{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,11,10]],"date-time":"2026-11-10T15:24:43Z","timestamp":1794324283251,"version":"4.9.0"},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2016,10]]},"abstract":"\n OBJECTIVE<\/jats:title>\n In this single-center study the authors investigated the complications occurring before and after the introduction of the new Ascenda intrathecal catheter (Medtronic Inc.) in pediatric patients treated with intrathecal baclofen therapy (ITB) for spasticity and\/or dystonia.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n This was a retrospective review of 508 children who had received ITB, 416 with silicone catheters in the 13 years between September 1998 and September 2011 and 92 with Ascenda catheters in the 3 years between September 2011 and August 2014. The authors evaluated major complications such as infections, CSF leaks treated, and problems related to the catheter or pump, and they compared the 2 groups of patients who had received either a silicone catheter or an Ascenda catheter implant.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n One hundred twenty patients in the silicone group (29%) and 1 patient in the Ascenda group (1.1%; p < 0.001) had a major complication. In the silicone group 23 patients (5.5%) were affected by CSF leakage and 75 patients (18%) experienced 82 catheter-related events, such as occlusion, dislodgment, disconnection, or breakage, which required catheter replacement. In the Ascenda group, only 1 patient (1.1%) was affected by CSF leakage.<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n To the authors' knowledge, this study is the first in the literature to compare the performance of the new Ascenda catheter, introduced in 2011, with the traditional silicone catheter for intrathecal drug infusion. In their analysis, the authors found that the Ascenda catheter can reduce major complications related to the catheter after ITB pump implantation. Further investigation is necessary to expand on and confirm their results.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2016.4.peds15646","type":"journal-article","created":{"date-parts":[[2016,6,24]],"date-time":"2016-06-24T09:58:53Z","timestamp":1466762333000},"page":"493-498","source":"Crossref","is-referenced-by-count":35,"title":["Comparison between an Ascenda and a silicone catheter in intrathecal baclofen therapy in pediatric patients: analysis of complications"],"prefix":"10.3171","volume":"18","author":[{"given":"Francesco","family":"Motta","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Clara Eleonora","family":"Antonello","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"issue":"2","key":"b1-peds15646","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"e3","DOI":"10.3171\/foc.2006.21.2.4","article-title":"Intrathecal baclofen therapy in children","volume":"21","author":"Albright","year":"2006"},{"issue":"4 Suppl","key":"b2-peds15646","series-title":"J Neurosurg","first-page":"233","article-title":"Best-practice surgical techniques for intrathecal baclofen therapy","volume":"104","author":"Albright","year":"2006"},{"key":"b3-peds15646","series-title":"ISRN Neurol","first-page":"575168","article-title":"Complications of intrathecal baclofen pump: prevention and cure","volume":"2012","author":"Awaad","year":"2012"},{"key":"b4-peds15646","series-title":"Eur J Paediatr Neurol","doi-asserted-by":"publisher","first-page":"539","DOI":"10.1016\/j.ejpn.2011.05.003","article-title":"Effects of intrathecal baclofen on daily care in children with secondary generalized dystonia: a pilot study","volume":"15","author":"Bonouvri\u00e9","year":"2011"},{"key":"b5-peds15646","series-title":"J Pediatr Orthop","doi-asserted-by":"publisher","first-page":"76","DOI":"10.1097\/BPO.0b013e3181c6b257","article-title":"Complications of intrathecal baclofen pump therapy in pediatric patients","volume":"30","author":"Borowski","year":"2010"},{"key":"b6-peds15646","series-title":"Eur J Paediatr Neurol","doi-asserted-by":"publisher","first-page":"19","DOI":"10.1016\/j.ejpn.2009.05.002","article-title":"Consensus on the appropriate use of intrathecal baclofen (ITB) therapy in paediatric spasticity","volume":"14","author":"Dan","year":"2010"},{"key":"b7-peds15646","series-title":"PM R","doi-asserted-by":"publisher","first-page":"751","DOI":"10.1016\/j.pmrj.2010.01.016","article-title":"Incidence and identification of intrathecal baclofen catheter malfunction","volume":"2","author":"Dvorak","year":"2010"},{"key":"b8-peds15646","series-title":"J Anesth","doi-asserted-by":"publisher","first-page":"206","DOI":"10.1007\/s00540-013-1683-8","article-title":"Injection of intrathecal normal saline in decreasing postdural puncture headache","volume":"28","author":"Faridi Tazeh-Kand","year":"2014"},{"key":"b9-peds15646","series-title":"Childs Nerv Syst","doi-asserted-by":"publisher","first-page":"421","DOI":"10.1007\/s00381-010-1277-9","article-title":"Intrathecal baclofen therapy: complication avoidance and management","volume":"27","author":"Haranhalli","year":"2011"},{"key":"b10-peds15646","series-title":"Cochrane Database Syst Rev","first-page":"CD004552","article-title":"Intrathecal baclofen for treating spasticity in children with cerebral palsy","volume":"11","author":"Hasnat","year":"2015"},{"key":"b11-peds15646","series-title":"Acta Paediatr","doi-asserted-by":"publisher","first-page":"1337","DOI":"10.1111\/j.1651-2227.2010.01819.x","article-title":"The changing panorama of cerebral palsy in Sweden. 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