{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,29]],"date-time":"2026-09-29T06:43:45Z","timestamp":1790664225104,"version":"4.1.0"},"reference-count":23,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"3","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,3]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>The clinical results of reoperation for recurrent or persistent ulnar nerve compression at the elbow have not been clearly determined. The aim of this review was to determine overall improvement, residual pain, and sensory and motor deficits following reoperation regardless of the type of primary surgery performed for this condition.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>In accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) recommendations, a systematic review and meta-analysis of studies was performed. An independent librarian performed a literature search using Ovid MEDLINE, Embase, CINAHL, and the Cochrane Central Register of Controlled Trials (CENTRAL). The Newcastle-Ottawa Scale and the quality appraisal tool described by Moga et al. were used to assess the quality of included case series.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>Of the 278 retrieved studies, 16 were eligible for analysis and included a total of 290 patients with failed surgery for ulnar nerve entrapment at the elbow. Relief of symptoms after reoperation was reported in 85% of patients. A decrease in pain was noted in 85% of the patients (95% CI 75%\u201393%). Only 2.4% of patients with preoperative pain experienced worse pain after reoperation. Motor and sensory function improvement was noted in 77% (95% CI 63%\u201388%) and 77% (95% CI 61%\u201390%) of cases, respectively. Complete recovery from signs and symptoms at the final follow-up was noted in 23% of elbows (95% CI 16%\u201331%).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Although the level of evidence of the included studies was low, the majority of patients had relief from their complaints after reoperation for recurrent or persistent ulnar nerve compression at the elbow following a previous surgery. The success rate of surgical treatment for a failed surgery was quite remarkable since almost a quarter of the patients completely recovered. Therefore, the authors recommend reoperation as a serious option for patients with this condition.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2017.8.jns17927","type":"journal-article","created":{"date-parts":[[2018,5,11]],"date-time":"2018-05-11T13:59:16Z","timestamp":1526047156000},"page":"686-701","source":"Crossref","is-referenced-by-count":8,"title":["Results of reoperation for failed ulnar nerve surgery at the elbow: a systematic review and meta-analysis"],"prefix":"10.3171","volume":"130","author":[{"given":"Tinatin","family":"Natroshvili","sequence":"first","affiliation":[{"name":"Departments of Plastic and Reconstructive Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Erik T.","family":"Walbeehm","sequence":"additional","affiliation":[{"name":"Departments of Plastic and Reconstructive Surgery;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nens","family":"van Alfen","sequence":"additional","affiliation":[{"name":"Department of Neurology, Donders Institute for Brain, Cognition and Behaviour; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ronald H. M. A.","family":"Bartels","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, Radboud University Medical Center, Nijmegen, The Netherlands"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"J Hand Surg Am","doi-asserted-by":"publisher","first-page":"2141","DOI":"10.1016\/j.jhsa.2014.07.013","article-title":"Outcomes of revision surgery for cubital tunnel syndrome","volume":"39","author":"Aleem AW","year":"2014","unstructured":"Aleem AW, Krogue JD, Calfee RP: Outcomes of revision surgery for cubital tunnel syndrome. J Hand Surg Am 39:2141\u20132149, 