{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,1,13]],"date-time":"2026-01-13T13:44:45Z","timestamp":1768311885962,"version":"3.49.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,3]]},"abstract":"<jats:p>Improvement of visual field defects after surgical treatment for occipital lobe epilepsy is rare. Here, the authors report on a 24-year-old man with a 15-year history of refractory epilepsy that developed after he had undergone an occipital craniotomy to remove a cerebellar astrocytoma at the age of 4. His seizures started with an elementary visual aura, followed by secondary generalized tonic-clonic convulsion. Perimetry revealed left-sided incomplete hemianopia, and MRI showed an old contusion in the right occipital lobe. After evaluation with ictal video-electroencephalography, electrocorticography, and mapping of the visual cortex with subdural electrodes, the patient underwent resection of the scarred tissue, including the epileptic focus at the occipital lobe. After surgery, he became seizure free and his visual field defect improved gradually. In addition, postoperative <jats:sup>123<\/jats:sup>I-iomazenil (IMZ) SPECT showed partly normalized IMZ uptake in the visual cortex. This case is a practical example suggesting that neurological deficits attributable to the functional deficit zone can be remedied by successful focal resection.<\/jats:p>","DOI":"10.3171\/2016.12.jns161820","type":"journal-article","created":{"date-parts":[[2017,5,19]],"date-time":"2017-05-19T13:59:29Z","timestamp":1495202369000},"page":"862-866","source":"Crossref","is-referenced-by-count":3,"title":["Improvement of visual field defects after focal resection for occipital lobe epilepsy: case report"],"prefix":"10.3171","volume":"128","author":[{"given":"Takahiro","family":"Yamamoto","sequence":"first","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Tadashi","family":"Hamasaki","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hideo","family":"Nakamura","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kazumichi","family":"Yamada","sequence":"additional","affiliation":[],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"60","DOI":"10.1002\/ana.410440112","article-title":"Surgical outcome in occipital lobe epilepsy: implications for pathophysiology","volume":"44","author":"Aykut-Bingol C","year":"1998","unstructured":"Aykut-Bingol C, Bronen RA, Kim JH, Spencer DD, Spencer SS: Surgical outcome in occipital lobe epilepsy: implications for pathophysiology. Ann Neurol 44:60\u201369, 1998966759310.1002\/ana.410440112"},{"key":"b2","series-title":"Glia","doi-asserted-by":"publisher","first-page":"1203","DOI":"10.1002\/glia.22317","article-title":"Aquaporin-4 and epilepsy","volume":"60","author":"Binder DK","year":"2012","unstructured":"Binder DK, Nagelhus EA, Ottersen OP: Aquaporin-4 and epilepsy. Glia 60:1203\u20131214, 20122237846710.1002\/glia.22317"},{"key":"b3","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"57","DOI":"10.3171\/JNS\/2008\/109\/7\/0057","article-title":"Surgical treatment of occipital lobe epilepsy","volume":"109","author":"Binder DK","year":"2008","unstructured":"Binder DK, Von Lehe M, Kral T, Bien CG, Urbach H, Schramm J, : Surgical treatment of occipital lobe epilepsy. J Neurosurg 109:57\u201369, 20081859043310.3171\/JNS\/2008\/109\/7\/0057"},{"key":"b4","series-title":"Brain","doi-asserted-by":"publisher","first-page":"1209","DOI":"10.1093\/brain\/awh458","article-title":"Occipital epilepsy: lateral versus mesial","volume":"128","author":"Blume WT","year":"2005","unstructured":"Blume WT, Wiebe S, Tapsell LM: Occipital epilepsy: lateral versus mesial. Brain 128:1209\u20131225, 200510.1093\/brain\/awh45815788545"},{"key":"b5","series-title":"Brain","doi-asserted-by":"publisher","first-page":"2320","DOI":"10.1093\/brain\/awf236","article-title":"Lateralizing semiology predicts the seizure outcome after epilepsy surgery in the posterior cortex","volume":"125","author":"Boesebeck F","year":"2002","unstructured":"Boesebeck F, Schulz R, May T, Ebner A: Lateralizing semiology predicts the seizure outcome after epilepsy surgery in the posterior cortex. Brain 125:2320\u20132331, 20021224408810.1093\/brain\/awf236"},{"key":"b6","series-title":"Epilepsy Res","doi-asserted-by":"publisher","first-page":"1","DOI":"10.1016\/j.eplepsyres.2007.07.004","article-title":"Tailored