{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,5]],"date-time":"2026-09-05T06:34:52Z","timestamp":1788590092745,"version":"build-2803163510"},"reference-count":37,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["JNS"],"published-print":{"date-parts":[[2017,4]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Diffusion-weighted MRI was used to assess periprocedural lesion load after repair of unruptured intracranial aneurysms (UIA) by microsurgical clipping (MC) and endovascular coiling (EC).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>Patients with UIA were assigned to undergo MC or EC according to interdisciplinary consensus and underwent diffusion-weighted imaging (DWI) 1 day before and 1 day after aneurysm treatment. Newly detected lesions by DWI after treatment were the primary end point of this prospective study. Lesions detected by DWI were categorized as follows: A) 1\u20133 DWI spots &lt; 10 mm, B) &gt; 3 DWI spots &lt; 10 mm, C) single DWI lesion &gt; 10 mm, or D) DWI lesion related to surgical access.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>Between 2010 and 2014, 99 cases were included. Sixty-two UIA were treated by MC and 37 by EC. There were no significant differences between groups in age, sex, aneurysm size, occurrence of multiple aneurysms in 1 patient, or presence of lesions detected by DWI before treatment. Aneurysms treated by EC were significantly more often located in the posterior circulation (p &lt; 0.001). Diffusion-weighted MRI detected new lesions in 27 (43.5%) and 20 (54.1%) patients after MC and EC, respectively (not significant). The pattern of lesions detected by DWI varied significantly between groups (p &lt; 0.001). Microembolic lesions (A and B) found on DWI were detected more frequently after EC (A, 14 cases; B, 5 cases) than after MC (A, 5 cases), whereas C and D were rare after EC (C, 1 case) and occurred more often after MC (C, 12 cases and D, 10 cases). No procedure-related unfavorable outcomes were detected.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>According to the specific techniques, lesion patterns differ between MC and EC, whereas the frequency of new lesions found on DWI is similar after occlusion of UIA. In general, the lesion load was low in both groups, and lesions were clinically silent.<\/jats:p>\n<jats:p>Clinical trial registration no.: NCT01490463 (<jats:ext-link xmlns:xlink=\"http:\/\/www.w3.org\/1999\/xlink\" xlink:href=\"clinicaltrials.gov\" ext-link-type=\"uri\">clinicaltrials.gov<\/jats:ext-link>)<\/jats:p><\/jats:sec>","DOI":"10.3171\/2016.2.jns152456","type":"journal-article","created":{"date-parts":[[2016,5,21]],"date-time":"2016-05-21T23:01:04Z","timestamp":1463871664000},"page":"1070-1078","source":"Crossref","is-referenced-by-count":26,"title":["Early diffusion-weighted MRI lesions after treatment of unruptured intracranial aneurysms: a prospective study"],"prefix":"10.3171","volume":"126","author":[{"given":"Johannes","family":"Platz","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marlies","family":"Wagner","sequence":"additional","affiliation":[{"name":"Neuroradiology, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erdem","family":"G\u00fcresir","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Se-Jong","family":"You","sequence":"additional","affiliation":[{"name":"Neuroradiology, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Juergen","family":"Konczalla","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Richard du Mesnil","family":"de Rochemont","sequence":"additional","affiliation":[{"name":"Neuroradiology, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Joachim","family":"Berkefeld","sequence":"additional","affiliation":[{"name":"Neuroradiology, University