{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,3,31]],"date-time":"2026-03-31T11:31:30Z","timestamp":1774956690135,"version":"3.50.1"},"reference-count":40,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The potential loss of motor function after cerebral hemispherectomy is a common cause of anguish for patients, their families, and their physicians. The deficits these patients face are individually unique, but as a whole they provide a framework to understand the mechanisms underlying cortical reorganization of motor function. This study investigated whether preoperative functional MRI (fMRI) and diffusion tensor imaging (DTI) could predict the postoperative preservation of hand motor function.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>Thirteen independent reviewers analyzed sensorimotor fMRI and colored fractional anisotropy (CoFA)\u2013DTI maps in 25 patients undergoing functional hemispherectomy for treatment of intractable seizures. Pre- and postoperative gross hand motor function were categorized and correlated with fMRI and DTI findings, specifically, abnormally located motor activation on fMRI and corticospinal tract atrophy on DTI.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Normal sensorimotor cortical activation on preoperative fMRI was significantly associated with severe decline in postoperative motor function, demonstrating 92.9% sensitivity (95% CI 0.661\u20130.998) and 100% specificity (95% CI 0.715\u20131.00). Bilaterally robust, symmetric corticospinal tracts on CoFA-DTI maps were significantly associated with severe postoperative motor decline, demonstrating 85.7% sensitivity (95% CI 0.572\u20130.982) and 100% specificity (95% CI 0.715\u20131.00). Interpreting the fMR images, the reviewers achieved a Fleiss\u2019 kappa coefficient (\u03ba) for interrater agreement of \u03ba = 0.69, indicating good agreement (p &lt; 0.01). When interpreting the CoFA-DTI maps, the reviewers achieved \u03ba = 0.64, again indicating good agreement (p &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Functional hemispherectomy offers a high potential for seizure freedom without debilitating functional deficits in certain instances. Patients likely to retain preoperative motor function can be identified prior to hemispherectomy, where fMRI or DTI suggests that cortical reorganization of motor function has occurred prior to the operation.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2017.7.peds17137","type":"journal-article","created":{"date-parts":[[2017,11,3]],"date-time":"2017-11-03T13:55:37Z","timestamp":1509717337000},"page":"81-89","source":"Crossref","is-referenced-by-count":19,"title":["Corticospinal tract atrophy and motor fMRI predict motor preservation after functional cerebral hemispherectomy"],"prefix":"10.3171","volume":"21","author":[{"given":"Anthony C.","family":"Wang","sequence":"first","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"George M.","family":"Ibrahim","sequence":"additional","affiliation":[{"name":"Division of Neurosurgery, Hospital for Sick Children and Toronto Western Hospital, Toronto, Ontario, Canada; Departments of"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Andrew V.","family":"Poliakov","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Page I.","family":"Wang","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Aria","family":"Fallah","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Gary W.","family":"Mathern","sequence":"additional","affiliation":[{"name":"Departments of Neurosurgery and"},{"name":"Psychiatry and BioBehavioral Sciences, The Brain Research Institute, University of California, Los Angeles, California;"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Robert T.","family":"Buckley","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Kelly","family":"Collins","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Alexander