20142516941710.1016\/j.jhsa.2014.07.013"},{"key":"b2","series-title":"Neurosurgery","first-page":"585","article-title":"Pain after surgery for ulnar neuropathy at the elbow: a continuing challenge","volume":"41","author":"Antoniadis G","year":"1997","unstructured":"Antoniadis G, Richter HP: Pain after surgery for ulnar neuropathy at the elbow: a continuing challenge. Neurosurgery 41:585\u2013591, 19979310975"},{"key":"b3","series-title":"J Bone Joint Surg Br","doi-asserted-by":"publisher","first-page":"998","DOI":"10.1302\/0301-620X.86B7.14877","article-title":"Anterior submuscular transposition of the ulnar nerve. For post-operative focal neuropathy at the elbow","volume":"86","author":"Bartels RHMA","year":"2004","unstructured":"Bartels RHMA, Grotenhuis JA: Anterior submuscular transposition of the ulnar nerve. For post-operative focal neuropathy at the elbow. J Bone Joint Surg Br 86:998\u20131001, 200410.1302\/0301-620X.86B7.1487715446526"},{"key":"b4","series-title":"J Neurosurg","doi-asserted-by":"publisher","first-page":"722","DOI":"10.3171\/jns.1998.89.5.0722","article-title":"Surgical management of ulnar nerve compression at the elbow: an analysis of the literature","volume":"89","author":"Bartels RHMA","year":"1998","unstructured":"Bartels RHMA, Menovsky T, Van Overbeeke JJ, Verhagen WIM: Surgical management of ulnar nerve compression at the elbow: an analysis of the literature. J Neurosurg 89:722\u2013727, 199810.3171\/jns.1998.89.5.07229817408"},{"key":"b5","series-title":"J Hand Surg Am","doi-asserted-by":"publisher","first-page":"85","DOI":"10.1016\/S0363-5023(78)80121-X","article-title":"Technical problems with ulnar nerve transposition at the elbow: findings and results of reoperation","volume":"3","author":"Broudy AS","year":"1978","unstructured":"Broudy AS, Leffert RD, Smith RJ: Technical problems with ulnar nerve transposition at the elbow: findings and results of reoperation. J Hand Surg Am 3:85\u201389, 197862137110.1016\/S0363-5023(78)80121-X"},{"key":"b6","series-title":"J Hand Surg Am","doi-asserted-by":"publisher","first-page":"544","DOI":"10.1053\/jhsu.2000.6005","article-title":"Subcutaneous anterior transposition of the ulnar nerve for failed decompression of cubital tunnel syndrome","volume":"25","author":"Caputo AE","year":"2000","unstructured":"Caputo AE, Watson HK: Subcutaneous anterior transposition of the ulnar nerve for failed decompression of cubital tunnel syndrome. J Hand Surg Am 25:544\u2013551, 200010.1053\/jhsu.2000.600510811760"},{"key":"b7","series-title":"Int Orthop","first-page":"342","article-title":"Simple neurolysis for failed anterior submuscular transposition of the ulnar nerve at the elbow","volume":"28","author":"Dagregorio G","year":"2004","unstructured":"Dagregorio G, Saint-Cast Y: Simple neurolysis for failed anterior submuscular transposition of the ulnar nerve at the elbow. Int Orthop 28:342\u2013346, 200415597170"},{"key":"b8","series-title":"Minim Invasive Neurosurg","doi-asserted-by":"publisher","first-page":"197","DOI":"10.1055\/s-2001-19937","article-title":"Recurrent cubital tunnel syndrome. Etiology and treatment","volume":"44","author":"Filippi R","year":"2001","unstructured":"Filippi R, Charalampaki P, Reisch R, Koch D, Grunert P: Recurrent cubital tunnel syndrome. Etiology and treatment. Minim Invasive Neurosurg 44:197\u2013201, 200110.1055\/s-2001-1993711830777"},{"key":"b9","series-title":"J Bone Joint Surg Am","doi-asserted-by":"publisher","first-page":"213","DOI":"10.2106\/00004623-199072020-00008","article-title":"Reoperation for failed decompression of the ulnar nerve in the region of the elbow","volume":"72","author":"Gabel GT","year":"1990","unstructured":"Gabel GT, Amadio PC: Reoperation for failed decompression of the ulnar nerve in the region of the elbow. J Bone Joint Surg Am 72:213\u2013219, 1990230350710.2106\/00004623-199072020-00008"},{"key":"b10","series-title":"J Hand Surg Eur","doi-asserted-by":"publisher","first-page":"379","DOI":"10.1177\/1753193408101467","article-title":"Incidence