Hospital Frankfurt, Goethe-University, Frankfurt, Germany"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Volker","family":"Seifert","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns152456","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"147","DOI":"10.1136\/jnis.2010.003616","article-title":"Thromboembolic events associated with endovascular treatment of cerebral aneurysms","volume":"3","author":"Altay T,","year":"2011","unstructured":"Altay T, Kang HI, Woo HH, Masaryk TJ, Rasmussen PA, Fiorella DJ, : Thromboembolic events associated with endovascular treatment of cerebral aneurysms. J Neurointerv Surg 3:147\u2013150, 201110.1136\/jnis.2010.00361621990807"},{"key":"b2-jns152456","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"1594","DOI":"10.1016\/S0140-6736(99)07083-X","article-title":"Silent embolism in diagnostic cerebral angiography and neurointerventional procedures: a prospective study","volume":"354","author":"Bendszus M,","year":"1999","unstructured":"Bendszus M, Koltzenburg M, Burger R, Warmuth-Metz M, Hofmann E, Solymosi L: Silent embolism in diagnostic cerebral angiography and neurointerventional procedures: a prospective study. Lancet 354:1594\u20131597, 199910.1016\/S0140-6736(99)07083-X10560674"},{"key":"b3-jns152456","series-title":"AJNR Am J Neuroradiol","first-page":"957","article-title":"Cerebral aneurysms treated by Guglielmi detachable coils: evaluation with diffusion-weighted MR imaging","volume":"21","author":"Biondi A,","year":"2000","unstructured":"Biondi A, Oppenheim C, Vivas E, Casasco A, Lalam T, Sourour N, : Cerebral aneurysms treated by Guglielmi detachable coils: evaluation with diffusion-weighted MR imaging. AJNR Am J Neuroradiol 21:957\u2013963, 200010815677"},{"key":"b4-jns152456","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"353","DOI":"10.1016\/S1474-4422(10)70057-0","article-title":"New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS)","volume":"9","author":"Bonati LH,","year":"2010","unstructured":"Bonati LH, Jongen LM, Haller S, Flach HZ, Dobson J, Nederkoorn PJ, : New ischaemic brain lesions on MRI after stenting or endarterectomy for symptomatic carotid stenosis: a substudy of the International Carotid Stenting Study (ICSS). Lancet Neurol 9:353\u2013362, 2010. (Erratum in Lancet Neurol 9: 345, 2010)10.1016\/S1474-4422(10)70057-0"},{"key":"b5-jns152456","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"703","DOI":"10.3171\/2009.6.JNS09483","article-title":"Endovascular coil occlusion of 152 middle cerebral artery aneurysms: initial and midterm angiographic and clinical results","volume":"112","author":"Bracard S,","year":"2010","unstructured":"Bracard S, Abdel-Kerim A, Thuillier L, Klein O, Anxionnat R, Finitsis S, : Endovascular coil occlusion of 152 middle cerebral artery aneurysms: initial and midterm angiographic and clinical results. J Neurosurg 112:703\u2013708, 20101985253610.3171\/2009.6.JNS09483"},{"key":"b6-jns152456","series-title":"J Korean Neurosurg Soc","doi-asserted-by":"publisher","first-page":"275","DOI":"10.3340\/jkns.2008.43.6.275","article-title":"Thromboembolic events after coil embolization of cerebral aneurysms: prospective study with diffusion-weighted magnetic resonance imaging follow-up","volume":"43","author":"Chung SW,","year":"2008","unstructured":"Chung SW, Baik SK, Kim Y, Park J: Thromboembolic events after coil embolization of cerebral aneurysms: prospective study with diffusion-weighted magnetic resonance imaging follow-up. J Korean Neurosurg Soc 43:275\u2013280, 20081909663210.3340\/jkns.2008.43.6.275"},{"key":"b7-jns152456","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"855","DOI":"10.1007\/s00234-005-1408-2","article-title":"Diffusion and perfusion MRI in