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The following key words were used: \u201cradiosurgery\u201d and \u201ctremor\u201d or \u201cParkinson\u2019s disease\u201d or \u201cmultiple sclerosis\u201d or \u201cessential tremor\u201d or \u201cthalamotomy\u201d or \u201cpallidotomy.\u201d The search strategy was not limited by study design but only included key words in the English language, so at least the abstract had to be in English.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>A total of 34 full-text articles were included in the analysis. Three studies were prospective studies, 1 was a retrospective comparative study, and the remaining 30 were retrospective studies. The one retrospective comparative study evaluating deep brain stimulation (DBS), radiofrequency thermocoagulation (RFT), and SRS reported similar tremor control rates, more permanent complications after DBS and RFT, more recurrence after RFT, and a longer latency period to clinical response with SRS. Similar tremor reduction rates in most of the reports were observed with SRS thalamotomy (mean 88%). Clinical complications were rare and usually not permanent (range 0%\u2013100%, mean 17%, median 2%). Follow-up in general was too short to confirm long-term results.<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>SRS to the unilateral thalamic ventral intermediate nucleus, with a dose of 130\u2013150 Gy, is a well-tolerated and effective treatment for reducing medically refractory tremor, and one that is recommended by the International Stereotactic Radiosurgery Society.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2017.8.jns17749","type":"journal-article","created":{"date-parts":[[2018,2,23]],"date-time":"2018-02-23T16:08:43Z","timestamp":1519402123000},"page":"589-600","source":"Crossref","is-referenced-by-count":40,"title":["Stereotactic radiosurgery for tremor: systematic review"],"prefix":"10.3171","volume":"130","author":[{"given":"Nuria E.","family":"Mart\u00ednez-Moreno","sequence":"first","affiliation":[{"name":"Department of Radiosurgery and Functional Neurosurgery, Ruber International Hospital, Madrid, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Arjun","family":"Sahgal","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, University of Toronto, Sunnybrook Odette Cancer Centre, Toronto, Ontario, Canada;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Antonio","family":"De Salles","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of California, Los Angeles, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Motohiro","family":"Hayashi","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Tokyo Women\u2019s Medical University, Tokyo, Japan;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Marc","family":"Levivier","sequence":"additional","affiliation":[{"name":"Neurosurgery Service and Gamma Knife Center, Centre Hospitalier Universitaire Vaudois, Lausanne, Switzerland;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lijun","family":"Ma","sequence":"additional","affiliation":[{"name":"Division of Physics, Department of Radiation Oncology, University of California, San Francisco, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ian","family":"Paddick","sequence":"additional","affiliation":[{"name":"Division of Physics, National Hospital for Neurology and Neurosurgery, London, United Kingdom;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jean","family":"R\u00e9gis","sequence":"additional","affiliation":[{"name":"Department of Functional Neurosurgery, Timone University Hospital, Aix-Marseille University, Marseille, France;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Sam","family":"Ryu","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, Stony Brook University, Stony Brook, New York; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ben J.","family":"Slotman","sequence":"additional","affiliation":[{"name":"Department of Radiation Oncology, VU University Medical Center, Amsterdam, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Roberto","family":"Mart\u00ednez-\u00c1lvarez","sequence":"additional","affiliation":[{"name":"Department of Radiosurgery and Functional Neurosurgery, Ruber International Hospital, Madrid, Spain;"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Surg Neurol","doi-asserted-by":"publisher","first-page":"559","DOI":"10.1016\/j.surneu.2006.08.002","article-title":"A review of 3 current radiosurgery systems","volume":"66","author":"Andrews DW","year":"2006","unstructured":"Andrews DW, Bednarz G, Evans JJ, Downes B: A review of 3 current radiosurgery systems. 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