{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T02:12:26Z","timestamp":1790820746077,"version":"4.1.0"},"reference-count":34,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2015,9]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECT<\/jats:title>\n                    <jats:p>Carpal tunnel syndrome causes increased cross-sectional area (CSA) of the median nerve, which can be assessed by high-definition ultrasonography. It is unclear today, however, whether high-definition ultrasonography may play a role in the postoperative period. This prospective study aimed to determine the natural history of the morphology of the median nerve at the carpal tunnel after surgical decompression assessed by high-definition ultrasonography.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>Between October and December 2014, patients with suspected carpal tunnel syndrome who were referred to the authors\u2019 center for peripheral neurosurgery were prospectively enrolled and underwent pre- and postoperative (3 months) high-definition ultrasonography, electrophysiology, and clinical testing.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>\n                      Eighty-one patients were enrolled in the study, and 100% were clinically better at the 3-month follow-up. The mean CSA decreased from 14.7 \u00b1 4.9 mm\n                      <jats:sup>2<\/jats:sup>\n                      to 12.4 \u00b1 3.4 mm\n                      <jats:sup>2<\/jats:sup>\n                      (mean \u00b1 SD, p &lt; 0.0001). The mean distal motor latency decreased from 6.6 \u00b1 2.4 msec to 4.8 \u00b1 1.0 msec (mean \u00b1 SD, p &lt; 0.0001). Ninety-eight percent of patients who were available for electrodiagnostic follow-up showed an improvement of the distal motor latency; only 80% had a reduction in the CSA.\n                    <\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The authors present the second-largest series of patients with sonographic follow-up after surgical decompression of the carpal tunnel reported in the literature so far. This study, which showed a decrease in size of the median nerve after surgical decompression, suggests that the preoperative increase in median nerve CSA at the carpal tunnel may be due to compression and that enlargement of the median nerve is (partially) reversible.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2015.6.focus15216","type":"journal-article","created":{"date-parts":[[2015,9,1]],"date-time":"2015-09-01T03:41:33Z","timestamp":1441078893000},"page":"E6","source":"Crossref","is-referenced-by-count":23,"title":["Sonographic short-term follow-up after surgical decompression of the median nerve at the carpal tunnel: a single-center prospective observational study"],"prefix":"10.3171","volume":"39","author":[{"given":"Sueleyman","family":"Tas","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Frank","family":"Staub","sequence":"additional","affiliation":[{"name":"Center for Peripheral Neurosurgery, Dossenheim-Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Thomas","family":"Dombert","sequence":"additional","affiliation":[{"name":"Center for Peripheral Neurosurgery, Dossenheim-Heidelberg, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Gerhard","family":"Marquardt","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christian","family":"Senft","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Seifert","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephan","family":"Duetzmann","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Frankfurt; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-focus15216","series-title":"Clin Radiol","first-page":"891","article-title":"Ultrasound evaluation of patients with carpal tunnel syndrome before and after endoscopic release of the transverse carpal ligament","volume":"62","author":"Abicalaf","year":"2007"},{"key":"b2-focus15216","series-title":"Skeletal Radiol","first-page":"121","article-title":"High-frequency ultrasound examination of the wrist and hand","volume":"28","author":"Bianchi","year":"1999"},{"key":"b3-focus15216","series-title":"Eur J Ultrasound","first-page":"29","article-title":"Ultrasound of the hand","volume":"14","author":"Bianchi","year":"2001"},{"key":"b4-focus15216","series-title":"J Neurosurg","first-page":"709","article-title":"Preoperative ultrasound-guided mapping of peripheral nerves","volume":"119","author":"Gofeld","year":"2013"},{"key":"b5-focus15216","series-title":"J Radiol","first-page":"1869","article-title":"Ultrasound of peripheral nerves","volume":"86","author":"Martinoli","year":"2005"},{"key":"b6-focus15216","series-title":"Clin Neurophysiol","first-page":"2064","article-title":"Carpal tunnel syndrome: ultrasound, neurophysiology, clinical and patient-oriented assessment","volume":"119","author":"Padua","year":"2008"},{"key":"b7-focus15216","series-title":"High-Resolution Sonography of the Peripheral Nervous System","author":"Peer","year":"2008"},{"key":"b8-focus15216","series-title":"J Bone Joint Surg Am","first-page":"1600","article-title":"Pathophysiology of nerve compression syndromes: response of peripheral nerves to loading","volume":"81","author":"Rempel","year":"1999"},{"key":"b9-focus15216","series-title":"Muscle Nerve","article-title":"Quantitative ultrasound of denervated hand muscles","author":"Simon","year":"2014"},{"key":"b10-focus15216","series-title":"Clin Neurophysiol","first-page":"391","article-title":"A comparison of ultrasonographic and electrophysiologic \u2018inching\u2019 in ulnar neuropathy at the elbow","volume":"126","author":"Simon","year":"2015"},{"key":"b11-focus15216","series-title":"Muscle Nerve","first-page":"987","article-title":"Carpal tunnel syndrome: clinical and sonographic follow-up after surgery","volume":"38","author":"Smidt","year":"2008"},{"key":"b12-focus15216","series-title":"J Clin Endocrinol Metab","first-page":"905","article-title":"Ultrasound measurement of median and ulnar nerve cross-sectional area in acromegaly","volume":"93","author":"Tagliafico","year":"2008"},{"key":"b13-focus15216","series-title":"J Neurol Neurosurg Psychiatry","first-page":"63","article-title":"High-resolution sonography versus EMG in the diagnosis of carpal tunnel 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