G.","family":"Weil","sequence":"additional","affiliation":[{"name":"Division of Pediatric Neurosurgery, Department of Surgery, Sainte Justine Hospital, University of Montreal, Quebec, Canada"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Hillary A.","family":"Shurtleff","sequence":"additional","affiliation":[{"name":"Neurology\/Division of Pediatric Neurology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Molly H.","family":"Warner","sequence":"additional","affiliation":[{"name":"Neurology\/Division of Pediatric Neurology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Francisco A.","family":"Perez","sequence":"additional","affiliation":[{"name":"Radiology, University of Washington, Seattle Children\u2019s Hospital, Seattle, Washington; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Dennis W.","family":"Shaw","sequence":"additional","affiliation":[{"name":"Radiology, University of Washington, Seattle Children\u2019s Hospital, Seattle, Washington; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jason N.","family":"Wright","sequence":"additional","affiliation":[{"name":"Radiology, University of Washington, Seattle Children\u2019s Hospital, Seattle, Washington; and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Russell P.","family":"Saneto","sequence":"additional","affiliation":[{"name":"Neurology\/Division of Pediatric Neurology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Edward J.","family":"Novotny","sequence":"additional","affiliation":[{"name":"Neurology\/Division of Pediatric Neurology, and"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Amy","family":"Lee","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Samuel R.","family":"Browd","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]},{"given":"Jeffrey G.","family":"Ojemann","sequence":"additional","affiliation":[{"name":"Neurological Surgery,"}],"role":[{"role":"author","vocabulary":"crossref"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Exp Brain Res","doi-asserted-by":"publisher","first-page":"419","DOI":"10.1007\/BF00231167","article-title":"Reorganisation of descending motor pathways in patients after hemispherectomy and severe hemispheric lesions demonstrated by magnetic brain stimulation","volume":"83","author":"Benecke R","year":"1991","unstructured":"Benecke R, Meyer BU, Freund HJ: Reorganisation of descending motor pathways in patients after hemispherectomy and severe hemispheric lesions demonstrated by magnetic brain stimulation. Exp Brain Res 83:419\u2013426, 1991202224710.1007\/BF00231167"},{"key":"b2","series-title":"Brain","doi-asserted-by":"publisher","first-page":"653","DOI":"10.1093\/brain\/96.4.653","article-title":"Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey","volume":"96","author":"Brinkman J","year":"1973","unstructured":"Brinkman J, Kuypers HG: Cerebral control of contralateral and ipsilateral arm, hand and finger movements in the split-brain rhesus monkey. Brain 96:653\u2013674, 197310.1093\/brain\/96.4.6534204228"},{"key":"b3","series-title":"Stroke","doi-asserted-by":"publisher","first-page":"112","DOI":"10.1161\/01.STR.29.1.112","article-title":"Pilot study of functional MRI to assess cerebral activation of motor function after poststroke hemiparesis","volume":"29","author":"Cao Y","year":"1998","unstructured":"Cao Y, D\u2019Olhaberriague L, Vikingstad EM, Levine SR, Welch KM: Pilot study of functional MRI to assess cerebral activation of motor function after poststroke hemiparesis. Stroke 29:112\u2013122, 1998944533810.1161\/01.STR.29.1.112"},{"key":"b4","series-title":"Neuropsychologia","doi-asserted-by":"publisher","first-page":"1192","DOI":"10.1016\/j.neuropsychologia.2009.12.013","article-title":"Sensorimotor function and sensorimotor tracts after hemispherectomy","volume":"48","author":"Choi JT","year":"2010","unstructured":"Choi JT, Vining EP, Mori S, Bastian AJ: Sensorimotor function and sensorimotor