{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,5,30]],"date-time":"2026-05-30T09:05:20Z","timestamp":1780131920395,"version":"3.54.0"},"reference-count":58,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"2","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2019,2]]},"abstract":"<jats:sec>\n                    <jats:title>OBJECTIVE<\/jats:title>\n                    <jats:p>Sylvian fissure dissection following subarachnoid hemorrhage (SAH) is a challenging but fundamental skill in microneurosurgery, and one that has become increasingly difficult to develop during residency, given the overarching management trends. The authors describe a novel rodent model for simulation of sylvian fissure dissection and cerebrovascular bypass under SAH conditions.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>METHODS<\/jats:title>\n                    <jats:p>A standardized microvascular anastomosis model comprising rat femoral arteries and veins was used for the experimental framework. In the experimental protocol, following exposure and skeletonization of the vessels, extensive, superficial (1- to 2-mm) soft-tissue debridement was conducted and followed by wound closure and delayed reexploration at intervals of 7, 14, and 28 days. Two residents dissected 1 rat each per time point (n = 6 rats), completing vessel skeletonization followed by end-to-end artery\/vein anastomoses. Videos were reviewed postprocedure to assess scar score and relative difficulty of dissection by blinded raters using 4-point Likert scales.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>RESULTS<\/jats:title>\n                    <jats:p>At all time points, vessels were markedly invested in friable scar, and exposure was subjectively assessed as a reasonable surrogate for sylvian fissure dissection under SAH conditions. Scar score and relative difficulty of dissection both indicated 14 days as the most challenging time point.<\/jats:p>\n                  <\/jats:sec>\n                  <jats:sec>\n                    <jats:title>CONCLUSIONS<\/jats:title>\n                    <jats:p>The authors\u2019 experimental model of femoral vessel skeletonization, circumferential superficial soft-tissue injury, and delayed reexploration provides a novel approximation of sylvian fissure dissection and cerebrovascular bypass under SAH conditions. The optimal reexploration interval appears to be 7\u201314 days. To the authors\u2019 knowledge, this is the first model of SAH simulation for microsurgical training, particularly in a live animal system.<\/jats:p>\n                  <\/jats:sec>","DOI":"10.3171\/2018.11.focus18533","type":"journal-article","created":{"date-parts":[[2019,2,26]],"date-time":"2019-02-26T20:59:11Z","timestamp":1551214751000},"page":"E17","source":"Crossref","is-referenced-by-count":8,"title":["Novel rodent model for simulation of sylvian fissure dissection and cerebrovascular bypass under subarachnoid hemorrhage conditions: technical note and timing study"],"prefix":"10.3171","volume":"46","author":[{"given":"Avital","family":"Perry","sequence":"first","affiliation":[{"name":"Departments of Neurologic Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Christopher S.","family":"Graffeo","sequence":"additional","affiliation":[{"name":"Departments of Neurologic Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lucas P.","family":"Carlstrom","sequence":"additional","affiliation":[{"name":"Departments of Neurologic Surgery,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"William J.","family":"Anding","sequence":"additional","affiliation":[{"name":"Education,"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Michael J.","family":"Link","sequence":"additional","affiliation":[{"name":"Departments of Neurologic Surgery,"},{"name":"Otolaryngology\u2013Head and Neck Surgery, and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Leonardo","family":"Rangel-Castilla","sequence":"additional","affiliation":[{"name":"Departments of Neurologic Surgery,"},{"name":"Radiology, Mayo Clinic, Rochester, Minnesota"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"World Neurosurg","doi-asserted-by":"publisher","first-page":"35","DOI":"10.1016\/j.wneu.2014.01.015","article-title":"Three-dimensional hollow intracranial aneurysm models and their potential role for teaching, simulation, and training","volume":"83","author":"Abla AA","year":"2015","unstructured":"Abla AA, Lawton MT: Three-dimensional hollow intracranial aneurysm models and their potential role for teaching, simulation, and training. 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