{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,25]],"date-time":"2026-07-25T04:05:32Z","timestamp":1784952332832,"version":"3.55.0"},"reference-count":26,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":["PED"],"published-print":{"date-parts":[[2017,1]]},"abstract":"<jats:sec>\n<jats:title>OBJECTIVE<\/jats:title>\n<jats:p>Young patients with moyamoya disease can exhibit infarction after revascularization surgery. This analysis of the characteristics of infarction after encephaloduroarteriosynangiosis (EDAS) in young patients with moyamoya disease was undertaken in an effort to elucidate the infarction mechanism.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>METHODS<\/jats:title>\n<jats:p>The authors retrospectively collected clinical information and reviewed pre- and postoperative MRI studies from cases involving patients younger than 18 years who underwent EDAS for the treatment of moyamoya disease between January 2012 and February 2015. Infarction patterns were categorized into watershed, territorial, or mixed pattern. The Wilcoxon rank sum test, chi-square test, and Fisher exact test were used to compare the clinical and imaging variables between patient groups. The characteristics of patients with and without postoperative infarction were compared using univariate and multivariate analysis. The cumulative proportion of patients without postoperative infarction according to operation stage was calculated using the Kaplan-Meier method and the resulting curves were compared using the log-rank test.<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>RESULTS<\/jats:title>\n<jats:p>In 100 patients, 171 EDAS procedures had been performed. There were 38 cases of preoperative infarction in 35 patients and 20 cases of postoperative infarction in 13 patients. Territorial infarction was more frequent in the postoperative infarction group than in the preoperative infarction group (55.0% vs 37.8%, p = 0.037). Infarction was more common on the bilateral or contralateral side of the operation after first-stage EDAS (9 [75.0%] of 12 infarctions) than in the second-stage operation (2 [25.0%] of 8 infarctions), but the difference was not statistically significant (p = 0.068). The frequency of postoperative infarction was not significantly different depending on the stage of the operation (p = 0.694).<\/jats:p><\/jats:sec>\n<jats:sec>\n<jats:title>CONCLUSIONS<\/jats:title>\n<jats:p>An acute infarction pattern after EDAS was more frequently territorial, suggesting an underlying occlusive mechanism. Operation stage did not affect the rate of postoperative infarction occurrence.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2016.7.peds16218","type":"journal-article","created":{"date-parts":[[2016,10,7]],"date-time":"2016-10-07T13:57:40Z","timestamp":1475848660000},"page":"1-7","source":"Crossref","is-referenced-by-count":27,"title":["Characteristics of infarction after encephaloduroarteriosynangiosis in young patients with moyamoya disease"],"prefix":"10.3171","volume":"19","author":[{"given":"Hyun Gi","family":"Kim","sequence":"first","affiliation":[{"name":"Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul; and"},{"name":"Department of Radiology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Seung-Koo","family":"Lee","sequence":"additional","affiliation":[{"name":"Department of Radiology and Research Institute of Radiological Science, Yonsei University College of Medicine, Seoul; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jung-Dong","family":"Lee","sequence":"additional","affiliation":[{"name":"Office of Biostatistics, Ajou University School of Medicine, Suwon, Korea"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-peds16218","series-title":"J Neurol Neurosurg Psychiatry","doi-asserted-by":"publisher","first-page":"38","DOI":"10.1136\/jnnp.2009.181487","article-title":"The different infarct patterns between adulthood-onset and childhood-onset moyamoya disease","volume":"82","author":"Cho HJ,","year":"2011","unstructured":"Cho HJ, Jung YH, Kim YD, Nam HS, Kim DS, Heo JH: The different infarct patterns between adulthood-onset and childhood-onset moyamoya disease. 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