-jns142680","series-title":"Neurosurgery","first-page":"4","article-title":"New insights into the anatomic dissection of the temporal stem with special emphasis on the inferior fronto-occipital fasciculus: implications in surgical approach to left mesiotemporal and temporoinsular structures","volume":"66","author":"Martino","year":"2010"},{"key":"b36-jns142680","series-title":"Brain Cogn","doi-asserted-by":"publisher","first-page":"525","DOI":"10.1016\/j.bandc.2004.03.005","article-title":"The interhemispheric transcallosal-transversal approach to the lesions of the anterior and middle third ventricle: surgical validity and neuropsychological evaluation of the outcome","volume":"55","author":"Mazza","year":"2004"},{"key":"b37-jns142680","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"90","DOI":"10.1001\/archneur.1963.00460070100010","article-title":"Effects of different brain lesions on card sorting: The role of the frontal lobes","volume":"9","author":"Milner","year":"1963"},{"key":"b38-jns142680","series-title":"Behav Neurosci","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1037\/a0014723","article-title":"Effects on executive function following damage to the prefrontal cortex in the rhesus monkey (Macaca mulatta)","volume":"123","author":"Moore","year":"2009"},{"key":"b39-jns142680","series-title":"The Human Central Nervous System","author":"Nieuwenhuys","year":"2008"},{"key":"b40-jns142680","series-title":"Brain","doi-asserted-by":"publisher","first-page":"3781","DOI":"10.1093\/brain\/aws276","article-title":"Interhemispheric temporal lobe connectivity predicts language impairment in adolescents born preterm","volume":"135","author":"Northam","year":"2012"},{"key":"b41-jns142680","series-title":"J Neurol","doi-asserted-by":"publisher","first-page":"1860","DOI":"10.1007\/s00415-012-6421-x","article-title":"Functional consequences of a section of the anterior part of the body of the corpus callosum: evidence from an interhemispheric transcallosal approach","volume":"259","author":"Peltier","year":"2012"},{"key":"b42-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"294","DOI":"10.3171\/jns.2006.105.2.294","article-title":"Optic radiations: a microsurgical anatomical study","volume":"105","author":"Peltier","year":"2006"},{"key":"b43-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"512","DOI":"10.3171\/2009.6.JNS081712","article-title":"Microsurgical anatomy of the ventral callosal radiations: new destination, correlations with diffusion tensor imaging fiber-tracking, and clinical relevance","volume":"112","author":"Peltier","year":"2010"},{"key":"b44-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"1033","DOI":"10.3171\/2009.6.JNS08132","article-title":"Microsurgical anatomy of the temporal stem: clinical relevance and correlations with diffusion tensor imaging fiber tracking","volume":"112","author":"Peltier","year":"2010"},{"key":"b45-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1174","DOI":"10.1227\/01.NEU.0000140843.62311.24","article-title":"Anatomy of the anterior temporal lobe and the frontotemporal region demonstrated by fiber dissection","volume":"55","author":"Peuskens","year":"2004"},{"key":"b46-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"824","DOI":"10.1227\/NEU.0b013e318236760d","article-title":"Transsylvian-transinsular approaches to the insula and basal ganglia: operative techniques and results with vascular lesions","volume":"70","author":"Potts","year":"2012"},{"issue":"4 Suppl","key":"b47-jns142680","series-title":"Neurosurgery","first-page":"S1","article-title":"The cerebrum","volume":"51","author":"Rhoton","year":"2002"},{"issue":"4 Suppl","key":"b48-jns142680","series-title":"Neurosurgery","first-page":"S207","article-title":"The lateral and third ventricles","volume":"51","author":"Rhoton","year":"2002"},{"issue":"2","key":"b49-jns142680","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E2","DOI":"10.3171\/2009.11.FOCUS09245","article-title":"The cerebral sulci and gyri","volume":"28","author":"Ribas","year":"2010"},{"key":"b50-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"739","DOI":"10.3171\/jns.2004.101.5.0739","article-title":"White matter fiber dissection of the optic radiations of the temporal lobe and implications for surgical approaches to the temporal horn","volume":"101","author":"Sincoff","year":"2004"},{"key":"b51-jns142680","series-title":"Neuropsychologia","doi-asserted-by":"publisher","first-page":"4155","DOI":"10.1016\/j.neuropsychologia.2010.10.023","article-title":"Fiber tracking functionally distinct components of the internal capsule","volume":"48","author":"Sullivan","year":"2010"},{"key":"b52-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"891","DOI":"10.3171\/jns.2004.100.5.0891","article-title":"Microsurgical anatomy of the insula and the sylvian fissure","volume":"100","author":"Tanriover","year":"2004"},{"key":"b53-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"685","DOI":"10.1227\/00006123-198611000-00001","article-title":"Microsurgical