{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,9]],"date-time":"2026-01-09T00:28:53Z","timestamp":1767918533877,"version":"3.49.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2016,5]]},"abstract":"<jats:p>The object of this study was to analyze the pathology of collateral vessels newly induced by indirect bypass surgery for moyamoya disease (MMD). An autopsy analysis was conducted on a 39-year-old woman with MMD who had died of a brainstem infarction. The patient had undergone bilateral indirect bypass surgeries 22 years earlier. Sufficient revascularization via bilateral external carotid arterial systems was confirmed by cerebral angiography before her death. Macroscopic observation of the operative areas revealed countless meandering vessels on the internal surface of the dura mater connected with small vessels on the brain surface and in the subpial brain tissue. Notably, microscopic analysis of these vessels revealed the characteristic 3-layer structure of an arterial wall. This autopsy analysis was the first to confirm that indirect bypass surgery had induced the formation of a new arterial network (arteriogenesis) and that this network had been maintained for more than 20 years to compensate for the chronic cerebral ischemia caused by the MMD.<\/jats:p>","DOI":"10.3171\/2015.4.jns15155","type":"journal-article","created":{"date-parts":[[2015,9,25]],"date-time":"2015-09-25T09:59:26Z","timestamp":1443175166000},"page":"1211-1214","source":"Crossref","is-referenced-by-count":14,"title":["First autopsy analysis of a neovascularized arterial network induced by indirect bypass surgery for moyamoya disease: case report"],"prefix":"10.3171","volume":"124","author":[{"given":"Maki","family":"Mukawa","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Nariai","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Motoki","family":"Inaji","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Natsumi","family":"Tamada","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Taketoshi","family":"Maehara","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Yoshiharu","family":"Matsushima","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kikuo","family":"Ohno","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Mariko","family":"Negi","sequence":"additional","affiliation":[{"name":"Human Pathology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Daisuke","family":"Kobayashi","sequence":"additional","affiliation":[{"name":"Human Pathology, Tokyo Medical and Dental University, Bunkyo-ku, Tokyo, Japan"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-jns15155","series-title":"Cerebrovasc Dis","doi-asserted-by":"publisher","first-page":"305","DOI":"10.1159\/000343225","article-title":"Clinical features, surgical treatment and long-term outcome in adult patients with Moyamoya disease in China","volume":"34","author":"Bao","year":"2012"},{"key":"b2-jns15155","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"34","DOI":"10.1227\/NEU.0b013e3181fc5ec2","article-title":"Clinical and angiographic outcomes from indirect revascularization surgery for Moyamoya disease in adults and children: a review of 63 procedures","volume":"68","author":"Dusick"},{"key":"b3-jns15155","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"94","DOI":"10.3171\/2012.4.JNS111103","article-title":"Indirect revascularization for nonmoyamoya intracranial arterial stenoses: clinical and angiographic outcomes","volume":"117","author":"Dusick","year":"2012"},{"issue":"Suppl","key":"b4-jns15155","series-title":"Neuropathology","doi-asserted-by":"publisher","first-page":"S61","DOI":"10.1046\/j.1440-1789.2000.00300.x","article-title":"Moyamoya disease","volume":"20","author":"Fukui","year":"2000"},{"key":"b5-jns15155","series-title":"J Cell Mol Med","doi-asserted-by":"publisher","first-page":"45","DOI":"10.1111\/j.1582-4934.2006.tb00290.x","article-title":"Arteriogenesis versus angiogenesis: similarities and differences","volume":"10","author":"Heil","year":"2006"},{"issue":"Suppl 2","key":"b6-jns15155","series-title":"Clin Neurol Neurosurg","doi-asserted-by":"publisher","first-page":"S203","DOI":"10.1016\/S0303-8467(97)00044-9","article-title":"Histopathological studies on spontaneous occlusion of the circle of Willis (cerebrovascu-lar moyamoya disease)","volume":"99","author":"Hosoda","year":"1997"},{"key":"b7-jns15155","series-title":"Childs Nerv Syst","first-page":"734","article-title":"How does angiogenesis develop in pediatric moyamoya disease after surgery? 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