{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,1]],"date-time":"2026-10-01T04:23:14Z","timestamp":1790828594446,"version":"4.1.0"},"reference-count":21,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"1","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2018,1]]},"abstract":"\n OBJECTIVE<\/jats:title>\n Postoperative decrease in ventricle size is usually not detectable either by visual assessment or by measuring the Evans index in patients with idiopathic normal pressure hydrocephalus (iNPH). The aim of the present study was to investigate whether the angle between the lateral ventricles (the callosal angle [CA]) increases and ventricular volume decreases after shunt surgery in patients with iNPH.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n Magnetic resonance imaging of the brain was performed before and 3 months after shunt surgery in 18 patients with iNPH. The CA and Evans index were measured on T1-weighted 3D MR images, and ventricular volume contralateral to the shunt valve was measured with quantitative MRI.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n The CA was larger postoperatively (mean 78\u00b0, 95% CI 69\u00b0\u201387\u00b0) than preoperatively (mean 67\u00b0, 95% CI 60\u00b0\u201373\u00b0; p < 0.001). The volume of the lateral ventricle contralateral to the shunt valve decreased from 73 ml (95% CI 66\u201380 ml) preoperatively to 63 ml (95% CI 54\u201372 ml) postoperatively (p < 0.001). The Evans index was 0.365 (95% CI 0.35\u20130.38) preoperatively and 0.358 (95% CI 0.34\u20130.38) postoperatively (p < 0.05). Postoperative change of CA showed a negative correlation with change of ventricular volume (r = \u22120.76, p < 0.01).<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n In this sample of patients with iNPH, the CA increased and ventricular volume decreased after shunt surgery. The relative difference was most pronounced for the CA, indicating that this accessible, noninvasive radiological marker should be evaluated further as an indirect method to determine shunt function in patients with iNPH.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2017.8.jns17547","type":"journal-article","created":{"date-parts":[[2018,2,2]],"date-time":"2018-02-02T10:00:09Z","timestamp":1517565609000},"page":"130-135","source":"Crossref","is-referenced-by-count":41,"title":["Increase in callosal angle and decrease in ventricular volume after shunt surgery in patients with idiopathic normal pressure hydrocephalus"],"prefix":"10.3171","volume":"130","author":[{"given":"Johan","family":"Virhammar","sequence":"first","affiliation":[{"name":"Neurology and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katarina","family":"Laurell","sequence":"additional","affiliation":[{"name":"Department of Pharmacology and Clinical Neuroscience, Unit of Neurology, Ume\u00e5 University, Ume\u00e5, Sweden"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Kristina Giuliana","family":"Cesarini","sequence":"additional","affiliation":[{"name":"Neurosurgery; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Elna-Marie","family":"Larsson","sequence":"additional","affiliation":[{"name":"Department of Surgical Sciences, Radiology, Uppsala University, Uppsala; and"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"117","DOI":"10.1056\/NEJM196507152730301","article-title":"Symptomatic occult hydrocephalus with \u201cnormal\u201d cerebrospinal-fluid pressure. 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