tracts after hemispherectomy. Neuropsychologia 48:1192\u20131199, 201010.1016\/j.neuropsychologia.2009.12.01320018199"},{"key":"b5","series-title":"J Child Neurol","doi-asserted-by":"publisher","first-page":"64","DOI":"10.1177\/08830738050200011101","article-title":"Residual motor control and cortical representations of function following hemispherectomy: effects of etiology","volume":"20","author":"de Bode S","year":"2005","unstructured":"de Bode S, Firestine A, Mathern GW, Dobkin B: Residual motor control and cortical representations of function following hemispherectomy: effects of etiology. J Child Neurol 20:64\u201375, 200510.1177\/08830738050200011101"},{"key":"b6","series-title":"Neurorehabil Neural Repair","doi-asserted-by":"publisher","first-page":"497","DOI":"10.1177\/1545968307299523","article-title":"Locomotor training remodels fMRI sensorimotor cortical activations in children after cerebral hemispherectomy","volume":"21","author":"de Bode S","year":"2007","unstructured":"de Bode S, Mathern GW, Bookheimer S, Dobkin B: Locomotor training remodels fMRI sensorimotor cortical activations in children after cerebral hemispherectomy. Neurorehabil Neural Repair 21:497\u2013508, 200710.1177\/1545968307299523"},{"key":"b7","series-title":"Neurosurgery 60 (2 Suppl)","first-page":"ONS19","article-title":"Vertical parasagittal hemispherotomy: surgical procedures and clinical long-term outcomes in a population of 83 children","author":"Delalande O","year":"2007","unstructured":"Delalande O, Bulteau C, Dellatolas G, Fohlen M, Jalin C, Buret V, : Vertical parasagittal hemispherotomy: surgical procedures and clinical long-term outcomes in a population of 83 children. Neurosurgery 60 (2 Suppl):ONS19\u2013ONS32, 2007"},{"key":"b8","series-title":"Brain","doi-asserted-by":"publisher","first-page":"556","DOI":"10.1093\/brain\/awg052","article-title":"Clinical outcomes of hemispherectomy for epilepsy in childhood and adolescence","volume":"126","author":"Devlin AM","year":"2003","unstructured":"Devlin AM, Cross JH, Harkness W, Chong WK, Harding B, Vargha-Khadem F, : Clinical outcomes of hemispherectomy for epilepsy in childhood and adolescence. Brain 126:556\u2013566, 20031256627710.1093\/brain\/awg052"},{"key":"b9","series-title":"Psychol Bull","doi-asserted-by":"publisher","first-page":"378","DOI":"10.1037\/h0031619","article-title":"Measuring nominal scale agreement among many raters","volume":"76","author":"Fleiss JL","year":"1971","unstructured":"Fleiss JL: Measuring nominal scale agreement among many raters. Psychol Bull 76:378\u2013382, 197110.1037\/h0031619"},{"key":"b10","series-title":"Arch Neurol","doi-asserted-by":"publisher","first-page":"606","DOI":"10.1001\/archneur.1967.00470240044005","article-title":"Dyspraxia following division of the cerebral commissures","volume":"16","author":"Gazzaniga MS","year":"1967","unstructured":"Gazzaniga MS, Bogen JE, Sperry RW: Dyspraxia following division of the cerebral commissures. Arch Neurol 16:606\u2013612, 1967602606910.1001\/archneur.1967.00470240044005"},{"key":"b11","series-title":"J Child Neurol","doi-asserted-by":"publisher","first-page":"1548","DOI":"10.1177\/0883073812455101","article-title":"Cerebellar pathway changes following cerebral hemispherectomy","volume":"21","author":"Govindan RM","year":"2013","unstructured":"Govindan RM, Brescoll J, Chugani HT: Cerebellar pathway changes following cerebral hemispherectomy. J Child Neurol 21:1548\u20131554, 201310.1177\/0883073812455101"},{"key":"b12","series-title":"Pediatr Neurol","doi-asserted-by":"publisher","first-page":"337","DOI":"10.1016\/S0887-8994(98)00082-4","article-title":"Regionalized sensorimotor plasticity after hemispherectomy fMRI evaluation","volume":"19","author":"Graveline CJ","year":"1998","unstructured":"Graveline CJ, Mikulis DJ, Crawley AP, Hwang PA: Regionalized sensorimotor plasticity after hemispherectomy fMRI