patients with ruptured and unruptured intracranial aneurysms treated by endovascular coiling: complications, procedural results, MR findings and clinical outcome","volume":"47","author":"Cronqvist M,","year":"2005","unstructured":"Cronqvist M, Wirestam R, Ramgren B, Brandt L, Nilsson O, S\u00e4veland H, : Diffusion and perfusion MRI in patients with ruptured and unruptured intracranial aneurysms treated by endovascular coiling: complications, procedural results, MR findings and clinical outcome. Neuroradiology 47:855\u2013873, 200510.1007\/s00234-005-1408-216235046"},{"key":"b8-jns152456","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"837","DOI":"10.3171\/jns.2002.96.5.0837","article-title":"Postprocedure ischemic events after treatment of intracranial aneurysms with Guglielmi detachable coils","volume":"96","author":"Derdeyn CP,","year":"2002","unstructured":"Derdeyn CP, Cross DT III, Moran CJ, Brown GW, Pilgram TK, Diringer MN, : Postprocedure ischemic events after treatment of intracranial aneurysms with Guglielmi detachable coils. J Neurosurg 96:837\u2013843, 20021200869710.3171\/jns.2002.96.5.0837"},{"key":"b9-jns152456","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"322","DOI":"10.1016\/j.wneu.2012.12.011","article-title":"Middle cerebral artery aneurysms: a single-center series comparing endovascular and surgical treatment","volume":"81","author":"Diaz OM,","year":"2014","unstructured":"Diaz OM, Rangel-Castilla L, Barber S, Mayo RC, Klucznik R, Zhang YJ: Middle cerebral artery aneurysms: a single-center series comparing endovascular and surgical treatment. World Neurosurg 81:322\u2013329, 20142323810110.1016\/j.wneu.2012.12.011"},{"key":"b10-jns152456","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"864","DOI":"10.1136\/jnnp.2006.106823","article-title":"Treatment related morbidity of unruptured intracranial aneurysms: results of a prospective single centre series with an interdisciplinary approach over a 6 year period (1999\u20132005)","volume":"78","author":"Gerlach R,","year":"2007","unstructured":"Gerlach R, Beck J, Setzer M, Vatter H, Berkefeld J, Du Mesnil de Rochemont R, : Treatment related morbidity of unruptured intracranial aneurysms: results of a prospective single centre series with an interdisciplinary approach over a 6 year period (1999\u20132005). J Neurol Neurosurg Psychiatry 78:864\u2013871, 200710.1136\/jnnp.2006.106823"},{"key":"b11-jns152456","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"612","DOI":"10.1227\/01.NEU.0000204101.00996.D9","article-title":"Endovascular treatment of unruptured intracranial aneurysms: occurrence of thromboembolic events","volume":"58","author":"Grunwald IQ,","year":"2006","unstructured":"Grunwald IQ, Papanagiotou P, Politi M, Struffert T, Roth C, Reith W: Endovascular treatment of unruptured intracranial aneurysms: occurrence of thromboembolic events. Neurosurgery 58:612\u2013618, 20061657532410.1227\/01.NEU.0000204101.00996.D9"},{"key":"b12-jns152456","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"461","DOI":"10.1136\/neurintsurg-2013-010820","article-title":"Silent embolism after stent-assisted coiling of cerebral aneurysms: diffusion-weighted MRI study of 75 cases","volume":"6","author":"Hahnemann ML,","year":"2014","unstructured":"Hahnemann ML, Ringelstein A, Sandalcioglu IE, Goericke S, Moenninghoff C, Wanke I, : Silent embolism after stent-assisted coiling of cerebral aneurysms: diffusion-weighted MRI study of 75 cases. J Neurointerv Surg 6:461\u2013465, 201410.1136\/neurintsurg-2013-01082023929549"},{"key":"b13-jns152456","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"1101","DOI":"10.1007\/s00701-013-1706-0","article-title":"Predictors of thromboembolism during coil embolization in