of re-operation and subjective outcome following in situ decompression of the ulnar nerve at the cubital tunnel","volume":"34","author":"Goldfarb CA","year":"2009","unstructured":"Goldfarb CA, Sutter MM, Martens EJ, Manske PR: Incidence of re-operation and subjective outcome following in situ decompression of the ulnar nerve at the cubital tunnel. J Hand Surg Eur Vol. 34:379\u2013383, 200910.1177\/1753193408101467"},{"key":"b11","series-title":"BMJ","doi-asserted-by":"publisher","first-page":"557","DOI":"10.1136\/bmj.327.7414.557","article-title":"Measuring inconsistency in meta-analyses","volume":"327","author":"Higgins JPT","year":"2003","unstructured":"Higgins JPT, Thompson SG, Deeks JJ, Altman DG: Measuring inconsistency in meta-analyses. BMJ 327:557\u2013560, 20031295812010.1136\/bmj.327.7414.557"},{"key":"b12","series-title":"Scand J Plast Reconstr Surg Hand Surg","doi-asserted-by":"publisher","first-page":"173","DOI":"10.3109\/02844319109111279","article-title":"Reoperation in high ulnar neuropathy","volume":"25","author":"Holmberg J","year":"1991","unstructured":"Holmberg J: Reoperation in high ulnar neuropathy. Scand J Plast Reconstr Surg Hand Surg 25:173\u2013176, 199110.3109\/028443191091112791947888"},{"issue":"2 Suppl","key":"b13","series-title":"J Shoulder Elbow Surg","doi-asserted-by":"publisher","first-page":"91","DOI":"10.1016\/j.jse.2009.12.019","article-title":"Vein wrapping at cubital tunnel for ulnar nerve problems","volume":"19","author":"Kokkalis ZT","year":"2010","unstructured":"Kokkalis ZT, Jain S, Sotereanos DG: Vein wrapping at cubital tunnel for ulnar nerve problems. J Shoulder Elbow Surg 19 (2 Suppl):91\u201397, 201010.1016\/j.jse.2009.12.01920188273"},{"key":"b14","series-title":"Development of a quality appraisal tool for case series studies using a modified Delphi technique","author":"Moga C","year":"2012","unstructured":"Moga C, Guo B, Schopflocher D, Harstall C: Development of a quality appraisal tool for case series studies using a modified Delphi technique. Edmonton: Institute of Health Economics, 2012 (https:\/\/www.ihe.ca\/publications\/development-of-a-quality-appraisal-tool-for-case-series-studies-using-a-modified-delphi-technique) [Accessed January 23, 2018]"},{"key":"b15","series-title":"BMJ","doi-asserted-by":"publisher","first-page":"b2535","DOI":"10.1136\/bmj.b2535","article-title":"Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement","volume":"339","author":"Moher D","year":"2009","unstructured":"Moher D, Liberati A, Tetzlaff J, Altman DG: Preferred reporting items for systematic reviews and meta-analyses: the PRISMA statement. BMJ 339:b2535, 200910.1136\/bmj.b253519622551"},{"key":"b16","series-title":"J Neurol Sci","doi-asserted-by":"publisher","first-page":"5","DOI":"10.1016\/j.jns.2005.02.010","article-title":"Incidence of ulnar neuropathy at the elbow in the province of Siena (Italy)","volume":"234","author":"Mondelli M","year":"2005","unstructured":"Mondelli M, Giannini F, Ballerini M, Ginanneschi F, Martorelli E: Incidence of ulnar neuropathy at the elbow in the province of Siena (Italy). J Neurol Sci 234:5\u201310, 200510.1016\/j.jns.2005.02.01015993135"},{"key":"b17","series-title":"J Hand Surg Am","doi-asserted-by":"publisher","first-page":"987","DOI":"10.1016\/j.jhsa.2015.02.031","article-title":"Preliminary results of recurrent cubital tunnel syndrome treated with neurolysis and porcine extracellular matrix nerve wrap","volume":"40","author":"Papatheodorou LK","year":"2015","unstructured":"Papatheodorou LK, Williams BG, Sotereanos DG: Preliminary results of recurrent cubital tunnel syndrome treated with neurolysis and porcine extracellular matrix nerve wrap. J Hand Surg Am 40:987\u2013992, 20152591121010.1016\/j.jhsa.2015.02.031"},{"key":"b18","series-title":"Clin Orthop Relat Res (269)","first-page":"193","article-title":"The failed ulnar nerve transposition. Etiology and treatment","author":"Rogers MR","year":"1991","unstructured":"Rogers