{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:25:00Z","timestamp":1794324300000,"version":"4.9.0"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2016,2]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECT<\/jats:title>\n                    <jats:p>Anterior cervical corpectomy with fusion has become the most widely used procedure for the treatment of multilevel cervical stenosis. Although an autologous bone graft is the gold standard for vertebral replacement after corpectomy, industrial implants have become popular because they result in no donor-site morbidity. In this study, the authors compared clinical and radiological results of autologous iliac grafts versus those of bone-filled polyetherketoneketone (PEKK) cage implants.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The clinical and radiological data of 46 patients with degenerative multilevel cervical stenosis and who underwent 1- or 2-level anterior median corpectomy between 2004 and 2012 were analyzed. The patients in Group 1 were treated with vertebral replacement with an autologous iliac graft, and those in Group 2 were treated with a PEKK cage implant. Each patient also underwent osteosynthesis with an anterior plate-screw system. Visual analog scale (VAS) and European Myelopathy Scale scores, loss of height and regional cervical lordosis angle, and complication rates of the 2 groups were compared.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>The mean follow-up time was 20 months. In both groups, the VAS and European Myelopathy Scale scores improved significantly. The loss of height was 3.7% in patients with iliac grafts and 5.3% in patients with PEKK implants. The rates of osseous fusion were similar in Groups 1 and 2 (94.7% and 91.3%, respectively). At the end of the follow-up period, none of the patients complained about donor-site pain. One patient in Group 1 suffered a fracture of the iliac bone that required osteosynthesis. Four patients in Group 2 had to receive revision surgery for cage and\/or plate-screw dislocation and new neurological deficit or intractable pain.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Preoperative pain and radicularand myelopathic symptoms improve after decompression irrespective of the material used for vertebral replacement. The use of PEKK cages for vertebral replacement seems to result in a higher risk of implant-related complications. A prospective randomized study is necessary to supply evidence for the use of autografts and artificial implants after anterior cervical corpectomy with fusion.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2015.5.spine14887","type":"journal-article","created":{"date-parts":[[2015,10,13]],"date-time":"2015-10-13T19:52:41Z","timestamp":1444765961000},"page":"309-314","source":"Crossref","is-referenced-by-count":13,"title":["Autologous bone graft versus PEKK cage for vertebral replacement after 1- or 2-level anterior median corpectomy"],"prefix":"10.3171","volume":"24","author":[{"given":"Stefan","family":"Koehler","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University Hospital Wuerzburg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Furat","family":"Raslan","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Klinikum Hohe Warte, Bayreuth, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Stetter","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Wuerzburg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stefan Mark","family":"Rueckriegel","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Wuerzburg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ralf-Ingo","family":"Ernestus","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Wuerzburg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Westermaier","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University Hospital Wuerzburg; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-spine14887","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1055","DOI":"10.1097\/00007632-199505000-00012","article-title":"Iliac crest bone graft harvest donor site morbidity. A statistical evaluation","volume":"20","author":"Banwart","year":"1995"},{"issue":"4 Suppl 2","key":"b2-spine14887","series-title":"Neurosurgery","first-page":"295","article-title":"Cervical corpectomy: complications and outcomes","volume":"63","author":"Boakye","year":"2008"},{"key":"b3-spine14887","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"236","DOI":"10.1097\/00007632-198803000-00003","article-title":"Cervical stabilization by plate and bone fusion","volume":"13","author":"Brown","year":"1988"},{"key":"b4-spine14887","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"517","DOI":"10.1016\/j.jocn.2011.06.029","article-title":"Corpectomy