patients with unruptured intracranial aneurysm","volume":"155","author":"Jo KI,","year":"2013","unstructured":"Jo KI, Yeon JY, Kim KH, Jeon P, Kim JS, Hong SC: Predictors of thromboembolism during coil embolization in patients with unruptured intracranial aneurysm. Acta Neurochir (Wien) 155:1101\u20131106, 201310.1007\/s00701-013-1706-0"},{"key":"b14-jns152456","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"638","DOI":"10.1227\/NEU.0b013e3182846f74","article-title":"Cognitive outcome and clinically silent thromboembolic events after coiling of asymptomatic unruptured intracranial aneurysms","volume":"72","author":"Kang DH,","year":"2013","unstructured":"Kang DH, Hwang YH, Kim YS, Bae GY, Lee SJ: Cognitive outcome and clinically silent thromboembolic events after coiling of asymptomatic unruptured intracranial aneurysms. Neurosurgery 72:638\u2013645, 201310.1227\/NEU.0b013e3182846f7423277379"},{"key":"b15-jns152456","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"789","DOI":"10.1161\/STROKEAHA.112.669853","article-title":"MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms","volume":"44","author":"Kang DH,","year":"2013","unstructured":"Kang DH, Kim BM, Kim DJ, Suh SH, Kim DI, Kim YS, : MR-DWI-positive lesions and symptomatic ischemic complications after coiling of unruptured intracranial aneurysms. Stroke 44:789\u2013791, 20132320405210.1161\/STROKEAHA.112.669853"},{"key":"b16-jns152456","series-title":"J Clin Neurosci","doi-asserted-by":"publisher","first-page":"520","DOI":"10.1016\/j.jocn.2012.02.054","article-title":"Endovascular coiling of middle cerebral artery aneurysms as an alternative to surgical clipping","volume":"20","author":"Kim KH,","year":"2013","unstructured":"Kim KH, Cha KC, Kim JS, Hong SC: Endovascular coiling of middle cerebral artery aneurysms as an alternative to surgical clipping. J Clin Neurosci 20:520\u2013522, 201310.1016\/j.jocn.2012.02.05423375399"},{"key":"b17-jns152456","series-title":"J Korean Neurosurg Soc","doi-asserted-by":"publisher","first-page":"19","DOI":"10.3340\/jkns.2013.54.1.19","article-title":"Thromboembolic events associated with electrolytic detachment of Guglielmi detachable coils and target coils: comparison with use of diffusion-weighted MR imaging","volume":"54","author":"Kim MJ,","year":"2013","unstructured":"Kim MJ, Lim YC, Oh SY, Kim BM, Kim BS, Shin YS: Thromboembolic events associated with electrolytic detachment of Guglielmi detachable coils and target coils: comparison with use of diffusion-weighted MR imaging. J Korean Neurosurg Soc 54:19\u201324, 201310.3340\/jkns.2013.54.1.1924044075"},{"key":"b18-jns152456","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1161\/STROKEAHA.108.524777","article-title":"Symptomatic and silent ischemia associated with microsurgical clipping of intracranial aneurysms: evaluation with diffusion-weighted MRI","volume":"40","author":"Krayenb\u00fchl N,","year":"2009","unstructured":"Krayenb\u00fchl N, Erdem E, Oinas M, Krisht AF: Symptomatic and silent ischemia associated with microsurgical clipping of intracranial aneurysms: evaluation with diffusion-weighted MRI. Stroke 40:129\u2013133, 20091897437610.1161\/STROKEAHA.108.524777"},{"key":"b19-jns152456","series-title":"Clin Neurophysiol","doi-asserted-by":"publisher","first-page":"1878","DOI":"10.1016\/j.clinph.2011.02.007","article-title":"MRI-validation of SEP monitoring for ischemic events during microsurgical clipping of intracranial aneurysms","volume":"122","author":"Krayenb\u00fchl N,","year":"2011","unstructured":"Krayenb\u00fchl N, Sarnthein J, Oinas M, Erdem E, Krisht AF: MRI-validation of SEP monitoring for ischemic events during microsurgical clipping of intracranial aneurysms. Clin Neurophysiol 122:1878\u20131882, 