evaluation. Pediatr Neurol 19:337\u2013342, 1998988013610.1016\/S0887-8994(98)00082-4"},{"key":"b13","series-title":"Brain Res Brain Res Rev","doi-asserted-by":"publisher","first-page":"169","DOI":"10.1016\/S0165-0173(01)00092-3","article-title":"Plasticity of the human motor cortex and recovery from stroke","volume":"36","author":"Hallett M","year":"2001","unstructured":"Hallett M: Plasticity of the human motor cortex and recovery from stroke. Brain Res Brain Res Rev 36:169\u2013174, 200110.1016\/S0165-0173(01)00092-311690613"},{"key":"b14","series-title":"Brain","doi-asserted-by":"publisher","first-page":"2432","DOI":"10.1093\/brain\/123.12.2432","article-title":"The reorganization of sensorimotor function in children after hemispherectomy. A functional MRI and somatosensory evoked potential study","volume":"123","author":"Holloway V","year":"2000","unstructured":"Holloway V, Gadian DG, Vargha-Khadem F, Porter DA, Boyd SG, Connelly A: The reorganization of sensorimotor function in children after hemispherectomy. A functional MRI and somatosensory evoked potential study. Brain 123:2432\u20132444, 200010.1093\/brain\/123.12.243211099446"},{"key":"b15","series-title":"Epilepsy Behav","doi-asserted-by":"publisher","first-page":"281","DOI":"10.1016\/j.yebeh.2015.07.039","article-title":"Thalamocortical connectivity is enhanced following functional hemispherotomy for intractable lateralized epilepsy","volume":"51","author":"Ibrahim GM","year":"2015","unstructured":"Ibrahim GM, Morgan BR, Smith ML, Kerr E, Donner E, Go CY, : Thalamocortical connectivity is enhanced following functional hemispherotomy for intractable lateralized epilepsy. Epilepsy Behav 51:281\u2013285, 201510.1016\/j.yebeh.2015.07.03926318790"},{"key":"b16","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"1712","DOI":"10.1212\/01.WNL.0000127109.14569.C3","article-title":"Cerebral hemispherectomy: hospital course, seizure, developmental, language, and motor outcomes","volume":"62","author":"Jonas R","year":"2004","unstructured":"Jonas R, Nguyen S, Hu B, Asarnow RF, LoPresti C, Curtiss S, : Cerebral hemispherectomy: hospital course, seizure, developmental, language, and motor outcomes. Neurology 62:1712\u20131721, 20041515946710.1212\/01.WNL.0000127109.14569.C3"},{"key":"b17","series-title":"Am J Physiol","doi-asserted-by":"publisher","first-page":"138","DOI":"10.1152\/ajplegacy.1936.115.1.138","article-title":"Age and other factors in motor recovery from precentral lesions in monkeys","volume":"115","author":"Kennard MA","year":"1936","unstructured":"Kennard MA: Age and other factors in motor recovery from precentral lesions in monkeys. Am J Physiol 115:138\u2013146, 193610.1152\/ajplegacy.1936.115.1.138"},{"key":"b18","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"887","DOI":"10.1212\/01.WNL.0000090107.04681.5B","article-title":"Hemispherectomy for intractable unihemispheric epilepsy etiology vs outcome","volume":"61","author":"Kossoff EH","year":"2003","unstructured":"Kossoff EH, Vining EP, Pillas DJ, Pyzik PL, Avellino AM, Carson BS, : Hemispherectomy for intractable unihemispheric epilepsy etiology vs outcome. Neurology 61:887\u2013890, 200310.1212\/01.WNL.0000090107.04681.5B14557554"},{"key":"b19","series-title":"AJNR Am J Neuroradiol","doi-asserted-by":"publisher","first-page":"924","DOI":"10.3174\/ajnr.A4647","article-title":"Cerebral reorganization after hemispherectomy: a DTI study","volume":"37","author":"Meoded A","year":"2016","unstructured":"Meoded A, Faria AV, Hartman AL, Jallo GI, Mori S, Johnston MV, : Cerebral reorganization after hemispherectomy: a DTI study. AJNR Am J Neuroradiol 37:924\u2013931, 201610.3174\/ajnr.A464726767710"},{"key":"b20","series-title":"Epilepsy Surgery: Principles and Controversies","year":"2006","unstructured":"Miller JW, Silbergeld DL (eds): Epilepsy Surgery: Principles and Controversies. New York: Taylor & Francis, 