{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,24]],"date-time":"2026-09-24T01:30:32Z","timestamp":1790213432289,"version":"4.1.0"},"reference-count":172,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["FOC"],"published-print":{"date-parts":[[2016,9]]},"abstract":"<jats:p>The pathophysiology of NPH continues to provoke debate. Although guidelines and best-practice recommendations are well established, there remains a lack of consensus about the role of individual imaging modalities in characterizing specific features of the condition and predicting the success of CSF shunting. Variability of clinical presentation and imperfect responsiveness to shunting are obstacles to the application of novel imaging techniques. Few studies have sought to interpret imaging findings in the context of theories of NPH pathogenesis. In this paper, the authors discuss the major streams of thought for the evolution of NPH and the relevance of key imaging studies contributing to the understanding of the pathophysiology of this complex condition.<\/jats:p>","DOI":"10.3171\/2016.7.focus16194","type":"journal-article","created":{"date-parts":[[2016,9,1]],"date-time":"2016-09-01T03:39:30Z","timestamp":1472701170000},"page":"E11","source":"Crossref","is-referenced-by-count":75,"title":["Imaging normal pressure hydrocephalus: theories, techniques, and challenges"],"prefix":"10.3171","volume":"41","author":[{"given":"Nicole C. H.","family":"Keong","sequence":"first","affiliation":[{"name":"Department of Neurosurgery, National Neuroscience Institute and Duke-NUS Medical School, Singapore;"},{"name":"Neurosurgical Division, Department of Clinical Neurosciences, University of Cambridge, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alonso","family":"Pena","sequence":"additional","affiliation":[{"name":"SDA Bocconi School of Management, Milan, Italy"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Stephen J.","family":"Price","sequence":"additional","affiliation":[{"name":"Neurosurgical Division, Department of Clinical Neurosciences, University of Cambridge, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marek","family":"Czosnyka","sequence":"additional","affiliation":[{"name":"Neurosurgical Division, Department of Clinical Neurosciences, University of Cambridge, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Zofia","family":"Czosnyka","sequence":"additional","affiliation":[{"name":"Neurosurgical Division, Department of Clinical Neurosciences, University of Cambridge, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"John D.","family":"Pickard","sequence":"additional","affiliation":[{"name":"Neurosurgical Division, Department of Clinical Neurosciences, University of Cambridge, United Kingdom; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-focus16194","series-title":"Acta Pathol Jpn","first-page":"97","article-title":"Normal pressure hydrocephalus. 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