{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,17]],"date-time":"2026-05-17T09:27:38Z","timestamp":1779010058417,"version":"3.51.4"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,7]]},"abstract":"<jats:p>The authors describe the case of a 40-year-old man suffering from an epidural abscess in the thoracic spine due to a rarely isolated pathogen, <jats:italic>Streptobacillus moniliformis<\/jats:italic>, the causative agent of rat bite fever. Besides diffuse abdominal pain, ataxia, paresthesia, hypesthesia, and enhanced reflexes of the lower extremities, the patient suffered from a decreased sensation of bladder filling. His history was also positive for a rat bite 6 weeks earlier. Magnetic resonance imaging showed an epidural, space-occupying lesion compressing the spinal cord at the vertebral levels of T6\u20138. Neurosurgery revealed an epidural abscess, which was drained via laminectomy (T-7) and excision of the ligamentum flavum (T6\u20138). The etiological agent <jats:italic>S. moniliformis<\/jats:italic> was identified by 16S rRNA-based polymerase chain reaction and sequencing as well as by culture and mass spectrometry. Treatment with penicillin G led to complete resolution of the abscess and clinical recovery of the patient, who regained his bladder-filling sensation and free walking ability.<\/jats:p><jats:p>This case demonstrates that careful attention to the patient's history is essential in suspecting unusual bacterial pathogens as the cause of an epidural abscess and initiating the optimal diagnostic procedure and antimicrobial therapy.<\/jats:p>","DOI":"10.3171\/2016.12.spine161042","type":"journal-article","created":{"date-parts":[[2017,4,21]],"date-time":"2017-04-21T14:02:55Z","timestamp":1492783375000},"page":"92-96","source":"Crossref","is-referenced-by-count":11,"title":["A spinal epidural abscess due to Streptobacillus moniliformis infection following a rat bite: case report"],"prefix":"10.3171","volume":"27","author":[{"given":"Alexander","family":"Hammer","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, Paracelsus Medical University, N\u00fcrnberg;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dorit","family":"Wolff","sequence":"additional","affiliation":[{"name":"Mikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Friederich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Universit\u00e4tsklinikum Erlangen, Erlangen, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Walter","family":"Gei\u00dfd\u00f6rfer","sequence":"additional","affiliation":[{"name":"Mikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Friederich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Universit\u00e4tsklinikum Erlangen, Erlangen, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Michael","family":"Schrey","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Paracelsus Medical University, N\u00fcrnberg;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Renate","family":"Ziegler","sequence":"additional","affiliation":[{"name":"Institut f\u00fcr Klinikhygiene, Medizinische Mikrobiologie und Klinische Infektiologie, Universit\u00e4tsinstitut der Paracelsus Medizinischen Privatuniversit\u00e4t, N\u00fcrnberg, Germany"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hans-Herbert","family":"Steiner","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Paracelsus Medical University, N\u00fcrnberg;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Christian","family":"Bogdan","sequence":"additional","affiliation":[{"name":"Mikrobiologisches Institut-Klinische Mikrobiologie, Immunologie und Hygiene, Friederich-Alexander-Universit\u00e4t Erlangen-N\u00fcrnberg, Universit\u00e4tsklinikum Erlangen, Erlangen, Germany; and"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1-spine161042","series-title":"Clin Microbiol Rev","doi-asserted-by":"publisher","first-page":"231","DOI":"10.1128\/CMR.00041-10","article-title":"Microbiology of animal bite wound infections","volume":"24","author":"Abrahamian FM,","year":"2011","unstructured":"Abrahamian FM, Goldstein EJ: Microbiology of animal bite wound infections. 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