20112137792410.1016\/j.clinph.2011.02.007"},{"key":"b20-jns152456","series-title":"J Neurol","doi-asserted-by":"publisher","first-page":"1304","DOI":"10.1007\/s00415-012-6795-9","article-title":"Interdisciplinary treatment of unruptured intracranial aneurysms: impact of intraprocedural rupture and ischemia in 563 aneurysms","volume":"260","author":"Kunz M,","year":"2013","unstructured":"Kunz M, Bakhshai Y, Zausinger S, Fesl G, Janssen H, Br\u00fcckmann H, : Interdisciplinary treatment of unruptured intracranial aneurysms: impact of intraprocedural rupture and ischemia in 563 aneurysms. J Neurol 260:1304\u20131313, 20132326359410.1007\/s00415-012-6795-9"},{"key":"b21-jns152456","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"366","DOI":"10.1136\/neurintsurg-2011-010225","article-title":"Heparin dosing is associated with diffusion weighted imaging lesion load following aneurysm coiling","volume":"5","author":"Lim Fat MJ,","year":"2013","unstructured":"Lim Fat MJ, Al-Hazzaa M, Bussi\u00e8re M, dos Santos MP, Lesiuk H, Lum C: Heparin dosing is associated with diffusion weighted imaging lesion load following aneurysm coiling. J Neurointerv Surg 5:366\u2013370, 201310.1136\/neurintsurg-2011-01022522641861"},{"key":"b22-jns152456","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"449","DOI":"10.1007\/s00234-013-1137-x","article-title":"Multiple antiplatelet therapy contributes to the reversible high signal spots on diffusion-weighted imaging in elective coiling of unruptured cerebral aneurysm","volume":"55","author":"Matsushige T,","year":"2013","unstructured":"Matsushige T, Kiura Y, Sakamoto S, Okazaki T, Shinagawa K, Ichinose N, : Multiple antiplatelet therapy contributes to the reversible high signal spots on diffusion-weighted imaging in elective coiling of unruptured cerebral aneurysm. Neuroradiology 55:449\u2013457, 201310.1007\/s00234-013-1137-x"},{"key":"b23-jns152456","series-title":"Turk Neurosurg","first-page":"772","article-title":"3.0-T diffusion images after clipping of middle cerebral artery aneurysm","volume":"23","author":"Murai Y,","year":"2013","unstructured":"Murai Y, Adachi K, Matano F, Takagi R, Amano Y, Kobayashi S, : 3.0-T diffusion images after clipping of middle cerebral artery aneurysm. Turk Neurosurg 23:772\u2013777, 201324310461"},{"key":"b24-jns152456","series-title":"Surg Neurol Int","doi-asserted-by":"publisher","first-page":"129","DOI":"10.4103\/2152-7806.119073","article-title":"Anatomical configuration of the Sylvian fissure and its influence on outcome after pterional approach for microsurgical aneurysm clipping","volume":"4","author":"Ngando HM,","year":"2013","unstructured":"Ngando HM, Maslehaty H, Schreiber L, Blaeser K, Scholz M, Petridis AK: Anatomical configuration of the Sylvian fissure and its influence on outcome after pterional approach for microsurgical aneurysm clipping. Surg Neurol Int 4:129, 201310.4103\/2152-7806.11907324231790"},{"key":"b25-jns152456","series-title":"J Neurosurg Anesthesiol","doi-asserted-by":"publisher","first-page":"100","DOI":"10.1097\/01.ana.0000163202.33236.mL","article-title":"Complications and postoperative care in patients undergoing treatment for unruptured intracranial aneurysms","volume":"17","author":"Niskanen M,","year":"2005","unstructured":"Niskanen M, Koivisto T, Rinne J, Ronkainen A, Pirskanen S, Saari T, : Complications and postoperative care in patients undergoing treatment for unruptured intracranial aneurysms. J Neurosurg Anesthesiol 17:100\u2013105, 200510.1097\/01.ana.0000163202.33236.mL15840997"},{"key":"b26-jns152456","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"1344","DOI":"10.1097\/00006123-200006000-00012","article-title":"Prevention and treatment of thromboembolic and ischemic complications