{"status":"ok","message-type":"work","message-version":"1.0.0","message":{"indexed":{"date-parts":[[2026,9,18]],"date-time":"2026-09-18T11:03:19Z","timestamp":1789729399720,"version":"4.0.1"},"reference-count":45,"publisher":"Journal of Neurosurgery Publishing Group (JNSPG)","issue":"5","content-domain":{"domain":[],"crossmark-restriction":false},"short-container-title":[],"published-print":{"date-parts":[[2020,5]]},"abstract":"<jats:sec><jats:title>OBJECTIVE<\/jats:title><jats:p>Deep vein thrombosis (DVT) is a major focus of patient safety indicators and a common cause of morbidity and mortality. Many practices have employed lower-extremity screening ultrasonography in addition to chemoprophylaxis and the use of sequential compression devices in an effort to reduce poor outcomes. However, the role of screening in directly decreasing pulmonary emboli (PEs) and mortality is unclear. At the University of Mississippi Medical Center, a policy change provided the opportunity to compare independent groups: patients treated under a prior paradigm of weekly screening ultrasonography versus a post\u2013policy change group in which weekly surveillance was no longer performed.<\/jats:p><\/jats:sec><jats:sec><jats:title>METHODS<\/jats:title><jats:p>A total of 2532 consecutive cases were reviewed, with a 4-month washout period around the time of the policy change. Criteria for inclusion were admission to the neurosurgical service or consultation for \u2265 72 hours and hospitalization for \u2265 72 hours. Patients with a known diagnosis of DVT on admission or previous inferior vena cava (IVC) filter placement were excluded. The primary outcome examined was the rate of PE diagnosis, with secondary outcomes of all-cause mortality at discharge, DVT diagnosis rate, and IVC filter placement rate. A p value &lt; 0.05 was considered significant.<\/jats:p><\/jats:sec><jats:sec><jats:title>RESULTS<\/jats:title><jats:p>A total of 485 patients met the criteria for the pre\u2013policy change group and 504 for the post\u2013policy change group. Data are presented as screening (pre\u2013policy change) versus no screening (post\u2013policy change). There was no difference in the PE rate (2% in both groups, p = 0.72) or all-cause mortality at discharge (7% vs 6%, p = 0.49). There were significant differences in the lower-extremity DVT rate (10% vs 3%, p &lt; 0.01) or IVC filter rate (6% vs 2%, p &lt; 0.01).<\/jats:p><\/jats:sec><jats:sec><jats:title>CONCLUSIONS<\/jats:title><jats:p>Based on these data, screening Doppler ultrasound examinations, in conjunction with standard-of-practice techniques to prevent thromboembolism, do not appear to confer a benefit to patients. While the screening group had significantly higher rates of DVT diagnosis and IVC filter placement, the screening, additional diagnoses, and subsequent interventions did not appear to improve patient outcomes. Ultimately, this makes DVT screening difficult to justify.<\/jats:p><\/jats:sec>","DOI":"10.3171\/2018.12.jns182800","type":"journal-article","created":{"date-parts":[[2019,4,27]],"date-time":"2019-04-27T07:20:04Z","timestamp":1556349604000},"page":"1589-1597","source":"Crossref","is-referenced-by-count":6,"title":["Screening duplex ultrasonography in neurosurgery patients does not correlate with a reduction in pulmonary embolism rate or decreased mortality"],"prefix":"10.3171","volume":"132","author":[{"given":"James C.","family":"Dickerson","sequence":"first","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"},{"name":"Department of Medicine, Stanford University, Stanford, California;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Katherine L.","family":"Harriel","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Robert J.","family":"Dambrino","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"},{"name":"Department of Neurological Surgery, Vanderbilt University, Nashville, Tennessee;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Lorne I.","family":"Taylor","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"},{"name":"Department of Medicine, University of Tennessee Health Science Center, Memphis, Tennessee; and"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jordan A.","family":"Rimes","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Ryan W.","family":"Chapman","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Andrew S.","family":"Desrosiers","sequence":"additional","affiliation":[{"name":"University of Mississippi School of Medicine, Jackson, Mississippi;"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Jason E.","family":"Tullis","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi"}],"role":[{"vocabulary":"crossref","role":"author"}]},{"given":"Chad W.","family":"Washington","sequence":"additional","affiliation":[{"name":"Department of Neurosurgery, University of Mississippi Medical Center, Jackson, Mississippi"}],"role":[{"vocabulary":"crossref","role":"author"}]}],"member":"1754","reference":[{"key":"b1","series-title":"N Engl J Med","doi-asserted-by":"publisher","first-page":"80","DOI":"10.1056\/NEJM199807093390204","article-title":"Enoxaparin plus compression stockings compared with compression stockings alone in the prevention of venous thromboembolism after elective neurosurgery","volume":"339","author":"Agnelli G","year":"1998","unstructured":"Agnelli G, Piovella F, Buoncristiani P, Severi P, Pini M, D\u2019Angelo A, : Enoxaparin plus compression stockings compared with compression stockings alone in the prevention of venous thromboembolism after elective neurosurgery. 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