with titanium cage reconstruction in the cervical spine","volume":"19","author":"Castellvi","year":"2012"},{"key":"b5-spine14887","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1402","DOI":"10.1097\/01.brs.0000166526.78058.3c","article-title":"Early failures following cervical corpectomy reconstruction with titanium mesh cages and anterior plating","volume":"30","author":"Daubs","year":"2005"},{"key":"b6-spine14887","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"E109","DOI":"10.1097\/BRS.0b013e318221b5af","article-title":"Evaluation of treatment effectiveness for the herniated cervical disc: a systematic review","volume":"37","author":"Gebremariam","year":"2012"},{"key":"b7-spine14887","series-title":"J Korean Neurosurg Soc","doi-asserted-by":"publisher","first-page":"135","DOI":"10.3340\/jkns.2012.51.3.135","article-title":"Radiographic comparison of four anterior fusion methods in two level cervical disc diseases: autograft plate fixation versus cage plate fixation versus stand-alone cage fusion versus corpectomy and plate fixation","volume":"51","author":"Kim","year":"2012"},{"key":"b8-spine14887","series-title":"J Korean Neurosurg Soc","doi-asserted-by":"publisher","first-page":"189","DOI":"10.3340\/jkns.2013.54.3.189","article-title":"Anterior cervical discectomy and fusion using a stand-alone polyetheretherketone cage packed with local autobone: assessment of bone fusion and subsidence","volume":"54","author":"Park","year":"2013"},{"key":"b9-spine14887","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"965","DOI":"10.1007\/s00586-004-0826-x","article-title":"Experimental study of the participation of the vertebral endplate in the integration of bone grafts","volume":"14","author":"Porto Filho","year":"2005"},{"key":"b10-spine14887","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"255","DOI":"10.3171\/jns.1998.88.2.0255","article-title":"A comparative analysis of fusion rates and donor-site morbidity for autogeneic rib and iliac crest bone grafts in posterior cervical fusions","volume":"88","author":"Sawin","year":"1998"},{"key":"b11-spine14887","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"134","DOI":"10.1097\/00007632-200301150-00008","article-title":"Donor site morbidity after anterior iliac crest bone harvest for single-level anterior cervical discectomy and fusion","volume":"28","author":"Silber","year":"2003"},{"key":"b12-spine14887","series-title":"J Bone Joint Surg Am","first-page":"607","article-title":"The treatment of certain cervicalspine disorders by anterior removal of the intervertebral disc and interbody fusion","volume":"40-A","author":"Smith","year":"1958"},{"key":"b13-spine14887","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1007\/BF01358747","article-title":"Anterior cervical allograft arthrodesis and instrumentation: multilevel interbody grafting or strut graft reconstruction","volume":"6","author":"Swank","year":"1997"},{"key":"b14-spine14887","series-title":"Eur Spine J","doi-asserted-by":"publisher","first-page":"654","DOI":"10.1007\/s00586-009-0897-9","article-title":"Comparison between anterior cervical discectomy fusion and cervical corpectomy fusion using titanium cages for reconstruction: analysis of outcome and long-term follow-up","volume":"18","author":"Uribe","year":"2009"},{"key":"b15-spine14887","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"801","DOI":"10.1007\/s00701-013-1655-7","article-title":"Expandable titanium cages for anterior column cervical reconstruction and their effect on sagittal profile: a review of 48 cases","volume":"155","author":"Waschke","year":"2013"},{"key":"b16-spine14887","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"1736","DOI":"10.1097\/01.brs.0000172158.31437.ce","article-title":"Distractable vertebral cages for reconstruction after cervical corpectomy","volume":"30","author":"Woiciechowsky","year":"2005"}],"container-title":["Journal of Neurosurgery: Spine"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/24\/2\/article-p309.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/24\/2\/article-p309.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-spine\/24\/2\/article-p309.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T17:54:11Z","timestamp":1681581251000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-spine\/24\/2\/article-p309.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2016,2]]},"references-count":16,"journal-issue":{"issue":"2"},"URL":"https:\/\/doi.org\/10.3171\/2015.5.spine14887","relation":{},"ISSN":["1547-5654"],"issn-type":[{"value":"1547-5654","type":"print"}],"subject":[],"published":{"date-parts":[[2016,2]]}}}