{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,10,20]],"date-time":"2026-10-20T02:00:33Z","timestamp":1792461633777,"version":"4.5.0"},"reference-count":53,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,5]]},"abstract":"\n OBJECTIVE<\/jats:title>\n Symptomatic perineural or Tarlov cysts (TCs) are a rare cause of chronic low-back pain. Given the rarity of the disease, there is no literature consensus regarding the optimal management of these cysts.<\/jats:p>\n <\/jats:sec>\n \n METHODS<\/jats:title>\n The authors conducted a systematic comparative outcome analysis of symptomatic TCs treated with surgery (group A, 32 studies, n = 333) or percutaneous interventions (group B, 6 studies, n = 417) analyzing the demographic characteristics, baseline characteristics of the cysts, clinical presentations, types of interventions, complication rates, and the recurrence rate in both treatment groups. The literature search was performed using the PubMed, MEDLINE, Cochrane, and Ovid databases up to 2018. The MeSH search terms used were \u201cTarlov cyst,\u201d \u201csacral perineural cyst,\u201d \u201csacral nerve root cyst,\u201d \u201cmeningeal cyst of the sacral spine,\u201d \u201cextra meningeal cyst with spinal nerve root fibers,\u201d \u201cspinal extradural arachnoid pouch,\u201d and \u201ccyst of the sacral nerve root sheath.\u201d The authors used statistical tests for two proportions using the \u201cN-1\u201d chi-square test with the free version of MedCalc for Windows for comparison among the groups.<\/jats:p>\n <\/jats:sec>\n \n RESULTS<\/jats:title>\n Overall symptomatic improvement was reported in 83.5% of patients in both groups; however, exacerbation of preprocedural symptoms was significantly higher in group B than group A (10.1% vs 3.3%, p = 0.0003). The overall complication rates in the surgical and nonsurgical groups were 21% and 12.47%, respectively. Transient sciatica was the most common complication in both groups (17% vs 8%, respectively; p = 0.017). The incidence of cyst recurrence was much lower in group A than group B (8% vs 20%, p = 0.0018). The mean follow-up duration for the surgical group was 38 \u00b1 29 months (25 studies, n = 279), while that for the nonsurgical group was 15 \u00b1 12 months (4 studies, n = 290) (p < 0.0001).<\/jats:p>\n <\/jats:sec>\n \n CONCLUSIONS<\/jats:title>\n The authors noted that although the surgical interventions were associated with higher postprocedural complication rates, long-term efficacy and success in terms of cyst resolution were superior following surgery compared to percutaneous procedures in the management of symptomatic TCs. There was no difference in symptom recurrence with either of the techniques.<\/jats:p>\n <\/jats:sec>","DOI":"10.3171\/2018.10.spine18952","type":"journal-article","created":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T20:12:26Z","timestamp":1551211946000},"page":"623-634","source":"Crossref","is-referenced-by-count":37,"title":["A systematic comparative outcome analysis of surgical versus percutaneous techniques in the management of symptomatic sacral perineural (Tarlov) cysts: a meta-analysis"],"prefix":"10.3171","volume":"30","author":[{"given":"Mayur","family":"Sharma","sequence":"first","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Pooja","family":"SirDeshpande","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Beatrice","family":"Ugiliweneza","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Nicholas","family":"Dietz","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Maxwell","family":"Boakye","sequence":"additional","affiliation":[],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"Clin Orthop","first-page":"149","article-title":"Perineurial cysts; review of literature and report of eight cases","volume":"7","author":"Abbott KH","year":"1956","unstructured":"Abbott KH: Perineurial cysts; review of literature and report of eight cases. 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