{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,7,11]],"date-time":"2026-07-11T13:37:00Z","timestamp":1783777020395,"version":"3.55.0"},"reference-count":13,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"4","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2017,10]]},"abstract":"OBJECTIVE<\/jats:title>Grabb\u2019s line\u2014the perpendicular distance from the basion-C2 line (pB-C2)\u2014is a widely used radiographic measurement with significant clinical implications in patients with a complex Chiari malformation. Rigorous demonstration of the reproducibility of this measurement has not previously been reported. The authors report a standardized measurement technique with excellent inter- and intrarater reliability on T1-weighted sagittal MRI.<\/jats:p><\/jats:sec>METHODS<\/jats:title>The authors developed a standardized measurement technique that included specifications of midline slice selection, landmark and reference line definitions, and measurement technique on T1-weighted sagittal images. Twenty MR images were reviewed by 2 pediatric neurosurgeons, 1 pediatric radiologist, and 1 undergraduate student. Measurements were performed using the technique specified on 2 separate occasions. Intrarater and interrater reliabilities were calculated using the intraclass correlation coefficient.<\/jats:p><\/jats:sec>RESULTS<\/jats:title>A combined interrater reliability of 0.879 was achieved for the pB-C2, and 0.916 for the clival-canal angle, another measure of interest in patients with complex Chiari malformations. Intrarater reliability for these measurements exceeded 0.858 for all 4 reviewers.<\/jats:p><\/jats:sec>CONCLUSIONS<\/jats:title>Grabb\u2019s line\u2014the pB-C2\u2014can be measured with excellent reliability using a standardized measurement protocol. Individual clinicians and collaborative databases should consider using validated measurement techniques to guide clinical decision making in patients with craniocervical junction pathology.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2017.5.peds17181","type":"journal-article","created":{"date-parts":[[2017,8,11]],"date-time":"2017-08-11T13:59:11Z","timestamp":1502459951000},"page":"352-356","source":"Crossref","is-referenced-by-count":10,"title":["Standardized method for the measurement of Grabb\u2019s line and clival-canal angle"],"prefix":"10.3171","volume":"20","author":[{"given":"Jonathan E.","family":"Martin","sequence":"first","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Connecticut Children\u2019s Medical Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Markus","family":"Bookland","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Connecticut Children\u2019s Medical Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Douglas","family":"Moote","sequence":"additional","affiliation":[{"name":"Department of Radiology, Connecticut Children\u2019s Medical Center, Hartford, Connecticut"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Catherine","family":"Cebulla","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Department of Surgery, Connecticut Children\u2019s Medical Center; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"134","DOI":"10.3171\/2012.3.PEDS11340","article-title":"Complex Chiari malformations in children: an analysis of preoperative risk factors for occipitocervical fusion","volume":"10","author":"Bollo RJ","year":"2012","unstructured":"Bollo RJ, Riva-Cambrin J, Brockmeyer MM, Brockmeyer DL: Complex Chiari malformations in children: an analysis of preoperative risk factors for occipitocervical fusion. 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