{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,24]],"date-time":"2026-10-24T02:38:06Z","timestamp":1792809486579,"version":"4.5.0"},"reference-count":26,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,4]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>The aim of this study was to compare the clinical and angiographic outcomes of intracranial aneurysms with and without branches arising from the sac after Pipeline embolization device (PED) treatment.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>This retrospective 2-center comparative study included 116 patients with 157 aneurysms that were treated with PEDs. Aneurysms were divided into 2 groups: one group had branches arising from the sac and the other group did not. Study end points included total aneurysm occlusion assessed by angiography at 6 and 12 months, death or stroke, technical complications, in-stent stenosis, patency of covered branches, and transient ischemia.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>One hundred fifty-one aneurysms (96%) were located in the internal carotid artery. A branch arising from the sac was observed in 26 aneurysms. Complete occlusion was found in 120 of 156 aneurysms at 6 months (76.92% [95% CI 69.71%\u201382.84%]) and in 136 of 155 aneurysms at 12 months (87.74% [95% CI 81.28%\u201392.27%]). Total occlusion was more frequently observed in the group without a branch arising from the sac (84% vs 40% at 6 months, p &lt; 0.001; 93.10% vs 60% at 1 year, p &lt; 0.001). There were 4 (3.45% [95% CI 1.11%\u20139.12%]) cases of death or major stroke. Amaurosis fugax occurred in 3 patients. One patient experienced worsening of mass effect after treatment. No occlusion of branches arising from the aneurysm was observed. In-stent stenosis greater than 50% was observed in 1 case.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>Aneurysms treated with PEDs are less likely to be totally occluded if they have a branch arising from the sac than are aneurysms without these branches.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2017.10.jns172175","type":"journal-article","created":{"date-parts":[[2018,4,6]],"date-time":"2018-04-06T09:59:15Z","timestamp":1523008755000},"page":"1-7","source":"Crossref","is-referenced-by-count":18,"title":["Occlusion rates of intracranial aneurysms treated with the Pipeline embolization device: the role of branches arising from the sac"],"prefix":"10.3171","author":[{"given":"Felipe Padovani","family":"Trivelato","sequence":"first","affiliation":[{"name":"Division of Interventional Neuroradiology, Fel\u00edcio Rocho Hospital, Belo Horizonte, Minas Gerais; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marco T\u00falio","family":"Salles Rezende","sequence":"additional","affiliation":[{"name":"Division of Interventional Neuroradiology, Fel\u00edcio Rocho Hospital, Belo Horizonte, Minas Gerais; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alexandre Cordeiro","family":"Ulh\u00f4a","sequence":"additional","affiliation":[{"name":"Division of Interventional Neuroradiology, Fel\u00edcio Rocho Hospital, Belo Horizonte, Minas Gerais; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Luis","family":"Henrique de Castro-Afonso","sequence":"additional","affiliation":[{"name":"Division of Interventional Neuroradiology, Hospital das Cl\u00ednicas, Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Guilherme Seizem","family":"Nakiri","sequence":"additional","affiliation":[{"name":"Division of Interventional Neuroradiology, Hospital das Cl\u00ednicas, Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Daniel Giansante","family":"Abud","sequence":"additional","affiliation":[{"name":"Division of Interventional Neuroradiology, Hospital das Cl\u00ednicas, Medical School, University of S\u00e3o Paulo, Ribeir\u00e3o Preto, S\u00e3o Paulo, Brazil"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Neurosurgery","first-page":"40","article-title":"Long-term clinical and angiographic outcomes following Pipeline Embolization Device treatment of complex internal carotid artery aneurysms: five-year results of the Pipeline for uncoilable or failed aneurysms trial","volume":"80","author":"Becske T","year":"2017","unstructured":"Becske T, Brinjikji W, Potts MB, Kallmes DF, Shapiro M, Moran CJ, : Long-term clinical and angiographic outcomes following Pipeline Embolization Device treatment of complex internal carotid artery aneurysms: five-year results of the Pipeline for uncoilable or failed aneurysms trial. 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