MR, Bergfield TG, Aulicino PL: The failed ulnar nerve transposition. Etiology and treatment. Clin Orthop Relat Res (269):193\u2013200, 1991"},{"key":"b19","series-title":"J Reconstr Microsurg","doi-asserted-by":"publisher","first-page":"665","DOI":"10.1055\/s-2002-36497","article-title":"Medial brachial and antebrachial cutaneous nerve injuries: effect on outcome in revision cubital tunnel surgery","volume":"18","author":"Sarris I","year":"2002","unstructured":"Sarris I, G\u00f6bel F, Gainer M, Vardakas DG, Vogt MT, Sotereanos DG: Medial brachial and antebrachial cutaneous nerve injuries: effect on outcome in revision cubital tunnel surgery. J Reconstr Microsurg 18:665\u2013670, 20021252458410.1055\/s-2002-36497"},{"key":"b20","series-title":"Ann Plast Surg","doi-asserted-by":"publisher","first-page":"572","DOI":"10.1097\/SAP.0b013e3182956475","article-title":"Revision decompression and collagen nerve wrap for recurrent and persistent compression neuropathies of the upper extremity","volume":"72","author":"Soltani AM","year":"2014","unstructured":"Soltani AM, Allan BJ, Best MJ, Mir HS, Panthaki ZJ: Revision decompression and collagen nerve wrap for recurrent and persistent compression neuropathies of the upper extremity. Ann Plast Surg 72:572\u2013578, 201410.1097\/SAP.0b013e318295647524322638"},{"key":"b21","series-title":"Br J Plast Surg","doi-asserted-by":"publisher","first-page":"311","DOI":"10.1016\/j.bjps.2004.02.027","article-title":"Revision anterior submuscular transposition of the ulnar nerve for failed subcutaneous transposition","volume":"57","author":"Vogel RB","year":"2004","unstructured":"Vogel RB, Nossaman BC, Rayan GM: Revision anterior submuscular transposition of the ulnar nerve for failed subcutaneous transposition. Br J Plast Surg 57:311\u2013316, 200410.1016\/j.bjps.2004.02.02715145733"},{"key":"b22","series-title":"Int J Surg","doi-asserted-by":"publisher","first-page":"1495","DOI":"10.1016\/j.ijsu.2014.07.013","article-title":"The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies","volume":"12","author":"von Elm E","year":"2014","unstructured":"von Elm E, Altman DG, Egger M, Pocock SJ, G\u00f8tzsche PC, Vandenbroucke JP: The Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) Statement: guidelines for reporting observational studies. Int J Surg 12:1495\u20131499, 201410.1016\/j.ijsu.2014.07.013"},{"key":"b23","series-title":"Ottawa Hospital Research Institute","article-title":"The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses","author":"Wells GA","unstructured":"Wells GA, Shea B, O\u2019Connell D, Peterson J, Welch V, Losos M, : The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research Institute. (http:\/\/www.ohri.ca\/programs\/clinical_epidemiology\/oxford.asp)[Accessed January 23, 2018]"}],"container-title":["Journal of Neurosurgery"],"original-title":[],"link":[{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/130\/3\/article-p686.xml","content-type":"text\/html","content-version":"vor","intended-application":"text-mining"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/130\/3\/article-p686.xml","content-type":"text\/html","content-version":"vor","intended-application":"syndication"},{"URL":"https:\/\/thejns.org\/downloadpdf\/journals\/j-neurosurg\/130\/3\/article-p686.xml","content-type":"unspecified","content-version":"vor","intended-application":"similarity-checking"}],"deposited":{"date-parts":[[2023,3,26]],"date-time":"2023-03-26T06:52:00Z","timestamp":1679813520000},"score":1,"resource":{"primary":{"URL":"https:\/\/thejns.org\/view\/journals\/j-neurosurg\/130\/3\/article-p686.xml"}},"subtitle":[],"short-title":[],"issued":{"date-parts":[[2019,3]]},"references-count":23,"journal-issue":{"issue":"3"},"URL":"https:\/\/doi.org\/10.3171\/2017.8.jns17927","relation":{},"ISSN":["0022-3085","1933-0693"],"issn-type":[{"value":"0022-3085","type":"print"},{"value":"1933-0693","type":"electronic"}],"subject":[],"published":{"date-parts":[[2019,3]]}}}