associated with endovascular procedures: Part I\u2014Pathophysiological and pharmacological features","volume":"46","author":"Qureshi AI,","year":"2000","unstructured":"Qureshi AI, Luft AR, Sharma M, Guterman LR, Hopkins LN: Prevention and treatment of thromboembolic and ischemic complications associated with endovascular procedures: Part I\u2014Pathophysiological and pharmacological features. Neurosurgery 46:1344\u20131359, 200010.1097\/00006123-200006000-0001210834640"},{"key":"b27-jns152456","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"982","DOI":"10.3171\/jns.2005.103.6.0982","article-title":"Prospective evaluation of surgical microscope-integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery","volume":"103","author":"Raabe A,","year":"2005","unstructured":"Raabe A, Nakaji P, Beck J, Kim LJ, Hsu FP, Kamerman JD, : Prospective evaluation of surgical microscope-integrated intraoperative near-infrared indocyanine green videoangiography during aneurysm surgery. J Neurosurg 103:982\u2013989, 200510.3171\/jns.2005.103.6.098216381184"},{"key":"b28-jns152456","series-title":"Neurosurgery","doi-asserted-by":"publisher","first-page":"415","DOI":"10.1227\/NEU.0b013e3182804aa2","article-title":"Current management of middle cerebral artery aneurysms: surgical results with a \u201cclip first\u201d policy","volume":"72","author":"Rodr\u00edguez-Hern\u00e1ndez A,","year":"2013","unstructured":"Rodr\u00edguez-Hern\u00e1ndez A, Sughrue ME, Akhavan S, Habdank-Kolaczkowski J, Lawton MT: Current management of middle cerebral artery aneurysms: surgical results with a \u201cclip first\u201d policy. Neurosurgery 72:415\u2013427, 201310.1227\/NEU.0b013e3182804aa223208060"},{"key":"b29-jns152456","series-title":"AJNR Am J Neuroradiol","first-page":"5","article-title":"Silent thromboembolic events associated with the treatment of unruptured cerebral aneurysms by use of Guglielmi detachable coils: prospective study applying diffusion-weighted imaging","volume":"22","author":"Rordorf G,","year":"2001","unstructured":"Rordorf G, Bellon RJ, Budzik RE Jr, Farkas J, Reinking GF, Pergolizzi RS, : Silent thromboembolic events associated with the treatment of unruptured cerebral aneurysms by use of Guglielmi detachable coils: prospective study applying diffusion-weighted imaging. AJNR Am J Neuroradiol 22:5\u201310, 200111158880"},{"key":"b30-jns152456","series-title":"Neurosurgery","first-page":"22","article-title":"A clinical study of the parameters and effects of temporary arterial occlusion in the management of intracranial aneurysms","volume":"34","author":"Samson D,","year":"1994","unstructured":"Samson D, Batjer HH, Bowman G, Mootz L, Krippner WJ Jr, Meyer YJ, : A clinical study of the parameters and effects of temporary arterial occlusion in the management of intracranial aneurysms. Neurosurgery 34:22\u201329, 19948121566"},{"key":"b31-jns152456","series-title":"Neurointervention","doi-asserted-by":"publisher","first-page":"77","DOI":"10.5469\/neuroint.2012.7.2.77","article-title":"Silent microembolism on diffusion-weighted MRI after coil embolization of cerebral aneurysms","volume":"7","author":"Sim SY,","year":"2012","unstructured":"Sim SY, Shin YS: Silent microembolism on diffusion-weighted MRI after coil embolization of cerebral aneurysms. Neurointervention 7:77\u201384, 201210.5469\/neuroint.2012.7.2.7722970416"},{"key":"b32-jns152456","series-title":"AJNR Am J Neuroradiol","first-page":"2035","article-title":"Thromboembolic events associated with Guglielmi detachable coil embolization with use of diffusion-weighted MR imaging. Part II. Detection of the microemboli proximal to cerebral aneurysm","volume":"24","author":"Soeda A,","year":"2003","unstructured":"Soeda A, Sakai N, Murao K, Sakai