{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:25:45Z","timestamp":1794324345291,"version":"4.9.0"},"reference-count":16,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>In this single-center series, the authors retrospectively evaluated the effectiveness, safety, and midterm follow-up results of ruptured aneurysms treated by implantation of a flow diverter device (FDD).<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>The records of 17 patients (12 females, 5 males, average World Federation of Neurosurgical Societies score = 2.9) who presented with subarachnoid hemorrhage (SAH) due to the rupture of an intracranial aneurysm treated with an FDD were retrospectively reviewed. Of 17 ruptured aneurysms, 8 were blood blister\u2013like aneurysms and the remaining 9 were dissecting aneurysms. The mean delay between SAH and treatment was 4.2 days. Intraprocedural and periprocedural morbidity and mortality were recorded. Clinical and angiographic follow-up evaluations were conducted between 6 and 12 months after the procedure.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>None of the ruptured aneurysms re-bled after endovascular treatment. The overall mortality rate was 12% (2\/17), involving 2 patients who died after a few days because of complications of SAH. The overall morbidity rate was 12%: 1 patient experienced intraparenchymal bleeding during the repositioning of external ventricular drainage, and 1 patient with a posterior inferior cerebellar artery aneurysm developed paraplegia due to a spinal cord infarction after 2 weeks. The angiographic follow-up evaluations showed a complete occlusion of the aneurysm in 12 of 15 surviving patients; of the 3 remaining cases, 1 patient showed a remnant of the aneurysm, 1 patient was retreated due to an enlargement of the aneurysm, and 1 patient was lost at the angiographic follow-up.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>FDDs can be used in patients with ruptured aneurysms, where conventional neurosurgical or endovascular treatments can be challenging.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2016.11.jns161937","type":"journal-article","created":{"date-parts":[[2017,4,7]],"date-time":"2017-04-07T10:03:49Z","timestamp":1491559429000},"page":"1037-1043","source":"Crossref","is-referenced-by-count":68,"title":["Flow diverter devices in ruptured intracranial aneurysms: a single-center experience"],"prefix":"10.3171","volume":"128","author":[{"given":"Emilio","family":"Lozupone","sequence":"first","affiliation":[{"name":"Department of Neuroradiology, ASST Grande Ospedale Metropolitano Niguarda, Milan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mariangela","family":"Piano","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, ASST Grande Ospedale Metropolitano Niguarda, Milan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Valvassori","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, ASST Grande Ospedale Metropolitano Niguarda, Milan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luca","family":"Quilici","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, ASST Grande Ospedale Metropolitano Niguarda, Milan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guglielmo","family":"Pero","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, ASST Grande Ospedale Metropolitano Niguarda, Milan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Emiliano","family":"Visconti","sequence":"additional","affiliation":[{"name":"Department of Radiology, Policlinico Universitario \u201cAgostino Gemelli,\u201d Rome, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Edoardo","family":"Boccardi","sequence":"additional","affiliation":[{"name":"Department of Neuroradiology, ASST Grande Ospedale Metropolitano Niguarda, Milan; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns161937","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"419","DOI":"10.3171\/jns.1998.89.3.0419","article-title":"Blood blister-like aneurysms of the internal carotid artery","volume":"89","author":"Abe M,","year":"1998","unstructured":"Abe M, Tabuchi K, Yokoyama H, Uchino A: Blood blister-like aneurysms of the internal carotid artery. J Neurosurg 89:419\u2013424, 199810.3171\/jns.1998.89.3.0419"},{"key":"b2-jns161937","series-title":"Cardiovasc Intervent Radiol","doi-asserted-by":"publisher","first-page":"30","DOI":"10.1007\/s00270-011-0204-0","article-title":"Antiplatelet