2006"},{"key":"b21","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"927","DOI":"10.1212\/WNL.0b013e31820f8583","article-title":"Reorganization of large-scale physiology in hand motor cortex following hemispheric stroke","volume":"76","author":"Miller KJ","year":"2011","unstructured":"Miller KJ, Abel TJ, Hebb AO, Ojemann JG: Reorganization of large-scale physiology in hand motor cortex following hemispheric stroke. Neurology 76:927\u2013929, 20112138333010.1212\/WNL.0b013e31820f8583"},{"key":"b22","series-title":"Neurology","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1212\/WNL.0b013e31827dead9","article-title":"Longitudinal seizure outcome and prognostic predictors after hemispherectomy in 170 children","volume":"80","author":"Moosa AN","year":"2013","unstructured":"Moosa AN, Gupta A, Jehi L, Marashly A, Cosmo G, Lachhwani D, : Longitudinal seizure outcome and prognostic predictors after hemispherectomy in 170 children. Neurology 80:253\u2013260, 20132322354110.1212\/WNL.0b013e31827dead9"},{"key":"b23","series-title":"Epilepsia","doi-asserted-by":"publisher","first-page":"1771","DOI":"10.1111\/epi.12342","article-title":"Long-term functional outcomes and their predictors after hemispherectomy in 115 children","volume":"54","author":"Moosa AN","year":"2013","unstructured":"Moosa AN, Jehi L, Marashly A, Cosmo G, Lachhwani D, Wyllie E, : Long-term functional outcomes and their predictors after hemispherectomy in 115 children. Epilepsia 54:1771\u20131779, 20132398075910.1111\/epi.12342"},{"key":"b24","series-title":"Acta Radiol","doi-asserted-by":"publisher","first-page":"778","DOI":"10.1080\/02841850410001303","article-title":"Diffusion property following functional hemispherectomy in hemimegalencephaly","volume":"45","author":"Mori H","year":"2004","unstructured":"Mori H, Aoki S, Abe O, Hayashi N, Masutani Y, Ohtomo K, : Diffusion property following functional hemispherectomy in hemimegalencephaly. Acta Radiol 45:778\u2013781, 20041562452210.1080\/02841850410001303"},{"key":"b25","series-title":"Ann Neurol","doi-asserted-by":"publisher","first-page":"705","DOI":"10.1002\/ana.410420506","article-title":"Ontogeny of ipsilateral corticospinal projections: a developmental study with transcranial magnetic stimulation","volume":"42","author":"M\u00fcller K","year":"1997","unstructured":"M\u00fcller K, Kass-Iliyya F, Reitz M: Ontogeny of ipsilateral corticospinal projections: a developmental study with transcranial magnetic stimulation. Ann Neurol 42:705\u2013711, 199710.1002\/ana.4104205069392569"},{"key":"b26","series-title":"Neuroradiology","doi-asserted-by":"publisher","first-page":"1093","DOI":"10.1007\/s00234-015-1564-y","article-title":"Functional hemispherectomy: postoperative motor state and correlation to preoperative DTI","volume":"57","author":"Nelles M","year":"2015","unstructured":"Nelles M, Urbach H, Sassen R, Sch\u00f6ne-Bake JC, Tschampa H, Tr\u00e4ber F, : Functional hemispherectomy: postoperative motor state and correlation to preoperative DTI. Neuroradiology 57:1093\u20131102, 20152626383910.1007\/s00234-015-1564-y"},{"key":"b27","series-title":"Electroencephalogr Clin Neurophysiol","doi-asserted-by":"publisher","first-page":"230","DOI":"10.1016\/0168-5597(94)90045-0","article-title":"Differentiation of sensorimotor neuronal structures responsible for induction of motor evoked potentials, attenuation in detection of somatosensory stimuli, and induction of sensation of movement by mapping of optimal current directions","volume":"93","author":"Pascual-Leone A","year":"1994","unstructured":"Pascual-Leone A, Cohen LG, Brasil-Neto JP, Valls-Sol\u00e9 J, Hallett M: Differentiation of sensorimotor neuronal structures responsible for induction of motor evoked potentials, attenuation in detection of somatosensory stimuli, and induction of sensation of movement by mapping of optimal current directions. Electroencephalogr Clin Neurophysiol 