H, Ihara K, Yamada N, : Thromboembolic events associated with Guglielmi detachable coil embolization with use of diffusion-weighted MR imaging. Part II. Detection of the microemboli proximal to cerebral aneurysm. AJNR Am J Neuroradiol 24:2035\u20132038, 200314625228"},{"key":"b33-jns152456","series-title":"AJNR Am J Neuroradiol","first-page":"127","article-title":"Thromboembolic events associated with Guglielmi detachable coil embolization of asymptomatic cerebral aneurysms: evaluation of 66 consecutive cases with use of diffusion-weighted MR imaging","volume":"24","author":"Soeda A,","year":"2003","unstructured":"Soeda A, Sakai N, Sakai H, Iihara K, Yamada N, Imakita S, : Thromboembolic events associated with Guglielmi detachable coil embolization of asymptomatic cerebral aneurysms: evaluation of 66 consecutive cases with use of diffusion-weighted MR imaging. AJNR Am J Neuroradiol 24:127\u2013132, 200312533341"},{"key":"b34-jns152456","series-title":"Clin Neurol Neurosurg","doi-asserted-by":"publisher","first-page":"129","DOI":"10.1016\/j.clineuro.2010.10.012","article-title":"Is the surgical repair of unruptured atherosclerotic aneurysms at a higher risk of intraoperative ischemia?","volume":"113","author":"Szel\u00e9nyi A,","year":"2011","unstructured":"Szel\u00e9nyi A, Beck J, Strametz R, Blasel S, Oszvald A, Raabe A, : Is the surgical repair of unruptured atherosclerotic aneurysms at a higher risk of intraoperative ischemia?. Clin Neurol Neurosurg 113:129\u2013135, 201110.1016\/j.clineuro.2010.10.012"},{"key":"b35-jns152456","series-title":"Lancet Neurol","doi-asserted-by":"publisher","first-page":"611","DOI":"10.1016\/S1474-4422(07)70170-9","article-title":"Silent brain infarcts: a systematic review","volume":"6","author":"Vermeer SE,","year":"2007","unstructured":"Vermeer SE, Longstreth WT Jr, Koudstaal PJ: Silent brain infarcts: a systematic review. Lancet Neurol 6:611\u2013619, 20071758236110.1016\/S1474-4422(07)70170-9"},{"key":"b36-jns152456","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"103","DOI":"10.1016\/S0140-6736(03)13860-3","article-title":"Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment","volume":"362","author":"Wiebers DO,","year":"2003","unstructured":"Wiebers DO, Whisnant JP, Huston J III, Meissner I, Brown RD Jr, Piepgras DG, : Unruptured intracranial aneurysms: natural history, clinical outcome, and risks of surgical and endovascular treatment. Lancet 362:103\u2013110, 200310.1016\/S0140-6736(03)13860-312867109"},{"key":"b37-jns152456","series-title":"J Neurointerv Surg","doi-asserted-by":"publisher","first-page":"24","DOI":"10.1136\/neurintsurg-2014-011478","article-title":"Coiling and clipping of middle cerebral artery aneurysms: a systematic review on clinical and imaging outcome","volume":"8","author":"Zijlstra IA,","year":"2016","unstructured":"Zijlstra IA, Verbaan D, Majoie CB, Vandertop P, van den Berg R: Coiling and clipping of middle cerebral artery aneurysms: a systematic review on clinical and imaging outcome. J Neurointerv Surg 8:24\u201329, 201610.1136\/neurintsurg-2014-01147825431306"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/126\/4\/article-p1070.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/126\/4\/article-p1070.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/126\/4\/article-p1070.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2025,3,23]],"date-time":"2025-03-23T03:12:45Z","timestamp":1742699565000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/126\/4\/article-p1070.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2017,4]]},"references-count":37,"journal-issue":{"issue":"4"},"URL":"https:\/\/doi.org\/10.3171\/2016.2.jns152456","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2017,4]]}}}