{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,1]],"date-time":"2026-07-01T06:21:43Z","timestamp":1782886903734,"version":"3.54.5"},"reference-count":13,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2016,1]]},"abstract":"<jats:p>Triple spinal dysraphism is extremely rare. There are published reports of multiple discrete neural tube defects with intervening normal segments that are explained by the multisite closure theory of primary neurulation, having an association with Chiari malformation Type II consistent with the unified theory of McLone. The authors report on a 1-year-old child with contiguous myelomeningocele and lipomyelomeningocele centered on Type I split cord malformation with Chiari malformation Type II and hydrocephalus. This composite anomaly is probably due to select abnormalities of the neurenteric canal during gastrulation, with a contiguous cascading impact on both dysjunction of the neural tube and closure of the neuropore, resulting in a small posterior fossa, probably bringing the unified theory of McLone closer to the unified theory of Pang.<\/jats:p>","DOI":"10.3171\/2015.6.peds15179","type":"journal-article","created":{"date-parts":[[2015,10,16]],"date-time":"2015-10-16T16:07:26Z","timestamp":1445011646000},"page":"103-106","source":"Crossref","is-referenced-by-count":14,"title":["Contiguous triple spinal dysraphism associated with Chiari malformation Type II and hydrocephalus: an embryological conundrum between the unified theory of Pang and the unified theory of McLone"],"prefix":"10.3171","volume":"17","author":[{"given":"Sivashanmugam","family":"Dhandapani","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Anirudh","family":"Srinivasan","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-peds15179","series-title":"Neurotoxicol Teratol","doi-asserted-by":"publisher","first-page":"515","DOI":"10.1016\/j.ntt.2004.12.007","article-title":"Human neural tube defects: developmental biology, epidemiology, and genetics","volume":"27","author":"Detrait","year":"2005"},{"key":"b2-peds15179","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"411","DOI":"10.3171\/2013.7.PEDS13221","article-title":"\u201cHorseshoe cord terminus\u201d sans filum around a bone spur: a rare composite of faulty gastrulation with agenesis of secondary neurulation: case report\u201d","volume":"12","author":"Dhandapani","year":"2013"},{"key":"b3-peds15179","series-title":"Neurol India","doi-asserted-by":"publisher","first-page":"708","DOI":"10.4103\/0028-3886.149450","article-title":"The triad of holocord syringomyelia, Chiari malformation and tethered cord: amelioration with simple detethering\u2014a case for revisiting traction hypothesis?","volume":"62","author":"Kapoor","year":"2014"},{"key":"b4-peds15179","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"609","DOI":"10.1007\/s00381-012-1976-5","article-title":"Multiple neural tube defects may not be very rare","volume":"29","author":"Mahalik","year":"2013"},{"key":"b5-peds15179","series-title":"Pediatr Neurosci","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1159\/000120432","article-title":"The cause of Chiari II malformation: a unified theory","volume":"15","author":"McLone","year":"1989"},{"key":"b6-peds15179","series-title":"Concepts in Pediatric Neurosurgery","first-page":"170","article-title":"Lipomeningoceles of the conus medullaris","author":"McLone","year":"1983"},{"key":"b7-peds15179","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"451","DOI":"10.1227\/00006123-199209000-00010","article-title":"Split cord malformation: Part I: A unified theory of embryogenesis for double spinal cord malformations","volume":"31","author":"Pang","year":"1992"},{"key":"b8-peds15179","series-title":"J Neuroradiol","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1016\/S0150-9861(04)96875-7","article-title":"Spinal dysraphism: MR imaging rationale","volume":"31","author":"Rossi","year":"2004"},{"key":"b9-peds15179","series-title":"Surg Neurol Int","doi-asserted-by":"publisher","first-page":"147","DOI":"10.4103\/2152-7806.104741","article-title":"Multiple neural tube defects in a child: A rare developmental anomaly","volume":"3","author":"Singh","year":"2012"},{"key":"b10-peds15179","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"376","DOI":"10.1007\/s00381-003-0728-y","article-title":"Multiple coexistent dysraphic pathologies","volume":"19","author":"Solanki","year":"2003"},{"key":"b11-peds15179","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"160","DOI":"10.3171\/PED\/2008\/1\/2\/160","article-title":"Triple neural tube defect and the multisite closure theory for neural tube defects: is there an additional site? 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