anatomy and operative approaches to the lateral ventricles","volume":"19","author":"Timurkaynak","year":"1986"},{"key":"b54-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"720","DOI":"10.3171\/jns.1999.90.4.0720","article-title":"Topographic anatomy of the insular region","volume":"90","author":"T\u00fcre","year":"1999"},{"key":"b55-jns142680","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"417","DOI":"10.1097\/00006123-200008000-00028","article-title":"Fiber dissection technique: lateral aspect of the brain","volume":"47","author":"T\u00fcre","year":"2000"},{"key":"b56-jns142680","series-title":"Front Syst Neurosci","first-page":"1","article-title":"The neural architecture of the language comprehension network: converging evidence from lesion and connectivity analyses","volume":"5","author":"Turken","year":"2011"},{"key":"b57-jns142680","series-title":"Brain","doi-asserted-by":"publisher","first-page":"1692","DOI":"10.1093\/brain\/awt094","article-title":"Dissecting the uncinate fasciculus: disorders, controversies and a hypothesis","volume":"136","author":"Von Der Heide","year":"2013"},{"key":"b58-jns142680","series-title":"Radiology","doi-asserted-by":"publisher","first-page":"77","DOI":"10.1148\/radiol.2301021640","article-title":"Fiber tract-based atlas of human white matter anatomy","volume":"230","author":"Wakana","year":"2004"},{"key":"b59-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"775","DOI":"10.3171\/JNS\/2008\/108\/4\/0775","article-title":"Diffusion tensor tractography of the temporal stem on the inferior limiting sulcus","volume":"108","author":"Wang","year":"2008"},{"key":"b60-jns142680","series-title":"Acta Neurochir Suppl (Wien)","first-page":"122","article-title":"The Z\u00fcrich amygdalohippocampectomy series: a short up-date","volume":"50","author":"Wieser","year":"1990"},{"key":"b61-jns142680","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"445","DOI":"10.1016\/S0090-3019(82)80016-5","article-title":"Selective amygdalohippocampectomy as a surgical treatment of mesiobasal limbic epilepsy","volume":"17","author":"Wieser","year":"1982"},{"key":"b62-jns142680","series-title":"Microneurosurgery","volume":"I","author":"Ya\u015fargil","year":"1984"},{"key":"b63-jns142680","series-title":"Microneurosurgery","volume":"IVA","author":"Ya\u015fargil","year":"1994"},{"key":"b64-jns142680","series-title":"Microneurosurgery","volume":"IVB","author":"Ya\u015fargil","year":"1995"},{"key":"b65-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"168","DOI":"10.3171\/2008.12.JNS081112","article-title":"The selective amygdalohippocampectomy for intractable temporal limbic seizures","volume":"112","author":"Ya\u015fargil","year":"2010"},{"key":"b66-jns142680","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1007\/BF01540867","article-title":"Tumours of the limbic and paralimbic system","volume":"116","author":"Ya\u015fargil","year":"1992"},{"key":"b67-jns142680","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"725","DOI":"10.3171\/jns.2004.101.5.0725","article-title":"Impact of temporal lobe surgery","volume":"101","author":"Yasargil","year":"2004"},{"issue":"6B","key":"b68-jns142680","series-title":"Neurosurg Focus","first-page":"E1","article-title":"Surgical anatomy of supratentorial midline lesions","volume":"18","author":"Ya\u015fargil","year":"2005"},{"key":"b69-jns142680","series-title":"Neurosurg Clin N Am","doi-asserted-by":"publisher","first-page":"243","DOI":"10.1016\/S1042-3680(18)30591-6","article-title":"Surgery and results of selective amygdala-hippocampectomy in one hundred patients with nonlesional limbic epilepsy","volume":"4","author":"Ya\u015fargil","year":"1993"},{"key":"b70-jns142680","series-title":"Neuropsychopharmacology","doi-asserted-by":"publisher","first-page":"959","DOI":"10.1038\/npp.2011.279","article-title":"Quantitative tract-specific measures of uncinate and cingulum in major depression using diffusion tensor imaging","volume":"37","author":"Zhang","year":"2012"},{"key":"b71-jns142680","series-title":"Brain Res","doi-asserted-by":"publisher","first-page":"223","DOI":"10.1016\/j.brainres.2010.10.104","article-title":"Altered white matter integrity in first-episode, treatment-naive young adults with major depressive disorder: a tract-based spatial statistics study","volume":"1369","author":"Zhu","year":"2011"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/124\/2\/article-p450.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/124\/2\/article-p450.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/124\/2\/article-p450.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2024,3,9]],"date-time":"2024-03-09T09:58:55Z","timestamp":1709978335000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/124\/2\/article-p450.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":71,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/2015.3.jns142680","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2016,2]]}}}