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New implantable neuromodulation platforms, such as the Medtronic Activa PC+S DBS system, offer important data sources by providing chronic neural sensing capabilities and a means of investigating dynamic stimulation based on symptom measurements. The authors implanted in a single patient with ET an Activa PC+S system, a cortical strip of electrodes on the hand sensorimotor cortex, and therapeutic electrodes in the ventral intermediate nucleus of the thalamus. In this paper they describe the effectiveness of the platform when sensing cortical movement intentions while the patient actually performed and imagined performing movements. Additionally, they demonstrate dynamic closed-loop DBS based on several wearable sensor measurements of tremor intensity.<\/jats:p>","DOI":"10.3171\/2016.8.jns16536","type":"journal-article","created":{"date-parts":[[2016,11,18]],"date-time":"2016-11-18T15:00:03Z","timestamp":1479481203000},"page":"580-587","source":"Crossref","is-referenced-by-count":124,"title":["Chronic electrocorticography for sensing movement intention and closed-loop deep brain stimulation with wearable sensors in an essential tremor patient"],"prefix":"10.3171","volume":"127","author":[{"given":"Jeffrey A.","family":"Herron","sequence":"first","affiliation":[{"name":"Departments of Electrical Engineering,"},{"name":"NSF Engineering Research Center for Sensorimotor Neural Engineering, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Margaret C.","family":"Thompson","sequence":"additional","affiliation":[{"name":"Departments of Electrical Engineering,"},{"name":"NSF Engineering Research Center for Sensorimotor Neural Engineering, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Timothy","family":"Brown","sequence":"additional","affiliation":[{"name":"Philosophy,"},{"name":"NSF Engineering Research Center for Sensorimotor Neural Engineering, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Howard J.","family":"Chizeck","sequence":"additional","affiliation":[{"name":"Departments of Electrical Engineering,"},{"name":"Bioengineering, and"},{"name":"NSF Engineering Research Center for Sensorimotor Neural Engineering, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jeffrey G.","family":"Ojemann","sequence":"additional","affiliation":[{"name":"Neurological Surgery, University of Washington; and"},{"name":"NSF Engineering Research Center for Sensorimotor Neural Engineering, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew L.","family":"Ko","sequence":"additional","affiliation":[{"name":"Neurological Surgery, University of Washington; and"},{"name":"NSF Engineering Research Center for Sensorimotor Neural Engineering, Seattle, Washington"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1-jns16536","series-title":"Lancet","doi-asserted-by":"publisher","first-page":"1152","DOI":"10.1016\/S0140-6736(07)60544-3","article-title":"Clinical update: diagnosis and treatment of essential tremor","volume":"369","author":"Benito-Le\u00f3n J,","year":"2007","unstructured":"Benito-Le\u00f3n J, Louis ED: Clinical update: diagnosis and treatment of essential tremor. 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