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A 43-year-old man presented with 1 week of headache, dizziness, and nausea, which precipitously evolved to hemiplegia. CT venography confirmed CVT, and therapeutic heparin was initiated. He suffered a generalized seizure due to left parietal hemorrhage, which subsequently expanded. He developed signs of mass effect and herniation, heparin was discontinued, and he was taken to the operating room for clot evacuation and external ventricular drain placement. Intraoperatively, the dura was deflated, suggesting underlying SIH. Ventral T-1 CSF leak was identified, which failed multiple epidural blood patches and required primary repair. The patient ultimately made a complete recovery. Systematic review identified 29 publications describing 36 cases of SIH-associated CVT. Among 31 patients for whom long-term neurological outcome was reported, 25 (81%) recovered completely. Underlying coagulopathy\/risk factors were identified in 11 patients (31%). CVT is a rare and potentially lethal sequela occurring in 2% of SIH cases. Awareness of the condition is poor, risking morbid complications. Evaluation and treatment should be directed toward identification and treatment of occult CSF leaks. Encouragingly, good neurological outcomes can be achieved through vigilant multidisciplinary neurosurgical and neurocritical care.<\/jats:p>","DOI":"10.3171\/2017.10.spine17806","type":"journal-article","created":{"date-parts":[[2018,3,30]],"date-time":"2018-03-30T14:02:24Z","timestamp":1522418544000},"page":"669-678","source":"Crossref","is-referenced-by-count":12,"title":["Spontaneous occult intracranial hypotension precipitating life-threatening cerebral venous thrombosis: case report"],"prefix":"10.3171","volume":"28","author":[{"given":"Avital","family":"Perry","sequence":"first","affiliation":[{"name":"Departments of Neurologic Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S.","family":"Graffeo","sequence":"additional","affiliation":[{"name":"Departments of Neurologic Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Waleed","family":"Brinjikji","sequence":"additional","affiliation":[{"name":"Radiology-Diagnostic,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William R.","family":"Copeland","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Tenwek Hospital, Bomet, Kenya"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Alejandro A.","family":"Rabinstein","sequence":"additional","affiliation":[{"name":"Neurology, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Link","sequence":"additional","affiliation":[{"name":"Departments of Neurologic Surgery,"},{"name":"Otolaryngology\u2013Head and Neck Surgery, Mayo Clinic, Rochester, Minnesota; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Case Rep Neurol Med","first-page":"913465","article-title":"Intracranial hypotension with multiple complications: an unusual case report","volume":"2013","author":"Ade S","year":"2013","unstructured":"Ade S, Moonis M: Intracranial hypotension with multiple complications: an unusual case report. 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