{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,17]],"date-time":"2026-10-17T16:10:08Z","timestamp":1792253408271,"version":"4.4.0"},"reference-count":42,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"6","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["SPI"],"published-print":{"date-parts":[[2016,12]]},"abstract":"<jats:p>Extracranial meningioma metastases (EMM) occur in 0.1% of intracranial meningioma patients and are more commonly seen in those with atypical and anaplastic histologies. While the lungs and pleura are the most common site of EMM, intraspinal and vertebral EMM also occur and are not well described in the literature. Although the presence of EMM can worsen prognosis, no standard of care has been established for EMM management.<\/jats:p>\n<jats:p>All patients treated for recurrent atypical\/anaplastic meningiomas between January 1985 and July 2014 at Memorial Sloan Kettering Cancer Center were screened for intraspinal and vertebral EMM. Of these patients, 2 were identified as having recurrent meningioma complicated by vertebral or intraspinal EMM. A review of the literature was also conducted. The PubMed database was screened for intraspinal and vertebral EMM cases reported in the literature from 1985 to 2015. Nineteen articles were identified from the literature and included 24 individual cases with a total of 34 vertebral or intraspinal EMM. Forty-two percent (10\/24) of patients with vertebral or intraspinal EMM had WHO Grade I tumors. Furthermore, 25% (6\/24) of vertebral and intraspinal EMM occurred after the primary tumor but prior to any recurrence.<\/jats:p>\n<jats:p>This paper highlights that vertebral and intraspinal EMM can occur in patients with WHO Grade I meningiomas and can occur before tumor recurrence. This challenges the notion that EMM are seen primarily in high-grade atypical and anaplastic meningiomas.<\/jats:p>","DOI":"10.3171\/2016.5.spine151457","type":"journal-article","created":{"date-parts":[[2016,7,15]],"date-time":"2016-07-15T15:29:24Z","timestamp":1468596564000},"page":"775-781","source":"Crossref","is-referenced-by-count":9,"title":["Intracranial meningioma with vertebral or intraspinal metastasis: report of 2 cases and review of the literature"],"prefix":"10.3171","volume":"25","author":[{"given":"Ranjodh","family":"Singh","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher","family":"Ryan","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Muhammad O.","family":"Chohan","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Department of Neurosurgery, University of New Mexico Comprehensive Cancer Center, Albuquerque, New Mexico; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jamie","family":"Tisnado","sequence":"additional","affiliation":[{"name":"Radiology, Memorial Sloan Kettering Cancer Center, New York, New York;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Georgios F.","family":"Hadjigeorgiou","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Red Cross Hospital, Athens, Greece"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Mark H.","family":"Bilsky","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-spine151457","series-title":"Mayo Clin Proc","doi-asserted-by":"publisher","first-page":"1129","DOI":"10.4065\/74.11.1129","article-title":"Meningioma metastatic to the lung","volume":"74","author":"Adlakha","year":"1999"},{"key":"b2-spine151457","series-title":"Acta Neurol Scand","first-page":"368","article-title":"Malignant meningioma metastasizing through the cerebrospinal pathway","volume":"85","author":"Akimura","year":"1992"},{"key":"b3-spine151457","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"4506","DOI":"10.1002\/cncr.26065","article-title":"Pulmonary metastases in patients with recurrent, treatment-resistant meningioma: prognosis and identification by 111Indium-octreotide imaging","volume":"117","author":"Alexandru","year":"2011"},{"key":"b4-spine151457","series-title":"No Shinkei Geka","first-page":"785","article-title":"[Angioblastic meningioma with metastases to the vertebra and adjacent bones: a case report.]","volume":"16","author":"Asai","year":"1988"},{"key":"b5-spine151457","series-title":"Virchows Arch","doi-asserted-by":"publisher","first-page":"591","DOI":"10.1007\/s00428-007-0392-9","article-title":"\u201cBenign\u201d metastatic meningioma: clinico-pathological analysis of one case metastasising to the lung and overview on the concepts of either primitive or metastatic meningiomas of the lung","volume":"450","author":"Asioli","year":"2007"},{"key":"b6-spine151457","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"121","DOI":"10.1016\/j.wneu.2015.02.041","article-title":"Scalp metastases of recurrent meningiomas: aggressive behavior or surgical seeding?","volume":"84","author":"Avecillas-Chasin","year":"2015"},{"key":"b7-spine151457","series-title":"Diagn Cytopathol","doi-asserted-by":"publisher","first-page":"291","DOI":"10.1002\/(SICI)1097-0339(199905)20:5<291::AID-DC8>3.0.CO;2-R","article-title":"Metastatic meningioma in fine-needle aspiration (FNA) of the lung: cytomorphologic finding","volume":"20","author":"Baisden","year":"1999"},{"key":"b8-spine151457","series-title":"Br J Radiol","doi-asserted-by":"publisher","first-page":"e259","DOI":"10.1259\/bjr\/11276652","article-title":"Metastatic meningioma: positron emission tomography CT imaging findings","volume":"83","author":"Brennan","year":"2010"},{"key":"b9-spine151457","series-title":"Cancer","doi-asserted-by":"publisher","first-page":"1427","DOI":"10.1002\/cncr.20926","article-title":"Cerebrospinal fluid-disseminated meningioma","volume":"103","author":"Chamberlain","year":"2005"},{"key":"b10-spine151457","series-title":"Spine (Phila Pa 1976)","doi-asserted-by":"publisher","first-page":"E1006","DOI":"10.1097\/01.brs.0000245952.71265.9b","article-title":"Intracranial malignant meningioma with multiple spinal metastases\u2014a case report and literature review: case report","volume":"31","author":"Chuang","year":"2006"},{"key":"b11-spine151457","series-title":"Acta Neurochir (Wien)","doi-asserted-by":"publisher","first-page":"935","DOI":"10.1007\/s007010170024","article-title":"Recurrent lumbosacral metastases from intracranial meningioma. 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