93:230\u2013236, 1994751580010.1016\/0168-5597(94)90045-0"},{"key":"b28","series-title":"Neuroreport","doi-asserted-by":"publisher","first-page":"2068","DOI":"10.1097\/00001756-199609020-00002","article-title":"Reorganization of human cortical motor output maps following traumatic forearm amputation","volume":"7","author":"Pascual-Leone A","year":"1996","unstructured":"Pascual-Leone A, Peris M, Tormos JM, Pascual AP, Catal\u00e1 MD: Reorganization of human cortical motor output maps following traumatic forearm amputation. Neuroreport 7:2068\u20132070, 199610.1097\/00001756-199609020-000028930960"},{"key":"b29","series-title":"Electroencephalogr Clin Neurophysiol Suppl","first-page":"157","article-title":"Applications of transcranial magnetic stimulation in studies on motor learning","volume":"51","author":"Pascual-Leone A","year":"1999","unstructured":"Pascual-Leone A, Tarazona F, Catal\u00e1 MD: Applications of transcranial magnetic stimulation in studies on motor learning. Electroencephalogr Clin Neurophysiol Suppl 51:157\u2013161, 199910590947"},{"key":"b30","series-title":"Curr Opin Neurobiol","doi-asserted-by":"publisher","first-page":"232","DOI":"10.1016\/S0959-4388(00)00081-7","article-title":"Transcranial magnetic stimulation in cognitive neuroscience\u2014virtual lesion, chronometry, and functional connectivity","volume":"10","author":"Pascual-Leone A","year":"2000","unstructured":"Pascual-Leone A, Walsh V, Rothwell J: Transcranial magnetic stimulation in cognitive neuroscience\u2014virtual lesion, chronometry, and functional connectivity. Curr Opin Neurobiol 10:232\u2013237, 200010.1016\/S0959-4388(00)00081-7"},{"key":"b31","series-title":"J Child Neurol","doi-asserted-by":"publisher","first-page":"292","DOI":"10.1177\/088307380201700411","article-title":"Interhemispheric reorganization of motor hand function to the primary motor cortex predicted with functional magnetic resonance imaging and transcranial magnetic stimulation","volume":"17","author":"Rutten GJ","year":"2002","unstructured":"Rutten GJ, Ramsey NF, van Rijen PC, Franssen H, van Veelen CW: Interhemispheric reorganization of motor hand function to the primary motor cortex predicted with functional magnetic resonance imaging and transcranial magnetic stimulation. J Child Neurol 17:292\u2013297, 200210.1177\/08830738020170041112088086"},{"issue":"1","key":"b32","series-title":"Neurosurg Focus","doi-asserted-by":"publisher","first-page":"E12","DOI":"10.3171\/2009.4.FOCUS0981","article-title":"Classification of contralateral and ipsilateral finger movements for electrocorticographic brain-computer interfaces","volume":"27","author":"Scherer R","year":"2009","unstructured":"Scherer R, Zanos SP, Miller KJ, Rao RP, Ojemann JG: Classification of contralateral and ipsilateral finger movements for electrocorticographic brain-computer interfaces. Neurosurg Focus 27(1):E12, 20091956988710.3171\/2009.4.FOCUS0981"},{"key":"b33","series-title":"Neurosurgery","first-page":"509","article-title":"Hemispherical deafferentation: an alternative to functional hemispherectomy","volume":"36","author":"Schramm J","year":"1995","unstructured":"Schramm J, Behrens E, Entzian W: Hemispherical deafferentation: an alternative to functional hemispherectomy. Neurosurgery 36:509\u2013516, 19957753351"},{"key":"b34","series-title":"J Neurosurg Pediatr","doi-asserted-by":"publisher","first-page":"500","DOI":"10.3171\/2009.11.PEDS09248","article-title":"Functional magnetic resonance imaging for presurgical evaluation of very young pediatric patients with epilepsy","volume":"5","author":"Shurtleff H","year":"2010","unstructured":"Shurtleff H, Warner M, Poliakov A, Bournival B, Shaw DW, Ishak G, : Functional magnetic resonance imaging for presurgical evaluation of very young pediatric patients with epilepsy. J Neurosurg Pediatr 5:500\u2013506, 