and anticoagulant drugs in interventional radiology","volume":"35","author":"Altenburg A,","year":"2012","unstructured":"Altenburg A, Haage P: Antiplatelet and anticoagulant drugs in interventional radiology. Cardiovasc Intervent Radiol 35:30\u201342, 20122169850510.1007\/s00270-011-0204-0"},{"key":"b3-jns161937","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"202","DOI":"10.1136\/neurintsurg-2013-011090","article-title":"Treatment of ruptured blood blister-like aneurysms with flow diverter SILK stents","volume":"7","author":"Aydin K,","year":"2015","unstructured":"Aydin K, Arat A, Sencer S, Hakyemez B, Barburoglu M, Sencer A, : Treatment of ruptured blood blister-like aneurysms with flow diverter SILK stents. J Neurointerv Surg 7:202\u2013209, 20152449127110.1136\/neurintsurg-2013-011090"},{"key":"b4-jns161937","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"e4","DOI":"10.1136\/jnis.2010.004572","article-title":"Treatment of two blood blister-like aneurysms with flow diverter stenting","volume":"4","author":"Consoli A,","year":"2012","unstructured":"Consoli A, Nappini S, Renieri L, Limbucci N, Ricciardi F, Mangiafico S: Treatment of two blood blister-like aneurysms with flow diverter stenting. J Neurointerv Surg 4:e4, 20122199046210.1136\/jnis.2010.004572"},{"key":"b5-jns161937","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"1276","DOI":"10.1016\/j.jocn.2007.08.023","article-title":"Primary treatment of a blood-blister-like aneurysm of the internal carotid artery with Guglielmi detachable coil embolisation","volume":"15","author":"Doorenbosch X,","year":"2008","unstructured":"Doorenbosch X, Harding M: Primary treatment of a blood-blister-like aneurysm of the internal carotid artery with Guglielmi detachable coil embolisation. J Clin Neurosci 15:1276\u20131279, 200810.1016\/j.jocn.2007.08.02318842411"},{"key":"b6-jns161937","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"56","DOI":"10.1136\/jnis.2009.000083","article-title":"Curative cerebrovascular reconstruction with the Pipeline embolization device: the emergence of definitive endovascular therapy for intracranial aneurysms","volume":"1","author":"Fiorella D,","year":"2009","unstructured":"Fiorella D, Lylyk P, Szikora I, Kelly ME, Albuquerque FC, McDougall CG, : Curative cerebrovascular reconstruction with the Pipeline embolization device: the emergence of definitive endovascular therapy for intracranial aneurysms. J Neurointerv Surg 1:56\u201365, 200910.1136\/jnis.2009.00008321994109"},{"key":"b7-jns161937","series-title":"AJNR Am J Neuroradiol","doi-asserted-by":"publisher","first-page":"1132","DOI":"10.3174\/ajnr.A2016","article-title":"The efficacy of endovascular stenting in the treatment of supraclinoid internal carotid artery blister aneurysms using a stent-in-stent technique","volume":"31","author":"Gaughen JR Jr,","year":"2010","unstructured":"Gaughen JR Jr, Hasan D, Dumont AS, Jensen ME, McKenzie J, Evans AJ: The efficacy of endovascular stenting in the treatment of supraclinoid internal carotid artery blister aneurysms using a stent-in-stent technique. AJNR Am J Neuroradiol 31:1132\u20131138, 201010.3174\/ajnr.A201620150303"},{"key":"b8-jns161937","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"2346","DOI":"10.1161\/STROKEAHA.106.479576","article-title":"A new endoluminal, flow-disrupting device for treatment of saccular aneurysms","volume":"38","author":"Kallmes DF,","year":"2007","unstructured":"Kallmes DF, Ding YH, Dai D, Kadirvel R, Lewis DA, Cloft HJ: A new endoluminal, flow-disrupting device for treatment of saccular aneurysms. Stroke 38:2346\u20132352, 20071761536610.1161\/STROKEAHA.106.479576"},{"key":"b9-jns161937","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"480","DOI":"10.1227\/NEU.0000000000000005","article-title":"Reconstructive treatment of ruptured blood blister-like aneurysms with stent and coil","volume":"73","author":"Lim YC,","year":"2013","unstructured":"Lim YC, Kim BM, Suh SH, Jeon P, Kim SH, Ihn YK, : Reconstructive treatment of ruptured blood blister-like aneurysms with stent and coil. Neurosurgery 73:480\u2013488, 201310.1227\/NEU.000000000000000523728453"},{"key":"b10-jns161937","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"808","DOI":"10.1136\/neurintsurg-2014-011320","article-title":"Utilization of Pipeline embolization device for treatment of ruptured intracranial aneurysms: US multicenter experience","volume":"7","author":"Lin N,","year":"2015","unstructured":"Lin N, Brouillard AM, Keigher KM, Lopes DK, Binning MJ, Liebman KM, : Utilization of Pipeline embolization device for treatment of ruptured intracranial aneurysms: US multicenter experience. J Neurointerv Surg 7:808\u2013815, 20152523083910.1136\/neurintsurg-2014-011320"},{"key":"b11-jns161937","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"632","DOI":"10.1227\/01.NEU.0000339109.98070.65","article-title":"Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience","volume":"64","author":"Lylyk P,","year":"2009","unstructured":"Lylyk P, Miranda C, Ceratto R, Ferrario A, Scrivano E, Luna HR, : Curative endovascular reconstruction of cerebral aneurysms with the pipeline embolization device: the Buenos Aires experience. Neurosurgery 64:632\u2013643, N6, 200910.1227\/01.NEU.0000339109.98070.65"},{"key":"b12-jns161937","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"937","DOI":"10.3171\/2013.5.JNS122494","article-title":"Risk of hemorrhagic complication associated with ventriculoperitoneal shunt placement in aneurysmal subarachnoid hemorrhage patients on dual antiplatelet therapy","volume":"119","author":"Mahaney KB,","year":"2013","unstructured":"Mahaney KB, Chalouhi N, Viljoen S, Smietana J, Kung DK, Jabbour P, : Risk of hemorrhagic complication associated with ventriculoperitoneal shunt placement in aneurysmal subarachnoid hemorrhage patients on dual antiplatelet therapy. J Neurosurg 119:937\u2013942, 20132380853710.3171\/2013.5.JNS122494"},{"key":"b13-jns161937","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"662","DOI":"10.3171\/JNS\/2008\/108\/4\/0662","article-title":"Blood blister-like aneurysms of the internal carotid artery trunk causing subarachnoid hemorrhage: treatment and outcome","volume":"108","author":"Meling TR,","year":"2008","unstructured":"Meling TR, Sorteberg A, Bakke SJ, Sletteb\u00f8 H, Hernesniemi J, Sorteberg W: Blood blister-like aneurysms of the internal carotid artery trunk causing subarachnoid hemorrhage: treatment and outcome. J Neurosurg 108:662\u2013671, 200810.3171\/JNS\/2008\/108\/4\/066218377243"},{"key":"b14-jns161937","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"812","DOI":"10.3171\/jns.2007.106.5.812","article-title":"Endovascular treatment of blood blister-like aneurysms of the internal carotid artery","volume":"106","author":"Park JH,","year":"2007","unstructured":"Park JH, Park IS, Han DH, Kim SH, Oh CW, Kim JE, : Endovascular treatment of blood blister-like aneurysms of the internal carotid artery. J Neurosurg 106:812\u2013819, 20071754252410.3171\/jns.2007.106.5.812"},{"key":"b15-jns161937","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"408","DOI":"10.3171\/2012.10.JNS112222","article-title":"Midterm and long-term follow-up of cerebral aneurysms treated with flow diverter devices: a single-center experience","volume":"118","author":"Piano M,","year":"2013","unstructured":"Piano M, Valvassori L, Quilici L, Pero G, Boccardi E: Midterm and long-term follow-up of cerebral aneurysms treated with flow diverter devices: a single-center experience. J Neurosurg 118:408\u2013416, 201310.3171\/2012.10.JNS11222223176329"},{"key":"b16-jns161937","series-title":"AJNR Am J Neuroradiol","doi-asserted-by":"publisher","first-page":"1139","DOI":"10.3174\/ajnr.A2023","article-title":"Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device","volume":"31","author":"Szikora I,","year":"2010","unstructured":"Szikora I, Berentei Z, Kulcsar Z, Marosfoi M, Vajda ZS, Lee W, : Treatment of intracranial aneurysms by functional reconstruction of the parent artery: the Budapest experience with the pipeline embolization device. AJNR Am J Neuroradiol 31:1139\u20131147, 201010.3174\/ajnr.A202320150304"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/128\/4\/article-p1037.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/128\/4\/article-p1037.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/128\/4\/article-p1037.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T01:14:31Z","timestamp":1743383671000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/128\/4\/article-p1037.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,4]]},"references-count":16,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2016.11.jns161937","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,4]]}}}