resections in occipital lobe epilepsy surgery guided by monitoring with subdural electrodes: characteristics and outcome","volume":"77","author":"Caicoya AG","year":"2007","unstructured":"Caicoya AG, Macarr\u00f3n J, Alb\u00edsua J, Serratosa JM: Tailored resections in occipital lobe epilepsy surgery guided by monitoring with subdural electrodes: characteristics and outcome. Epilepsy Res 77:1\u201310, 200710.1016\/j.eplepsyres.2007.07.00417923392"},{"key":"b7","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"1442","DOI":"10.1111\/j.1528-1167.2005.70904.x","article-title":"Clinical features of patients with posterior cortex epilepsies and predictors of surgical outcome","volume":"46","author":"Dalmagro CL","year":"2005","unstructured":"Dalmagro CL, Bianchin MM, Velasco TR, Alexandre V Jr, Walz R, Terra-Bustamante VC, : Clinical features of patients with posterior cortex epilepsies and predictors of surgical outcome. Epilepsia 46:1442\u20131449, 20051614644010.1111\/j.1528-1167.2005.70904.x"},{"key":"b8","series-title":"Epilepsy Behav","doi-asserted-by":"publisher","first-page":"131","DOI":"10.1016\/j.yebeh.2016.01.001","article-title":"Interictal epileptiform discharge effects on neuropsychological assessment and epilepsy surgical planning","volume":"56","author":"Drane DL","year":"2016","unstructured":"Drane DL, Ojemann JG, Kim MS, Gross RE, Miller JW, Faught RE Jr, : Interictal epileptiform discharge effects on neuropsychological assessment and epilepsy surgical planning. Epilepsy Behav 56:131\u2013138, 201610.1016\/j.yebeh.2016.01.00126874864"},{"key":"b9","series-title":"Prog Neurobiol","doi-asserted-by":"publisher","first-page":"277","DOI":"10.1016\/0301-0082(79)90018-2","article-title":"Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters","volume":"13","author":"Hertz L","year":"1979","unstructured":"Hertz L: Functional interactions between neurons and astrocytes I. Turnover and metabolism of putative amino acid transmitters. Prog Neurobiol 13:277\u2013323, 197910.1016\/0301-0082(79)90018-242117"},{"key":"b10","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"2334","DOI":"10.1111\/j.1528-1167.2010.02673.x","article-title":"Intractable occipital lobe epilepsy: clinical characteristics and surgical treatment","volume":"51","author":"Jobst BC","year":"2010","unstructured":"Jobst BC, Williamson PD, Thadani VM, Gilbert KL, Holmes GL, Morse RP, : Intractable occipital lobe epilepsy: clinical characteristics and surgical treatment. Epilepsia 51:2334\u20132337, 201010.1111\/j.1528-1167.2010.02673.x20662891"},{"key":"b11","series-title":"Neuroscience","doi-asserted-by":"publisher","first-page":"1045","DOI":"10.1016\/j.neuroscience.2004.06.008","article-title":"Potassium buffering in the central nervous system","volume":"129","author":"Kofuji P","year":"2004","unstructured":"Kofuji P, Newman EA: Potassium buffering in the central nervous system. Neuroscience 129:1045\u20131056, 200410.1016\/j.neuroscience.2004.06.00815561419"},{"key":"b12","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"688","DOI":"10.1111\/j.1528-1167.2005.56604.x","article-title":"Occipital lobe epilepsy: clinical characteristics, surgical outcome, and role of diagnostic modalities","volume":"46","author":"Kun Lee S","year":"2005","unstructured":"Kun Lee S, Young Lee S, Kim DW, Soo Lee D, Chung CK: Occipital lobe epilepsy: clinical characteristics, surgical outcome, and role of diagnostic modalities. Epilepsia 46:688\u2013695, 200510.1111\/j.1528-1167.2005.56604.x"},{"key":"b13","series-title":"Textbook of Epilepsy Surgery","doi-asserted-by":"publisher","first-page":"779","DOI":"10.3109\/9780203091708-101","article-title":"The functional deficit zone","author":"L\u00fcders HO","year":"2008","unstructured":"L\u00fcders HO: The functional deficit zone, in L\u00fcders HO (ed): Textbook of Epilepsy Surgery. London: Informa Healthcare, 2008, pp 779\u201386810.3109\/9780203091708-101"},{"key":"b14","series-title":"Neuroscientist [epub ahead of print]","article-title":"Astroglial scarring and seizures: a cell biological perspective on epilepsy","author":"Robel S","year":"2016","unstructured":"Robel S: Astroglial scarring and seizures: a cell biological perspective on epilepsy. Neuroscientist [epub ahead of print], 