20102043326410.3171\/2009.11.PEDS09248"},{"key":"b35","series-title":"Neuropediatrics","doi-asserted-by":"publisher","first-page":"159","DOI":"10.1055\/s-2001-16619","article-title":"Functional MRI in a 6-year-old boy with unilateral cortical malformation: concordant representation of both hands in the unaffected hemisphere","volume":"32","author":"Staudt M","year":"2001","unstructured":"Staudt M, Pieper T, Grodd W, Winkler P, Holthausen H, Kr\u00e4geloh-Mann I: Functional MRI in a 6-year-old boy with unilateral cortical malformation: concordant representation of both hands in the unaffected hemisphere. Neuropediatrics 32:159\u2013161, 200110.1055\/s-2001-16619"},{"key":"b36","series-title":"Brain Res","doi-asserted-by":"publisher","first-page":"155","DOI":"10.1016\/0006-8993(81)90951-3","article-title":"Contrasting neuronal activity in the ipsilateral and contralateral supplementary motor areas in relation to a movement of monkey\u2019s distal hindlimb","volume":"222","author":"Tanji J","year":"1981","unstructured":"Tanji J, Kurata K: Contrasting neuronal activity in the ipsilateral and contralateral supplementary motor areas in relation to a movement of monkey\u2019s distal hindlimb. Brain Res 222:155\u2013158, 198110.1016\/0006-8993(81)90951-37296262"},{"key":"b37","series-title":"Pediatr Res","doi-asserted-by":"publisher","first-page":"756","DOI":"10.1038\/pr.2013.45","article-title":"Quantification of white matter injury following neonatal stroke with serial DTI","volume":"73","author":"van der Aa NE","year":"2013","unstructured":"van der Aa NE, Northington FJ, Stone BS, Groenendaal F, Benders MJ, Porro G, : Quantification of white matter injury following neonatal stroke with serial DTI. Pediatr Res 73:756\u2013762, 201310.1038\/pr.2013.45"},{"key":"b38","series-title":"Neuroscience","doi-asserted-by":"publisher","first-page":"625","DOI":"10.1016\/S0306-4522(99)00482-0","article-title":"Developmental neuroplasticity in a model of cerebral hemispherectomy and stroke","volume":"95","author":"Villablanca JR","year":"2000","unstructured":"Villablanca JR, Hovda DA: Developmental neuroplasticity in a model of cerebral hemispherectomy and stroke. Neuroscience 95:625\u2013637, 200010.1016\/S0306-4522(99)00482-0"},{"key":"b39","series-title":"Epilepsy Res","doi-asserted-by":"publisher","first-page":"253","DOI":"10.1016\/j.eplepsyres.2012.10.015","article-title":"fMRI and DTI assessment of patients undergoing radical epilepsy surgery","volume":"104","author":"Zhang J","year":"2013","unstructured":"Zhang J, Mei S, Liu Q, Liu W, Chen H, Xia H, : fMRI and DTI assessment of patients undergoing radical epilepsy surgery. Epilepsy Res 104:253\u2013263, 20132334032910.1016\/j.eplepsyres.2012.10.015"},{"key":"b40","series-title":"Epilepsia","first-page":"e98","article-title":"Predicting hand function after hemispherotomy: TMS versus fMRI in hemispheric polymicrogyria","volume":"53","author":"Zsoter A","year":"2012","unstructured":"Zsoter A, Pieper T, Kudernatsch M, Staudt M: Predicting hand function after hemispherotomy: TMS versus fMRI in hemispheric polymicrogyria. Epilepsia 53:e98\u2013e101, 2012"}],"container-title":["Journal of Neurosurgery: Pediatrics"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/21\/1\/article-p81.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/21\/1\/article-p81.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg-pediatr\/21\/1\/article-p81.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,4,15]],"date-time":"2023-04-15T13:50:50Z","timestamp":1681566650000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg-pediatr\/21\/1\/article-p81.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2018,1]]},"references-count":40,"journal-issue":{"issue":"1"},"URL":"https:\/\/doi.org\/10.3171\/2017.7.peds17137","relation":{},"ISSN":["1933-0707","1933-0715"],"issn-type":[{"value":"1933-0707","type":"print"},{"value":"1933-0715","type":"electronic"}],"subject":[],"published":{"date-parts":[[2018,1]]}}}