2016"},{"key":"b15","series-title":"Brain","doi-asserted-by":"publisher","first-page":"1655","DOI":"10.1093\/brain\/115.6.1655","article-title":"Occipital lobe epilepsy: electroclinical manifestations, electrocorticography, cortical stimulation and outcome in 42 patients treated between 1930 and 1991. Surgery of occipital lobe epilepsy","volume":"115","author":"Salanova V","year":"1992","unstructured":"Salanova V, Andermann F, Olivier A, Rasmussen T, Quesney LF: Occipital lobe epilepsy: electroclinical manifestations, electrocorticography, cortical stimulation and outcome in 42 patients treated between 1930 and 1991. Surgery of occipital lobe epilepsy. Brain 115:1655\u20131680, 1992148645610.1093\/brain\/115.6.1655"},{"key":"b16","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"306","DOI":"10.3171\/2008.4.17490","article-title":"Occipital epilepsy: spatial categorization and surgical management","volume":"110","author":"Tandon N","year":"2009","unstructured":"Tandon N, Alexopoulos AV, Warbel A, Najm IM, Bingaman WE: Occipital epilepsy: spatial categorization and surgical management. J Neurosurg 110:306\u2013318, 20091904603810.3171\/2008.4.17490"},{"key":"b17","series-title":"Seizure","doi-asserted-by":"publisher","first-page":"608","DOI":"10.1016\/j.seizure.2007.04.009","article-title":"Correlation of MRI and histopathology in epileptogenic parietal and occipital lobe lesions","volume":"16","author":"Urbach H","year":"2007","unstructured":"Urbach H, Binder D, von Lehe M, Podlogar M, Bien CG, Becker A, : Correlation of MRI and histopathology in epileptogenic parietal and occipital lobe lesions. Seizure 16:608\u2013614, 20071756081010.1016\/j.seizure.2007.04.009"},{"key":"b18","series-title":"Epilepsy Res","doi-asserted-by":"publisher","first-page":"157","DOI":"10.1016\/j.eplepsyres.2011.08.004","article-title":"Versive seizures in occipital lobe epilepsy: lateralizing value and pathophysiology","volume":"97","author":"Usui N","year":"2011","unstructured":"Usui N, Mihara T, Baba K, Matsuda K, Tottori T, Umeoka S, : Versive seizures in occipital lobe epilepsy: lateralizing value and pathophysiology. Epilepsy Res 97:157\u2013161, 201110.1016\/j.eplepsyres.2011.08.00421885252"},{"key":"b19","series-title":"Prog Neurobiol","doi-asserted-by":"publisher","first-page":"188","DOI":"10.1016\/j.pneurobio.2015.09.003","article-title":"Translational potential of astrocytes in brain disorders","volume":"144","author":"Verkhratsky A","year":"2016","unstructured":"Verkhratsky A, Steardo L, Parpura V, Montana V: Translational potential of astrocytes in brain disorders. Prog Neurobiol 144:188\u2013205, 201610.1016\/j.pneurobio.2015.09.00326386136"},{"key":"b20","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"3","DOI":"10.1002\/ana.410310103","article-title":"Occipital lobe epilepsy: clinical characteristics, seizure spread patterns, and results of surgery","volume":"31","author":"Williamson PD","year":"1992","unstructured":"Williamson PD, Thadani VM, Darcey TM, Spencer DD, Spencer SS, Mattson RH: Occipital lobe epilepsy: clinical characteristics, seizure spread patterns, and results of surgery. Ann Neurol 31:3\u201313, 1992154334810.1002\/ana.410310103"},{"key":"b21","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"63","DOI":"10.1007\/s00701-014-2217-3","article-title":"Intractable occipital lobe epilepsy: clinical characteristics, surgical treatment, and a systematic review of the literature","volume":"157","author":"Yang PF","year":"2015","unstructured":"Yang PF, Jia YZ, Lin Q, Mei Z, Chen ZQ, Zheng ZY, : Intractable occipital lobe epilepsy: clinical characteristics, surgical treatment, and a systematic review of the literature. Acta Neurochir (Wien) 157:63\u201375, 201510.1007\/s00701-014-2217-3"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/128\/3\/article-p862.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/128\/3\/article-p862.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/128\/3\/article-p862.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,31]],"date-time":"2025-03-31T05:25:29Z","timestamp":1743398729000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/128\/3\/article-p862.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,3]]},"references-count":21,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2016.12.jns161820","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,3]]}}}